Search Results - "Miquet, Johanna G"

Growth hormone modulation of insulin signaling in the heart by Miquet, Johanna G.

“…Comment on: Miquet JG, et al. J Mol Endocrinol 2011; 47:167-77…”
Get full text

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone by Miquet, Johanna G., Freund, Thomas, Martinez, Carolina S., González, Lorena, Díaz, María E., Micucci, Giannina P., Zotta, Elsa, Boparai, Ravneet K., Bartke, Andrzej, Turyn, Daniel, Sotelo, Ana I.

“…Growth hormone (GH) overexpression throughout life in transgenic mice is associated with the development of liver tumors at old ages. The preneoplastic…”
Get full text

Growth hormone upregulates the pro-tumorigenic galectin 1 in mouse liver by Bacigalupo, María L, Piazza, Verónica G, Cicconi, Nadia S, Carabias, Pablo, Bartke, Andrzej, Fang, Yimin, Sotelo, Ana I, Rabinovich, Gabriel A, Troncoso, María F, Miquet, Johanna G

“…Transgenic mice overexpressing growth hormone (GH) spontaneously develop liver tumors, including hepatocellular carcinoma (HCC), within a year. The…”
Get full text

GH modulates hepatic epidermal growth factor signaling in the mouse by González, Lorena, Díaz, Ma. Eugenia, Miquet, Johanna G, Sotelo, Ana I, Fernández, Diego, Dominici, Fernando P, Bartke, Andrzej, Turyn, Daniel

“…Epidermal growth factor (EGF) is a key regulator of cell survival and proliferation involved in the pathogenesis and progression of different types of cancer…”
Get full text

Growth hormone STAT5-mediated signaling and its modulation in mice liver during the growth period by Martinez, Carolina S, Piazza, Verónica G, Ratner, Laura D, Matos, Marina N, González, Lorena, Rulli, Susana B, Miquet, Johanna G, Sotelo, Ana I

“…Abstract Postnatal growth exhibits two instances of rapid growth in mice: the first is perinatal and independent of growth hormone (GH), the second is…”
Get full text

Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation by Miquet, Johanna G, González, Lorena, Matos, Marina N, Hansen, Christina E, Louis, Audreen, Bartke, Andrzej, Turyn, Daniel, Sotelo, Ana I

“…Chronically elevated levels of GH in GH-transgenic mice result in accelerated growth and increased adult body weight. We have previously described that the…”
Get full text

Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice by Giani, Jorge F, Miquet, Johanna G, Muñoz, Marina C, Burghi, Valeria, Toblli, Jorge E, Masternak, Michal M, Kopchick, John J, Bartke, Andrzej, Turyn, Daniel, Dominici, Fernando P

“…Abstract Objective Growth hormone (GH) resistance leads to enhanced insulin sensitivity, decreased systolic blood pressure and increased lifespan. The aim of…”
Get full text

Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice by Bartke, Andrzej, Masternak, Michal M., Miquet, Johanna G., Arum, Oge, Boparai, Ravneet K., Khardori, Romesh K.

“…Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response,…”
Get full text

Growth Hormone Modulation of Hepatic Epidermal Growth Factor Receptor Signaling by González, Lorena, Díaz, María E., Miquet, Johanna G., Sotelo, Ana I., Dominici, Fernando P.

“…Epidermal growth factor receptor (EGFR) signaling has a central role in the regenerative response of the liver upon injury and is involved in cellular…”
Get full text

Liver impact of growth hormone (GH) intermittent treatment during the growth period in mice by Piazza, Verónica G., Cicconi, Nadia S., Martinez, Carolina S., Dominici, Fernando P., Miquet, Johanna G., Sotelo, Ana I.

“…Liver impact of prolonged GH-treatment given to non-GH-deficient growing mice between the third and eighth week of life was evaluated in both sexes. Tissues…”
Get full text

Long‐lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high‐fat diet on metabolic function and energy expenditure by Hill, Cristal M., Fang, Yimin, Miquet, Johanna G., Sun, Liou Y., Masternak, Michal M., Bartke, Andrzej

“…Summary Growth hormone (GH) signaling stimulates the production of IGF‐1; however, increased GH signaling may induce insulin resistance and can reduce life…”
Get full text

Morphological and molecular effects of overexpressed GH on mice mammary gland by Bojorge, Mariana A., Cicconi, Nadia S., Cebrón, Julieta R., Fang, Yimin, Lamb, Caroline A., Bartke, Andrzej, Miquet, Johanna G., González, Lorena

“…Growth Hormone (GH) plays crucial roles in mammary gland development and growth, and its upregulation has been associated with breast cancer promotion and/or…”
Get full text

Mice lacking angiotensin type 2 receptor exhibit a sex-specific attenuation of insulin sensitivity by Quiroga, Diego T., Miquet, Johanna G., Gonzalez, Lorena, Sotelo, Ana I., Muñoz, Marina C., Geraldes, Pedro M., Giani, Jorge F., Dominici, Fernando P.

“…The renin-angiotensin system modulates insulin action. Pharmacological stimulation of angiotensin type 2 receptor (AT2R) was shown to have beneficial metabolic…”
Get full text

Oral administration of angiotensin-(1–7) ameliorates type 2 diabetes in rats by Santos, Sérgio H. S., Giani, Jorge F., Burghi, Valeria, Miquet, Johanna G., Qadri, Fatimunnisa, Braga, Janaina F., Todiras, Mihail, Kotnik, Katarina, Alenina, Natalia, Dominici, Fernando P., Santos, Robson A. S., Bader, Michael

“…Diabetes mellitus type 2 (DM2) is a disease with increasing importance in modern societies and insufficient treatment options. Pharmacological stimulation of…”
Get full text

Analysis of Different Approaches for the Selection of Reference Genes in RT-qPCR Experiments: A Case Study in Skeletal Muscle of Growing Mice by Piazza, Verónica G, Bartke, Andrzej, Miquet, Johanna G, Sotelo, Ana I

“…The reliability of reverse transcription-quantitative PCR (RT-qPCR) results in gene expression studies depends on the approaches used to account for…”
Get full text

Insulin signaling in the heart is impaired by growth hormone: a direct and early event by Muñoz, Marina C, Piazza, Verónica G, Burghi, Valeria, Giani, Jorge F, Martinez, Carolina S, Cicconi, Nadia S, Muia, Nadia V, Fang, Yimin, Lavandero, Sergio, Sotelo, Ana I, Bartke, Andrzej, Pennisi, Patricia A, Dominici, Fernando P, Miquet, Johanna G

“…Growth hormone (GH) exerts major actions in cardiac growth and metabolism. Considering the important role of insulin in the heart and the well-established…”
Get full text

Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX by Piazza, Verónica G., Matzkin, María E., Cicconi, Nadia S., Muia, Nadia V., Valquinta, Sofía, Mccallum, Gregorio J., Micucci, Giannina P., Freund, Thomas, Zotta, Elsa, González, Lorena, Frungieri, Mónica B., Fang, Yimin, Bartke, Andrzej, Sotelo, Ana I., Miquet, Johanna G.

“…Continuously elevated levels of growth hormone (GH) during life in mice are associated with hepatomegaly due to hepatocytes hypertrophy and hyperplasia,…”
Get full text

Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period by Martinez, Carolina S, Piazza, Verónica G, González, Lorena, Fang, Yimin, Bartke, Andrzej, Turyn, Daniel, Miquet, Johanna G, Sotelo, Ana I

“…Growth hormone (GH) is a pleiotropic hormone that triggers STATs, ERK1/2 and Akt signaling, related to cell growth and proliferation. Transgenic mice…”
Get full text

A laboratory work to introduce biochemistry undergraduate students to basic enzyme kinetics‐alkaline phosphatase as a model by Miquet, Johanna G., González, Lorena, Sotelo, Ana I., González Lebrero, Rodolfo M.

“…Enzyme kinetics is an essential topic in undergraduate Biochemistry courses. A laboratory work that covers the principal basic concepts of enzyme kinetics in…”
Get full text

Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver by Díaz, Ma. Eugenia, González, Lorena, Miquet, Johanna G., Martínez, Carolina S., Sotelo, Ana I., Bartke, Andrzej, Turyn, Daniel

“…The epidermal growth factor (EGF) activates the phosphatidylinositol 3-kinase (PI3K)-Akt cascade among other signaling pathways. This route is involved in cell…”
Get full text