Search Results - "Minowa‐Nozawa, Atsuko"
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TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy
Published in Nature communications (07-02-2020)“…Invading microbial pathogens can be eliminated selectively by xenophagy. Ubiquitin-mediated autophagy receptors are phosphorylated by TANK-binding kinase 1…”
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LAMTOR2/LAMTOR1 complex is required for TAX1BP1‐mediated xenophagy
Published in Cellular microbiology (01-04-2019)“…Xenophagy, also known as antibacterial autophagy, plays a role in host defence against invading pathogens such as Group A Streptococcus (GAS) and Salmonella…”
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Rab35 GTPase recruits NDP52 to autophagy targets
Published in The EMBO journal (15-09-2017)“…Autophagy targets intracellular molecules, damaged organelles, and invading pathogens for degradation in lysosomes. Recent studies have identified autophagy…”
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Rab35 GTPase recruits NPD52 to autophagy targets
Published in The EMBO journal (15-09-2017)“…Autophagy targets intracellular molecules, damaged organelles, and invading pathogens for degradation in lysosomes. Recent studies have identified autophagy…”
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5
Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy
Published in Nature communications (06-10-2023)“…Xenophagy, a type of selective autophagy, is a bactericidal membrane trafficking that targets cytosolic bacterial pathogens, but the membrane homeostatic…”
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Guanylate-Binding Protein 1 Regulates Infection-Induced Autophagy through TBK1 Phosphorylation
Published in Cellular microbiology (2022)“…Invading bacteria can be degraded by selective autophagy, known as xenophagy. Recent studies have shown that the recruitment of autophagy adaptor proteins such…”
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Rab35 GTPase recruits NDP52 to autophagy targets
Published in The EMBO journal (15-11-2017)Get full text
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The intracellular microbial sensor NLRP4 directs Rho-actin signaling to facilitate Group A Streptococcus-containing autophagosome-like vacuole formation
Published in Autophagy (02-11-2017)“…Xenophagy, also known as antibacterial autophagy, functions as a crucial defense system that can utilize intracellular pattern recognition sensors, such as…”
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The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes
Published in Autophagy (02-01-2017)“…Macroautophagy/autophagy plays a critical role in immunity by directly degrading invading pathogens such as Group A Streptococcus (GAS), through a process that…”
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RAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus
Published in Autophagy (04-03-2019)“…Macroautophagy/autophagy plays an important role in the immune response to invasion by intracellular pathogens such as group A Streptococcus (GAS;…”
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Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes
Published in PloS one (15-01-2016)“…Autophagy acts as a host-defense system against pathogenic microorganisms such as Group A Streptococcus (GAS). Autophagy is a membrane-mediated degradation…”
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Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection
Published in Frontiers in cellular and infection microbiology (23-12-2020)“…Bacterial autophagy-a type of macroautophagy that is also termed xenophagy-selectively targets intracellular bacteria such as group A (GAS), a ubiquitous…”
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Rab17‐mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion
Published in Cellular microbiology (01-12-2014)“…Summary Autophagy plays a crucial role in host defence by facilitating the degradation of invading bacteria such as Group A Streptococcus (GAS). GAS‐containing…”
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Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG
Published in PloS one (13-01-2017)“…Anti-apoptotic Bcl-2 and Bcl-xL are proposed to regulate starvation-induced autophagy by directly interacting with Beclin 1. Beclin 1 is also thought to be…”
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Intracellular Group A Streptococcus Induces Golgi Fragmentation To Impair Host Defenses through Streptolysin O and NAD-Glycohydrolase
Published in mBio (09-02-2021)“…Group A (GAS; ) is a major human pathogen that causes streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as…”
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NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex
Published in Frontiers in cellular and infection microbiology (14-11-2018)“…Group A (GAS) can invade epithelial cells; however, these bacteria are targeted and eventually destroyed by autophagy. Members of the Nod-like receptor (NLR)…”
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Complete Genome Sequences of Two Streptococcus suis Strains Isolated from Asymptomatic Pigs
Published in Microbiology resource announcements (19-11-2020)“…Streptococcus suis is an important zoonotic pathogen that causes major economic problems in the pig industry worldwide and serious infections in humans,…”
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Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy
Published in Autophagy (01-02-2020)“…Autophagy selectively targets invading bacteria to defend cells, whereas bacterial pathogens counteract autophagy to survive in cells. The initiation of…”
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Erratum To: Rab35 GTPase recruits NDP52 to autophagy targets
Published in The EMBO journal (15-11-2017)“…Graphical Abstract…”
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Complete genome sequence of three Staphylococcus epidermidis strains isolated from patients with skin diseases in Japan
Published in Microbiology resource announcements (20-06-2024)“…is a member of the human skin microbiota as a commensal organism but could be an important opportunistic pathogen for immunocompromised individuals. Here, we…”
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