Search Results - "Minville, Joannie"

A general synthesis of quinolinones and benzothiazine 1,1-dioxides via ring closing metathesis by Minville, Joannie, Poulin, Jason, Dufresne, Claude, Sturino, Claudio F.

“…A general synthesis of quinolinones and benzothiazine 1,1-dioxides is presented. A series of N-phenylacrylamides and N-phenylethylenesulfonamides were studied…”
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Multi-gram synthesis of a nucleotide-competing reverse transcriptase inhibitor by Duplessis, Martin, Morency, Louis, James, Clint, Minville, Joannie, Deroy, Patrick, Morin, Sébastien, Thavonekham, Bounkham, Tremblay, Martin, Halmos, Ted, Simoneau, Bruno, Bousquet, Yves, Sturino, Claudio

“…An efficient multi-gram synthesis of a nucleotide-competing reverse transcriptase inhibitor is reported. The synthesis features a chiral auxiliary-assisted…”
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Nucleotide competing reverse transcriptase inhibitors: Discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors by James, Clint A., DeRoy, Patrick, Duplessis, Martin, Edwards, Paul J., Halmos, Teddy, Minville, Joannie, Morency, Louis, Morin, Sébastien, Simoneau, Bruno, Tremblay, Martin, Bethell, Richard, Cordingley, Michael, Duan, Jianmin, Lamorte, Louie, Pelletier, Alex, Rajotte, Daniel, Salois, Patrick, Tremblay, Sonia, Sturino, Claudio F.

“…A HTS screen led to the identification of a benzofurano[3,2-d]pyrimidin-2-one core structure which upon further optimization resulted in 1 as a potent HIV-1…”
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Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors by Tremblay, Martin, Bethell, Richard C., Cordingley, Michael G., DeRoy, Patrick, Duan, Jianmin, Duplessis, Martin, Edwards, Paul J., Faucher, Anne-Marie, Halmos, Ted, James, Clint A., Kuhn, Cyrille, Lacoste, Jean-Éric, Lamorte, Louie, LaPlante, Steven R., Malenfant, Éric, Minville, Joannie, Morency, Louis, Morin, Sébastien, Rajotte, Daniel, Salois, Patrick, Simoneau, Bruno, Tremblay, Sonia, Sturino, Claudio F.

“…Screening of our sample collection led to the identification of a set of benzofurano[3,2-d]pyrimidine-2-one hits acting as nucleotide-competing HIV-1 reverse…”
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Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: In vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors by Sturino, Claudio F., Bousquet, Yves, James, Clint A., DeRoy, Patrick, Duplessis, Martin, Edwards, Paul J., Halmos, Ted, Minville, Joannie, Morency, Louis, Morin, Sébastien, Thavonekham, Bounkham, Tremblay, Martin, Duan, Jianmin, Ribadeneira, Maria, Garneau, Michel, Pelletier, Alex, Tremblay, Sonia, Lamorte, Louie, Bethell, Richard, Cordingley, Michael G., Rajotte, Daniel, Simoneau, Bruno

“…Recently, a new class of HIV reverse transcriptase (HIV-RT) inhibitors has been reported. The novel mechanism of inhibition by this class involves competitive…”
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Efficient preparation of chiral non-racemic sulfur compounds by Minville, Joannie, Girardin, Mélina, Spino, Claude

“…p-Menthane-3-carboxaldehyde serves as an efficient chiral auxiliary in the preparation of chiral non-racemic S-alkylthiocarbamates or S-dithiocarbonates via…”
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Cleavage of a chiral auxiliary using RCM on an especially sterically crowded alkene: Syntheses of chiral carbo- and heterocycles by Spino, Claude, Boisvert, Luc, Douville, Jasmin, Roy, Stéphanie, Lauzon, Sophie, Minville, Joannie, Gagnon, David, Beaumier, Francis, Chabot, Christine

“…RCM is used to cleave a chiral auxiliary and generate carbo- and heterocycles directly. The alkene bearing the auxiliary has an uncommon steric demand…”
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Formation stéréosélective de carbones chiraux tertiaires et quaternaires portant un soufre par réarrangement sigmatropique [3,3] by Minville, Joannie

“…Le premier chapitre de ce mémoire décrit la préparation stéréosélective d'alcools allyliques utilisant un auxiliaire chiral dérivé du menthol. L'utilisation de…”
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