Search Results - "Mintzer, Meredith"

Nonviral Vectors for Gene Delivery by Mintzer, Meredith A, Simanek, Eric E

“…Nonviral sectors for gene delivery are examined. The use of lipid-based vectors and polymeric vectors are the focus of the research…”
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Biomedical applications of dendrimers: a tutorial by Mintzer, Meredith A, Grinstaff, Mark W

“…Since their development in the mid-80s, dendrimers have become prominent synthetic macromolecules in the field of biomedical science. This tutorial review…”
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Exploiting Dendrimer Multivalency To Combat Emerging and Re-Emerging Infectious Diseases by Mintzer, Meredith A, Dane, Eric L, O’Toole, George A, Grinstaff, Mark W

“…The emergence and re-emergence of bacterial strains that are resistant to current antibiotics reveal the clinical need for new agents that possess…”
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Computational Insights into the Interactions between DNA and siRNA with “Rigid” and “Flexible” Triazine Dendrimers by Pavan, Giovanni M, Mintzer, Meredith A, Simanek, Eric E, Merkel, Olivia M, Kissel, Thomas, Danani, Andrea

“…In this study, simulation challenges intuitive models of “flexible” and “rigid” generation two triazine dendrimers as it pertains to solution conformation and…”
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Triazine Dendrimers as Nonviral Vectors for in Vitro and in Vivo RNAi: The Effects of Peripheral Groups and Core Structure on Biological Activity by Merkel, Olivia M, Mintzer, Meredith A, Librizzi, Damiano, Samsonova, Olga, Dicke, Tanja, Sproat, Brian, Garn, Holger, Barth, Peter J, Simanek, Eric E, Kissel, Thomas

“…A family of triazine dendrimers, differing in their core flexibility, generation number, and surface functionality, was prepared and evaluated for its ability…”
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Triazine Dendrimers as Nonviral Gene Delivery Systems: Effects of Molecular Structure on Biological Activity by Merkel, Olivia M., Mintzer, Meredith A., Sitterberg, Johannes, Bakowsky, Udo, Simanek, Eric E., Kissel, Thomas

“…A family of generation 1, 2, and 3 triazine dendrimers differing in their core flexibility was prepared and evaluated for their ability to accomplish gene…”
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Synthesis of Odd Generation Triazine Dendrimers Using a Divergent, Macromonomer Approach by Lim, Jongdoo, Mintzer, Meredith A, Perez, Lisa M, Simanek, Eric E

“…Using a macromonomer, first, third, and fifth generation triazine dendrimers can be prepared using a divergent approach. The nine-step process to the fifth…”
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The 8 year thicket of triazine dendrimers: strategies, targets and applications by Simanek, Eric E., Abdou, Hanan, Lalwani, Sanjiv, Lim, Jongdoo, Mintzer, Meredith, Venditto, Vincent J., Vittur, Brandon

“… The diversity communicated by these groups yields dendrimers ranging from those with a common surface to examples where two groups were presented to those…”
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Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems by Merkel, Olivia M., Zheng, Mengyao, Mintzer, Meredith A., Pavan, Giovanni M., Librizzi, Damiano, Maly, Marek, Höffken, Helmut, Danani, Andrea, Simanek, Eric E., Kissel, Thomas

“…This study aimed to identify suitable siRNA delivery systems based on flexible generation 2–4 triazine dendrimers by correlating physico-chemical and…”
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Divergent synthesis of triazine dendrimers using a trimethylene-dipiperidine linker that increases efficiency, simplifies analysis, and improves product solubility by Mintzer, Meredith A., Perez, Lisa M., Simanek, Eric E.

“…To combine benefits stemming from the high nucleophilicity of piperidine and the flexibility afforded by aliphatic triamine linkers, a…”
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Perfectly shaped siRNA delivery by Merkel, Olivia M, Mintzer, Meredith A, Simanek, Eric E, Kissel, Thomas

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Triazine dendrimers as non-viral gene delivery systems: Effects of molecular structure on biological activity by Merkel, Olivia M., Mintzer, Meredith A., Sitterberg, Johannes, Bakowsky, Udo, Simanek, Eric E., Kissel, Thomas

“…A family of generation one, two and three triazine dendrimers differing in their core flexibility was prepared and evaluated for their ability to accomplish…”
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Triazine dendrimers as non-viral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity by Merkel, Olivia M., Mintzer, Meredith A., Librizzi, Damiano, Samsonova, Olga, Dicke, Tanja, Sproat, Brian, Garn, Holger, Barth, Peter J., Simanek, Eric E., Kissel, Thomas

“…A family of triazine dendrimers, differing in their core flexibility, generation number, and surface functionality, was prepared and evaluated for its ability…”
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An Evidence-Based Systematic Review of Active Hexose Correlated Compound (AHCC) by the Natural Standard Research Collaboration by Ulbricht, Catherine, Brigham, Ashley, Bryan, J. Kathryn, Catapang, Marisa, Chowdary, Divya, Costa, Dawn, Culwell, Samantha, D'Auria, Denise, Giese, Nicole, Iovin, Ramon, Isaac, Richard, Juturu, Vijaya, Liu, Angela, Mintzer, Meredith, Rusie, Erica, Shaffer, Michael, Windsor, Regina C.

“…ABSTRACTAn evidence-based systematic review of active hexose correlated compound (AHCC) by the Natural Standard Research Collaboration consolidates the safety…”
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An Evidence-Based Systematic Review of Vanadium by the Natural Standard Research Collaboration by Ulbricht, Catherine, Chao, Wendy, Costa, Dawn, Culwell, Samantha, Eichelsdoerfer, Petra, Flanagan, Kelly, Guilford, Jackie, Higdon, Elizabeth R.B., Isaac, Richard, Mintzer, Meredith, Rusie, Erica, Serrano, Jill M. Grimes, Windsor, Regina C., Woods, Jen, Zhou, Sara

“…ABSTRACTAn evidence-based systematic review of vanadium by the Natural Standard Research Collaboration consolidates the safety and efficacy data available in…”
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The design and evaluation of triazine dendrimers for gene delivery by Mintzer, Meredith Ann

“…The interest in using gene therapy to target a variety of both inherited and acquired diseases has intensified over the last two decades. Because free DNA is…”
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