Search Results - "Mir, K. U."
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Complete sequence-based pathway analysis by differential on-chip DNA and RNA extraction from a single cell
Published in Scientific reports (08-09-2017)“…We demonstrate on-chip, differential DNA and RNA extraction from a single cell using a microfluidic chip and a two-stage lysis protocol. This method enables…”
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Determining the influence of structure on hybridization using oligonucleotide arrays
Published in Nature biotechnology (01-08-1999)“…We have studied the effects of structure on nucleic acid heteroduplex formation by analyzing hybridization of tRNAphe to a complete set of complementary…”
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Selecting effective antisense reagents on combinatorial oligonucleotide arrays
Published in Nature biotechnology (01-06-1997)“…An array of 1,938 oligodeoxynucleotides (ONs) ranging in length from monomers to 17-mers was fabricated on the surface of a glass plate and used to measure the…”
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Arrays of complementary oligonucleotides for analysing the hybridisation behaviour of nucleic acids
Published in Nucleic acids research (25-04-1994)“…Arrays of oligonucleotides corresponding to a full set of complements of a known sequence can be made in a single series of base couplings in which each base…”
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Oligonucleotide dendrimers: stable nano-structures
Published in Nucleic acids research (01-08-1999)“…DNA dendrimers with two, three, six, nine or 27 arms were reassociated as complementary pairs in solution or with an array of complementary oligonucleotides on…”
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Visualizing the entire DNA from a chromosome in a single frame
Published in Biomicrofluidics (01-07-2015)“…The contiguity and phase of sequence information are intrinsic to obtain complete understanding of the genome and its relationship to phenotype. We report the…”
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Studies of oligonucleotide interactions by hybridisation to arrays: the influence of dangling ends on duplex yield
Published in Nucleic acids research (25-04-1994)“…Effects of dangling ends on duplex yield have been assessed by hybridisation of oligonucleotldes to an array of oligonucleotldes syntheslsed on the surface of…”
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The hypothesis is there is no hypothesis: The Microarray Meeting, Scottsdale, Arizona, USA, 22–25 September 1999
Published in Trends in genetics (01-02-2000)Get full text
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SEQUENCE VARIATION IN GENES AND GENOMIC DNA: Methods for Large-Scale Analysis
Published in Annual review of genomics and human genetics (01-01-2000)“…The large-scale typing of sequence variation in genes and genomic DNA presents new challenges for which it is not clear that current technologies are…”
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Lipid-Based Passivation in Nanofluidics
Published in Nano letters (09-05-2012)“…Stretching DNA in nanochannels is a useful tool for direct, visual studies of genomic DNA at the single molecule level. To facilitate the study of the…”
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Biochips: from chipped gels to microfluidic CDs
Published in Drug discovery today (01-11-1998)Get full text
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Analysing genetic information with DNA arrays
Published in Current opinion in chemical biology (01-06-1998)“…The large amount of DNA sequence information produced in recent years has created a need for high-throughput methods in biology and genetics. These include…”
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Discovering antisense reagents by hybridization of RNA to oligonucleotide arrays
Published in Ciba Foundation symposium (1997)“…Antisense reagents have the potential to modify gene expression by interacting with DNA or mRNA to down-regulate transcription or translation. There have been…”
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Erratum: Determining the influence of structure on hybridization using oligonucleotide arrays
Published in Nature biotechnology (01-10-1999)Get full text
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Sequencing Genomes: From Individuals to Populations
Published in Briefings in functional genomics & proteomics (01-09-2009)“…The whole genome sequences of Jim Watson and Craig Venter are early examples of personalized genomics, which promises to change how we approach healthcare in…”
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