Search Results - "Mioulane, Maxime"
-
1
Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?
Published in Journal of molecular and cellular cardiology (01-02-2011)“…Abstract Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are being developed for tissue repair and as a model system for cardiac physiology and…”
Get full text
Journal Article -
2
Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes
Published in PloS one (20-05-2015)“…Huntington disease (HD; OMIM 143100), a progressive neurodegenerative disorder, is caused by an expanded trinucleotide CAG (polyQ) motif in the HTT gene…”
Get full text
Journal Article -
3
Transcriptional co‐activators YAP1–TAZ of Hippo signalling in doxorubicin‐induced cardiomyopathy
Published in ESC Heart Failure (01-02-2022)“…Aims Hippo signalling is an evolutionarily conserved pathway that controls organ size by regulating apoptosis, cell proliferation, and stem cell self‐renewal…”
Get full text
Journal Article -
4
Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts
Published in Cardiovascular research (01-01-2015)“…During cardiac hypertrophy, cardiomyocytes (CMs) increase in the size and expression of cytoskeletal proteins while reactivating a foetal gene programme. The…”
Get full text
Journal Article -
5
Aberrant α-Adrenergic Hypertrophic Response in Cardiomyocytes from Human Induced Pluripotent Cells
Published in Stem cell reports (11-11-2014)“…Cardiomyocytes from human embryonic stem cells (hESC-CMs) and induced pluripotent stem cells (hiPSC-CMs) represent new models for drug discovery. Although…”
Get full text
Journal Article -
6
Development of High Content Imaging Methods for Cell Death Detection in Human Pluripotent Stem Cell-Derived Cardiomyocytes
Published in Journal of cardiovascular translational research (01-10-2012)“…Human pluripotent stem cell-derived cardiomyocytes (hPSC-CM) are being investigated as a new source of cardiac cells for drug safety assessment. We developed a…”
Get full text
Journal Article -
7
Generation and Analysis of Pluripotent Stem Cell-Derived Cardiomyocytes and Endothelial Cells for High Content Screening Purposes
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Human-induced pluripotent stem cells (hiPSCs) and their differentiated derivatives became a new, promising source for in vitro screening techniques. Cell lines…”
Get more information
Journal Article -
8
High-Content Screening, a Reliable System for Coxiella burnetii Isolation from Clinical Samples
Published in Journal of clinical microbiology (23-04-2020)“…Q fever, caused by , is a worldwide zoonotic disease that may cause severe forms in humans and requires a specific and prolonged antibiotic treatment. Although…”
Get full text
Journal Article -
9
Abstract 227: Cardiomyocytes from Human Pluripotent Stem Cells Predict Chemotherapy-Induced Cardiotoxicity
Published in Circulation research (03-08-2012)“…Abstract only The potential of human pluripotent stem cells-derived cardiomyocytes (hPSC-CM) to mimic human cardiac toxicity tests is largely unknown. Here we…”
Get full text
Journal Article -
10
Signaling via PI3K/FOXO1A pathway modulates formation and survival of human embryonic stem cell-derived endothelial cells
Published in Stem cells and development (01-04-2015)“…Vascular derivatives of human embryonic stem cells (hESC) are being developed as sources of tissue-specific cells for organ regeneration. However, identity of…”
Get more information
Journal Article -
11
Abstract P217: Nuclear Protein Import as the Missing Link in Phenylephrine-Induced Cardiomyocyte Hypertrophy
Published in Circulation research (09-12-2011)“…Abstract only During cardiac hypertrophy, cardiomyocytes (CM) present alterations in gene expression and increased contractile protein content. Nuclear protein…”
Get full text
Journal Article -
12
Immunosuppressive agents modulate function, growth, and survival of cardiomyocytes and endothelial cells derived from human embryonic stem cells
Published in Stem cells and development (01-03-2014)“…Cardiac cell replacement therapy by using human embryonic stem cell (hESC) derivatives remains a potential approach to regenerate myocardium. The major hurdles…”
Get more information
Journal Article -
13
Embryonic stem cell‐derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease
Published in Journal of cellular and molecular medicine (01-09-2009)“…Embryonic stem cell‐derived cardiomyocytes (ESC‐CM) have many of the phenotypic properties of authentic cardiomyocytes, and great interest has been shown in…”
Get full text
Journal Article -
14
Human embryonic stem cell-derived cardiomyocytes as a novel in vitro cardiac model system
Published 01-01-2011“…Objectives: Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are investigated as a source of cardiac cells for cell therapy and as a novel model for…”
Get full text
Dissertation -
15
Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes: e0126860
Published in PloS one (01-05-2015)“…Huntington disease (HD; OMIM 143100), a progressive neurodegenerative disorder, is caused by an expanded trinucleotide CAG (polyQ) motif in the HTT gene…”
Get full text
Journal Article -
16
High-content imaging and analysis of pluripotent stem cell-derived cardiomyocytes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2013)“…Human pluripotent stem cells (hPSC) are investigated as a source of authentic human cardiac cells for drug discovery and toxicological tests. Cell-based assays…”
Get more information
Journal Article