Search Results - "Minobe, Wayne A."

Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance by Toni, Lee S, Carroll, Ian A, Jones, Kenneth L, Schwisow, Jessica A, Minobe, Wayne A, Rodriguez, Erin M, Altman, Natasha L, Lowes, Brian D, Gilbert, Edward M, Buttrick, Peter M, Kao, David P, Bristow, Michael R

“…To investigate the biologic relevance of cross-platform concordant changes in gene expression in intact human failing/hypertrophied ventricular myocardium…”
Get full text

Impact of Neuroeffector Adrenergic Receptor Polymorphisms on Incident Ventricular Fibrillation During Acute Myocardial Ischemia by Chevalier, Philippe, Roy, Pascal, Bessière, Francis, Morel, Elodie, Ankou, Bénédicte, Morgan, Gina, Halder, Indrani, London, Barry, Minobe, Wayne A, Slavov, Dobromir, Delinière, Antoine, Bochaton, Thomas, Paganelli, Franck, Lesavre, Nathalie, Boiteux, Clément, Mansourati, Jacques, Maury, Philippe, Clerici, Gaël, Winum, Pierre François, Huebler, Sophia P, Carroll, Ian A, Bristow, Michael R

“…Background Cardiac adrenergic receptor gene polymorphisms have the potential to influence risk of developing ventricular fibrillation (VF) during…”
Get full text

Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance by Toni, Lee S, Carroll, Ian A, Jones, Kenneth L, Schwisow, Jessica A, Minobe, Wayne A, Rodriguez, Erin M, Altman, Natasha L, Lowes, Brian D, Gilbert, Edward M, Buttrick, Peter M, Kao, David P, Bristow, Michael R

“…[This corrects the article DOI: 10.1371/journal.pone.0221519.]…”
Get full text

An extensive β1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies by Tatman, Philip D, Kao, David P, Chatfield, Kathryn C, Carroll, Ian A, Wagner, Jessica A, Jonas, Eric R, Sucharov, Carmen C, Port, J David, Lowes, Brian D, Minobe, Wayne A, Huebler, Sophia P, Karimpour-Fard, Anis, Rodriguez, Erin M, Liggett, Stephen B, Bristow, Michael R

“…We investigated the extent, biologic characterization, phenotypic specificity, and possible regulation of a β1-adrenergic receptor-linked (β1-AR-linked) gene…”
Get full text

Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium by Bristow, Michael R., Zisman, Lawrence S., Altman, Natasha L., Gilbert, Edward M., Lowes, Brian D., Minobe, Wayne A., Slavov, Dobromir, Schwisow, Jessica A., Rodriguez, Erin M., Carroll, Ian A., Keuer, Thomas A., Buttrick, Peter M., Kao, David P.

“…[Display omitted] •The CoV-2 cellular receptor ACE2 and 5 proteases implicated in fusion of virus and cell membranes that are vital to cell entry were…”
Get full text

Selective downregulation of the angiotensin II AT1-receptor subtype in failing human ventricular myocardium by ASANO, K, DUTCHER, D. L, RAYNOLDS, M. V, ZISMAN, L. S, PERRYMAN, M. B, BRISTOW, M. R, PORT, J. D, MINOBE, W. A, TREMMEL, K. D, RODEN, R. L, BOHLMEYER, T. J, BUSH, E. W, JENKIN, M. J, ABRAHAM, W. T

“…The regulation of angiotensin II receptors and the two major subtypes (AT1 and AT2) in chronically failing human ventricular myocardium has not been previously…”
Get full text

Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination by Altman, Natasha L., Berning, Amber A., Saxon, Cara E., Adamek, Kylie E., Wagner, Jessica A., Slavov, Dobromir, Quaife, Robert A., Gill, Edward A., Minobe, Wayne A., Jonas, Eric R., Carroll, Ian A., Huebler, Sophia P., Raines, Joshua, Messenger, John C., Ambardekar, Amrut V., Mestroni, Luisa, Rosenberg, Rachel M., Rove, Jessica, Campbell, Thomas B., Bristow, Michael R.

“…[Display omitted] •Patients with biomarker, imaging, or electrocardiographic evidence of myocardial injury associated with recent COVID-19 infection exhibited…”
Get full text

Myocardial Gene Expression in Dilated Cardiomyopathy Treated with Beta-Blocking Agents by Lowes, Brian D, Gilbert, Edward M, Abraham, William T, Minobe, Wayne A, Larrabee, Patti, Ferguson, Debra, Wolfel, Eugene E, Lindenfeld, JoAnn, Tsvetkova, Tatiana, Robertson, Alastair D, Quaife, Robert A, Bristow, Michael R

“…Beta-blocker therapy may benefit patients with dilated cardiomyopathy. In this study, the expression of myocardial genes affecting cardiac contractility and…”
Get full text

Signaling pathways responsible for fetal gene induction in the failing human heart : Evidence for altered thyroid hormone receptor gene expression by KINUGAWA, Koichiro, MINOBE, Wayne A, WOOD, William M, RIDGWAY, E. Chester, BAXTER, John D, RIBEIRO, Ralff C. J, TAWADROUS, Magdy F, LOWES, Brian A, LONG, Carlin S, BRISTOW, Michael R

“…We have previously demonstrated that changes in myosin heavy chain (MHC) isoforms that occur in failing human hearts resemble the pattern produced in rodent…”
Get full text

Serial gene expression profiling in the intact human heart by Lowes, Brian D, Zolty, Ronald, Minobe, Wayne A, Robertson, Alastair D, Leach, Sonia, Hunter, Lawrence, Bristow, Michael R

“…In chronic heart failure due to a dilated cardiomyopathy phenotype, the molecular bases for contractile dysfunction and chamber remodeling remain largely…”
Get more information

Altered Expression of Endothelin Receptors in Failing Human Left Ventricles by Asano, Koji, Bohlmeyer, Teresa J., Westcott, Jay Y., Zisman, Lawrence, Kinugawa, Koichiro, Good, Matthew, Minobe, Wayne A., Roden, Robert, Wolfel, Eugene E., Lindenfeld, Joann, David Port, J., Perryman, M.Benjamin, Clevel, Joseph, Lowes, Brian D., Bristow, Michael R.

“…K. Asano, T. J. Bohlmeyer, J. Y. Westcott, L. S Zisman, K. Kinugawa, M. Good, W. A. Minobe, R. L. Roden, E. E. Wolfel, J. Lindenfeld, J. D. Port, M. B…”
Get full text

Mediation of subacute anthracycline cardiotoxicity in rabbits by cardiac histamine release by Bristow, M R, Kantrowitz, N E, Harrison, W D, Minobe, W A, Sageman, W S, Billingham, M E

“…We tested the hypothesis that cardiac histamine release mediates subacute doxorubicin (DXR) cardiotoxicity in rabbits. New Zealand white rabbits given DXR 20…”
Get more information

Reduced β1 receptor messenger RNA abundance in the failing human heart by BRISTOW, M. R, MINOBE, W. A, RAYNOLDS, M. V, PORT, J. D, RANDY RASMUSSEN, RAY, P. E, FELDMAN, A. M

Get full text

Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway by Pende, A, Tremmel, K D, DeMaria, C T, Blaxall, B C, Minobe, W A, Sherman, J A, Bisognano, J D, Bristow, M R, Brewer, G, Port, J

“…In both cell culture based model systems and in the failing human heart, beta-adrenergic receptors ( beta-AR) undergo agonist-mediated down-regulation. This…”
Get full text

β-blocker related improvement in exercise capacity is associated with increased expression of SR Ca+2-ATPase by Lowes, Brian D., Wolfel, Eugene, Gilbert, Edward M., Abraham, William T., Ferguson, Debbie, Robertson, Alastair D., Minobe, Wayne A., Bristow, Michael R.

Get full text

Differential regulation of β1 and β2 andrenergic receptors and mRNA by non-selective β agonist exposure in preparations of isolation human heart by Roden, Robert L., Minobe, Wayne A., Dutcher, Darrin L., Tremmel, Kelli D., Port, J.David, Bristow, Michael R.

Get full text

Regulation of the mRNA-binding Protein AUF1 by Activation of the -Adrenergic Receptor Signal Transduction Pathway by Aldo Pende, Kelli D. Tremmel, Christine T. DeMaria, Burns C. Blaxall, Wayne A. Minobe, Jonathan A. Sherman, John D. Bisognano, Michael R. Bristow, Gary Brewer, J. David Port

“…In both cell culture based model systems and in the failing human heart, β-adrenergic receptors (β-AR) undergo agonist-mediated down-regulation. This…”
Get full text

Selective Downregulation of the Angiotensin II AT 1 -Receptor Subtype in Failing Human Ventricular Myocardium by Asano, Koji, Dutcher, Darrin L., Port, J. David, Minobe, Wayne A., Tremmel, Kelli D., Roden, Robert L., Bohlmeyer, Teresa J., Bush, Erik W., Jenkin, Matthew J., Abraham, William T., Raynolds, Mary V., Zisman, Lawrence S., Perryman, M. Benjamin, Bristow, Michael R.

“…Background The regulation of angiotensin II receptors and the two major subtypes (AT 1 and AT 2 ) in chronically failing human ventricular myocardium has not…”
Get full text

Histamine-mediated myocardial damage in rabbits by Kantrowitz, N E, Bristow, M R, Minobe, W A, Billingham, M E, Harrison, D C

Get more information