Search Results - "Minzheng Wang"

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo by Lohr, Kelly M., Bernstein, Alison I., Stout, Kristen A., Dunn, Amy R., Lazo, Carlos R., Alter, Shawn P., Wang, Minzheng, Li, Yingjie, Fan, Xueliang, Hess, Ellen J., Yi, Hong, Vecchio, Laura M., Goldstein, David S., Guillot, Thomas S., Salahpour, Ali, Miller, Gary W.

“…Disruption of neurotransmitter vesicle dynamics (transport, capacity, release) has been implicated in a variety of neurodegenerative and neuropsychiatric…”
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Increased Vesicular Monoamine Transporter 2 (VMAT2; Slc18a2) Protects against Methamphetamine Toxicity by Lohr, Kelly M, Stout, Kristen A, Dunn, Amy R, Wang, Minzheng, Salahpour, Ali, Guillot, Thomas S, Miller, Gary W

“…The psychostimulant methamphetamine (METH) is highly addictive and neurotoxic to dopamine terminals. METH toxicity has been suggested to be due to the release…”
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Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease by Richardson, Jason R, Caudle, W. Michael, Wang, Minzheng, Dean, E. Danielle, Pennell, Kurt D, Miller, Gary W

“…Exposure to pesticides has been suggested to increase the risk of Parkinson's disease (PD), but the mechanisms responsible for this association are not clear…”
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Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo by Kelly M. Lohr, Alison I. Bernstein, Kristen A. Stout, Amy R. Dunn, Carlos R. Lazo, Shawn P. Alter, Minzheng Wang, Yingjie Li, Xueliang Fan, Ellen J. Hess, Hong Yi, Laura M. Vecchio, David S. Goldstein, Thomas S. Guillot, Ali Salahpour, Gary W. Miller

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Polychlorinated Biphenyl–Induced Reduction of Dopamine Transporter Expression as a Precursor to Parkinson's Disease–Associated Dopamine Toxicity by Caudle, W. Michael, Richardson, Jason R., Delea, Kristin C., Guillot, Thomas S., Wang, Minzheng, Pennell, Kurt D., Miller, Gary W.

“…Epidemiological and laboratory studies have suggested that exposure to polychlorinated biphenyls (PCBs) may be a risk factor for Parkinson's disease. The…”
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Corrigendum to: Polychlorinated Biphenyl-Induced Reduction of Dopamine Transporter Expression as a Precursor to Parkinson's Disease-Associated Dopamine Toxicity by Caudle, W Michael, Richardson, Jason R, Delea, Kristin C, Guillot, Thomas S, Wang, Minzheng, Pennell, Kurt D, Miller, Gary W

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Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease by Dunn, Amy R., Stout, Kristen A., Ozawa, Minagi, Lohr, Kelly M., Hoffman, Carlie A., Bernstein, Alison I., Li, Yingjie, Wang, Minzheng, Sgobio, Carmelo, Sastry, Namratha, Cai, Huaibin, Caudle, W. Michael, Miller, Gary W.

“…Members of the synaptic vesicle glycoprotein 2 (SV2) family of proteins are involved in synaptic function throughout the brain. The ubiquitously expressed SV2A…”
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Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus by Taylor, Tonya N., Alter, Shawn P., Wang, Minzheng, Goldstein, David S., Miller, Gary W.

“…Parkinson's disease (PD) is the most common neurodegenerative motor disease. Pathologically, PD is characterized by Lewy body deposition and subsequent death…”
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Quantifying hail size distributions from the sky – application of drone aerial photogrammetry by Soderholm, Joshua S, Kumjian, Matthew R, McCarthy, Nicholas, Maldonado, Paula, Wang, Minzheng

“…A new technique, named “HailPixel”, is introduced for measuring the maximum dimension and intermediate dimension of hailstones from aerial imagery. The…”
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Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals by Lohr, Kelly M, Chen, Merry, Hoffman, Carlie A, McDaniel, Miranda J, Stout, Kristen A, Dunn, Amy R, Wang, Minzheng, Bernstein, Alison I, Miller, Gary W

“…The vesicular monoamine transporter 2 (VMAT2) packages neurotransmitters for release during neurotransmission and sequesters toxicants into vesicles to prevent…”
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Reduced vesicular monoamine transport disrupts serotonin signaling but does not cause serotonergic degeneration by Alter, Shawn P., Stout, Kristen A., Lohr, Kelly M., Taylor, Tonya N., Shepherd, Kennie R., Wang, Minzheng, Guillot, Thomas S., Miller, Gary W.

“…We previously demonstrated that mice with reduced expression of the vesicular monoamine transporter 2 (VMAT2 LO) undergo age-related degeneration of the…”
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Boosting Domain-Specific Question Answering Through Weakly Supervised Self-Training by Wang, Minzheng, Cao, Jia, Kong, Qingchao, Luo, Yin

“…Question answering systems have emerged as an important research area in the field of natural language processing, enabling the provision of accurate answers…”
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The Imperative of Conversation Analysis in the Era of LLMs: A Survey of Tasks, Techniques, and Trends by Zhang, Xinghua, Yu, Haiyang, Li, Yongbin, Wang, Minzheng, Chen, Longze, Huang, Fei

“…In the era of large language models (LLMs), a vast amount of conversation logs will be accumulated thanks to the rapid development trend of language UI…”
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Perinatal Heptachlor Exposure Increases Expression of Presynaptic Dopaminergic Markers in Mouse Striatum by Caudle, W. Michael, Richardson, Jason R., Wang, Minzheng, Miller, Gary W.

“…Although banned in the 1970s, significant levels of the organochlorine pesticide heptachlor are still present in the environment raising concern over potential…”
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Hierarchical Context Pruning: Optimizing Real-World Code Completion with Repository-Level Pretrained Code LLMs by Zhang, Lei, Li, Yunshui, Li, Jiaming, Xia, Xiaobo, Yang, Jiaxi, Luo, Run, Wang, Minzheng, Chen, Longze, Liu, Junhao, Yang, Min

“…Some recently developed code large language models (Code LLMs) have been pre-trained on repository-level code data (Repo-Code LLMs), enabling these models to…”
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YAYI-UIE: A Chat-Enhanced Instruction Tuning Framework for Universal Information Extraction by Xiao, Xinglin, Wang, Yijie, Xu, Nan, Wang, Yuqi, Yang, Hanxuan, Wang, Minzheng, Luo, Yin, Wang, Lei, Mao, Wenji, Zeng, Daniel

“…The difficulty of the information extraction task lies in dealing with the task-specific label schemas and heterogeneous data structures. Recent work has…”
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Leave No Document Behind: Benchmarking Long-Context LLMs with Extended Multi-Doc QA by Wang, Minzheng, Chen, Longze, Fu, Cheng, Liao, Shengyi, Zhang, Xinghua, Wu, Bingli, Yu, Haiyang, Xu, Nan, Zhang, Lei, Luo, Run, Li, Yunshui, Yang, Min, Huang, Fei, Li, Yongbin

“…Long-context modeling capabilities have garnered widespread attention, leading to the emergence of Large Language Models (LLMs) with ultra-context windows…”
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MMEvol: Empowering Multimodal Large Language Models with Evol-Instruct by Luo, Run, Zhang, Haonan, Chen, Longze, Lin, Ting-En, Liu, Xiong, Wu, Yuchuan, Yang, Min, Wang, Minzheng, Zeng, Pengpeng, Gao, Lianli, Shen, Heng Tao, Li, Yunshui, Xia, Xiaobo, Huang, Fei, Song, Jingkuan, Li, Yongbin

“…The development of Multimodal Large Language Models (MLLMs) has seen significant advancements with increasing demands in various fields (e.g., multimodal…”
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YAYI 2: Multilingual Open-Source Large Language Models by Luo, Yin, Kong, Qingchao, Xu, Nan, Cao, Jia, Hao, Bao, Qu, Baoyu, Chen, Bo, Zhu, Chao, Zhao, Chenyang, Zhang, Donglei, Feng, Fan, Zhao, Feifei, Sun, Hailong, Yang, Hanxuan, Pan, Haojun, Liu, Hongyu, Guo, Jianbin, Du, Jiangtao, Wang, Jingyi, Li, Junfeng, Sun, Lei, Liu, Liduo, Dong, Lifeng, Liu, Lili, Wang, Lin, Zhang, Liwen, Wang, Minzheng, Wang, Pin, Yu, Ping, Li, Qingxiao, Yan, Rui, Zou, Rui, Li, Ruiqun, Huang, Taiwen, Wang, Xiaodong, Wu, Xiaofei, Peng, Xin, Zhang, Xina, Fang, Xing, Xiao, Xinglin, Hao, Yanni, Dong, Yao, Wang, Yigang, Liu, Ying, Jiang, Yongyu, Wang, Yungan, Wang, Yuqi, Wang, Zhangsheng, Yu, Zhaoxin, Luo, Zhen, Mao, Wenji, Wang, Lei, Zeng, Dajun

“…As the latest advancements in natural language processing, large language models (LLMs) have achieved human-level language understanding and generation…”
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