Search Results - "Minkowitz, S"

Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting by Gan, Tong J., Belani, Kumar G., Bergese, Sergio, Chung, Frances, Diemunsch, Pierre, Habib, Ashraf S., Jin, Zhaosheng, Kovac, Anthony L., Meyer, Tricia A., Urman, Richard D., Apfel, Christian C., Ayad, Sabry, Beagley, Linda, Candiotti, Keith, Englesakis, Marina, Hedrick, Traci L., Kranke, Peter, Lee, Samuel, Lipman, Daniel, Minkowitz, Harold S., Morton, John, Philip, Beverly K.

“…This consensus statement presents a comprehensive and evidence-based set of guidelines for the care of postoperative nausea and vomiting (PONV) in both adult…”
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A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Repeat-Dose Study of Two Intravenous Acetaminophen Dosing Regimens for the Treatment of Pain After Abdominal Laparoscopic Surgery by Wininger, Steven J., MD, Miller, Howard, MD, Minkowitz, Harold S., MD, Royal, Mike A., MD, JD, MBA, Ang, Robert Y., MD, Breitmeyer, James B., MD, PhD, Singla, Neil K., MD

“…Abstract Background Intravenous acetaminophen has been approved in Europe and elsewhere for the treatment of acute pain and fever, and was recently approved by…”
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A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (μ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty by Singla, Neil, Minkowitz, Harold S, Soergel, David G, Burt, David A, Subach, Ruth Ann, Salamea, Monica Y, Fossler, Michael J, Skobieranda, Franck

“…Oliceridine (TRV130), a novel μ-receptor G-protein pathway selective (μ-GPS) modulator, was designed to improve the therapeutic window of conventional opioids…”
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Sufentanil Sublingual Tablet System for the Management of Postoperative Pain after Knee or Hip Arthroplasty: A Randomized, Placebo-controlled Study by Jove, Maurice, Griffin, David W, Minkowitz, Harold S, Ben-David, Bruce, Evashenk, Mark A, Palmer, Pamela P

“…BACKGROUND:Complications with IV patient-controlled analgesia include programming errors, invasive access, and impairment of mobility. This study evaluated an…”
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Adverse drug events among patients receiving postsurgical opioids in a large health system: Risk factors and outcomes by MINKOWITZ, HAROLD S, GRUSCHKUS, STEPHEN K, SHAH, MANAN, RAJU, ADITYA

“…PURPOSEResults of a study of postsurgical opioid-related adverse drug events (ORADEs) within a large health system are reported. METHODSIn a retrospective…”
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A review of sufentanil and the sufentanil sublingual tablet system for acute moderate to severe pain by Minkowitz, Harold S

“…The sufentanil sublingual tablet system (SSTS) is a novel patient-controlled analgesia (PCA) system that is pending approval from the US FDA for the management…”
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Sufentanil sublingual tablet 30 mcg for moderate-to-severe acute pain in the ED by Miner, James R., Rafique, Zubaid, Minkowitz, Harold S., DiDonato, Karen P., Palmer, Pamela P.

“…BackgroundPharmacological properties of the sufentanil sublingual tablet 30mcg (SST 30mcg) could offer potential analgesic advantages in settings requiring…”
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Safety and Efficacy of Bupivacaine HCl Collagen-Matrix Implant (INL-001) in Open Inguinal Hernia Repair: Results from Two Randomized Controlled Trials by Velanovich, Vic, Rider, Paul, Deck, Kenneth, Minkowitz, Harold S., Leiman, David, Jones, Nigel, Niebler, Gwendolyn

“…Introduction Surgical site infiltration with bupivacaine results in short-lived analgesia. The MATRIX-1 and MATRIX-2 studies examined the efficacy and safety…”
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The role of sublingual sufentanil nanotabs for pain relief by Minkowitz, Harold S, Candiotti, Keith

“…The authors discuss a novel patient controlled analgesia system utilizing a preprogrammed device that delivers a small submucosal tablet of sufentanil. This…”
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Sufentanil Sublingual Tablet System for the Management of Postoperative Pain Following Open Abdominal Surgery: A Randomized, Placebo-Controlled Study by Ringold, Forrest G, Minkowitz, Harold S, Gan, Tong Joo, Aqua, Keith A, Chiang, Yu-kun, Evashenk, Mark A, Palmer, Pamela P

“…BACKGROUND AND OBJECTIVESThis study evaluates the efficacy and safety of a sufentanil sublingual tablet system (SSTS) for the management of postoperative pain…”
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Sufentanil Sublingual Tablet System vs. Intravenous Patient-Controlled Analgesia with Morphine for Postoperative Pain Control: A Randomized, Active-Comparator Trial by Melson, Timothy I., Boyer, David L., Minkowitz, Harold S., Turan, Alparslan, Chiang, Yu-Kun, Evashenk, Mark A., Palmer, Pamela P.

“…Background Problems with intravenous patient‐controlled analgesia (IV PCA) are well known, including invasive route of delivery and pump programming errors…”
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Sufentanil Sublingual Tablet 30 mcg for the Management of Pain Following Abdominal Surgery: A Randomized, Placebo‐Controlled, Phase‐3 Study by Minkowitz, Harold S., Leiman, David, Melson, Timothy, Singla, Neil, DiDonato, Karen P., Palmer, Pamela P.

“…Background Results from a phase‐3, prospective, randomized, double‐blind, placebo‐controlled trial evaluating sufentanil sublingual tablet 30 mcg (SST) for the…”
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Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial by Rawal, Narinder, Viscusi, Eugene, Peloso, Paul M, Minkowitz, Harold S, Chen, Liang, Shah, Sandhya, Mehta, Anish, Chitkara, Denesh K, Curtis, Sean P, Papanicolaou, Dimitris A

“…Optimal postoperative pain management is important to ensure patient comfort and early mobilization. In this double-blind, placebo- and active-controlled,…”
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ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy by Bergese, Sergio D, Brzezinski, Marek, Hammer, Gregory B, Beard, Timothy L, Pan, Peter H, Mace, Sharon E, Berkowitz, Richard D, Cochrane, Kristina, Wase, Linda, Minkowitz, Harold S, Habib, Ashraf S

“…Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous…”
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A Novel Methodology for Applying Multivoxel MR Spectroscopy to Evaluate Convection-Enhanced Drug Delivery in Diffuse Intrinsic Pontine Gliomas by Guisado, D I, Singh, R, Minkowitz, S, Zhou, Z, Haque, S, Peck, K K, Young, R J, Tsiouris, A J, Souweidane, M M, Thakur, S B

“…Diffuse intrinsic pontine gliomas are inoperable high-grade gliomas with a median survival of less than 1 year. Convection-enhanced delivery is a promising…”
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Comparison of the Efficacy and Safety of Dual-Opioid Treatment With Morphine Plus Oxycodone Versus Oxycodone/Acetaminophen for Moderate to Severe Acute Pain After Total Knee Arthroplasty by Richards, Patricia, MD, PhD, Gimbel, Joseph S., MD, Minkowitz, Harold S., MD, Kelen, Robin, MS, Stern, Warren, PhD

“…Abstract Background In acute pain models, coadministration of low doses of morphine and oxycodone markedly enhanced analgesia relative to either opioid given…”
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Real-world experience with neuromuscular blockade reversal by Groudine, Scott B., Minkowitz, Harold S., Valentine, Danny L.

“…Neuromuscular blocking agents are used in many surgical procedures and have enabled new surgical advances. The expanded landscape of neuromuscular blockade…”
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Pharmacokinetics and Safety of INL-001 (Bupivacaine HCl) Implants Compared with Bupivacaine HCl Infiltration After Open Unilateral Inguinal Hernioplasty by Leiman, David, Niebler, Gwendolyn, Minkowitz, Harold S.

“…Introduction Surgical site infiltration with bupivacaine HCl results in short-lived analgesia for postsurgical pain and carries the risk of systemic…”
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Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial by Shafer, Steven L, Teichman, Sam L, Gottlieb, Ira J, Singla, Neil, Minkowitz, Harold S, Leiman, David, Vaughn, Benjamin, Donovan, John F

“…Nonopioid management of postsurgical pain remains a major unmet need. Few studies have evaluated transient receptor potential vanilloid subfamily member 1…”
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A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of a bupivacaine hydrochloride implant in patients undergoing abdominoplasty by Beaton, Alina C, Solanki, Daneshvari, Salazar, Hernan, Folkerth, Steve, Singla, Neil, Minkowitz, Harold S, Leiman, David, Vaughn, Ben, Skuban, Nina, Niebler, Gwendolyn

“…IntroductionSurgical site infiltration with bupivacaine hydrochloride (HCl) is a standard element of postoperative analgesia for soft tissue surgeries, but…”
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