Antibiotic Prophylaxis in Infants with Grade III, IV, or V Vesicoureteral Reflux

In a trial involving infants with grade III, IV, or V vesicoureteral reflux and no previous UTI, continuous antibiotic prophylaxis for 2 years provided a small but significant benefit in preventing a first UTI.

Saved in:

Bibliographic Details
Published in:	The New England journal of medicine Vol. 389; no. 11; pp. 987 - 997
Main Authors:	Morello, William, Baskin, Esra, Jankauskiene, Augustina, Yalcinkaya, Fatos, Zurowska, Aleksandra, Puccio, Giuseppe, Serafinelli, Jessica, La Manna, Angela, Krzemień, Grażyna, Pennesi, Marco, La Scola, Claudio, Becherucci, Francesca, Brugnara, Milena, Yuksel, Selcuk, Mekahli, Djalila, Chimenz, Roberto, De Palma, Diego, Zucchetta, Pietro, Vajauskas, Donatas, Drozdz, Dorota, Szczepanska, Maria, Caliskan, Salim, Lombet, Jacques, Minoli, Dario G., Guarino, Stefano, Gulleroglu, Kaan, Ruzgiene, Dovile, Szmigielska, Agnieszka, Barbi, Egidio, Ozcakar, Zeynep B., Kranz, Anna, Pasini, Andrea, Materassi, Marco, De Rechter, Stephanie, Ariceta, Gema, Weber, Lutz T., Marzuillo, Pierluigi, Alberici, Irene, Taranta-Janusz, Katarzyna, Caldas Afonso, Alberto, Tkaczyk, Marcin, Català, Margarita, Cabrera Sevilla, Jose E., Mehls, Otto, Schaefer, Franz, Montini, Giovanni
Format:	Journal Article Web Resource
Language:	English
Published:	United States Massachusetts Medical Society 14-09-2023
Subjects:	Anti-Bacterial Agents Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Anti-Bacterial Agents/administration & dosage/adverse effects/therapeutic use Antibiotic Prophylaxis - adverse effects Antibiotic Prophylaxis - methods Antibiotic Prophylaxis/adverse effects/methods Antibiotic resistance Antibiotics Bacterial Infections Bladder Clinical Medicine Clinical Medicine General Congenital Kidney Disease Disease prevention Drug Resistance, Bacterial - drug effects Female Glomerular filtration rate Glomerulonephritis Human health sciences Humans Infant Infants Infectious Disease Intention to Treat Analysis Kidneys Male Nephrology Pediatrics Pediatrics General Prophylaxis Pyelonephritis Pédiatrie Sciences de la santé humaine Ultrasonic imaging Urinalysis Urinary tract Urinary tract infections Urinary Tract Infections - etiology Urinary Tract Infections - microbiology Urinary Tract Infections - prevention & control Urinary Tract Infections/etiology/microbiology/prevention & control Urogenital system Urologie & néphrologie Urology & nephrology UTI Vesico-Ureteral Reflux - complications Vesico-Ureteral Reflux - drug therapy Vesico-Ureteral Reflux/complications/drug therapy
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	In a trial involving infants with grade III, IV, or V vesicoureteral reflux and no previous UTI, continuous antibiotic prophylaxis for 2 years provided a small but significant benefit in preventing a first UTI.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Undefined-1 ObjectType-Feature-3 content type line 23 scopus-id:2-s2.0-85173555774
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2300161