Search Results - "Minic, Angela"

Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension by Galambos, Csaba, Minic, Angela D, Bush, Douglas, Nguyen, Dominique, Dodson, Blair, Seedorf, Gregory, Abman, Steven H

“…Infants with Down syndrome (DS) or Trisomy 21, are at high risk for developing pulmonary arterial hypertension (PAH), but mechanisms that increase…”
Get full text

A platform-independent framework for phenotyping of multiplex tissue imaging data by Ahmadian, Mansooreh, Rickert, Christian, Minic, Angela, Wrobel, Julia, Bitler, Benjamin G, Xing, Fuyong, Angelo, Michael, Hsieh, Elena W Y, Ghosh, Debashis, Jordan, Kimberly R

“…Multiplex imaging is a powerful tool to analyze the structural and functional states of cells in their morphological and pathological contexts. However,…”
Get full text

The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides by Kruglov, Oleg, Johnson, Lisa D. S., Minic, Angela, Jordan, Kimberly, Uger, Robert A., Wong, Mark, Sievers, Eric L., Shou, Yaping, Akilov, Oleg E.

“…CD47 is frequently overexpressed on tumor cells and is an attractive therapeutic target. The mechanism by which anti-CD47 immunotherapy eliminates cutaneous…”
Get full text

Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity by Guth, Amanda, Monk, Emily, Agarwal, Rajesh, Bergman, Bryan C, Zemski-Berry, Karin A, Minic, Angela, Jordan, Kimberly, Schlaepfer, Isabel R

“…Lipid catabolism represents an Achilles heel in prostate cancer (PCa) that can be exploited for therapy. CPT1A regulates the entry of fatty acids into the…”
Get full text

Potassium dependent rescue of a myopathy with core-like structures in mouse by Hanson, M Gartz, Wilde, Jonathan J, Moreno, Rosa L, Minic, Angela D, Niswander, Lee

“…Myopathies decrease muscle functionality. Mutations in ryanodine receptor 1 (RyR1) are often associated with myopathies with microscopic core-like structures…”
Get full text

Ghrelin is dispensable for embryonic pancreatic islet development and differentiation by Hill, Jonathon T., Mastracci, Teresa L., Vinton, Carol, Doyle, Michelle L., Anderson, Keith R., Loomis, Zoe L., Schrunk, Jessica M., Minic, Angela D., Prabakar, Kamalaveni R., Pugliese, Alberto, Sun, Yuxian, Smith, Roy G., Sussel, Lori

“…Ghrelin is a peptide hormone that has been implicated in the regulation of food intake and energy homeostasis. Ghrelin is predominantly produced in the…”
Get full text

The Capacity of the Ovarian Cancer Tumor Microenvironment to Integrate Inflammation Signaling Conveys a Shorter Disease-free Interval by Jordan, Kimberly R, Sikora, Matthew J, Slansky, Jill E, Minic, Angela, Richer, Jennifer K, Moroney, Marisa R, Hu, Junxiao, Wolsky, Rebecca J, Watson, Zachary L, Yamamoto, Tomomi M, Costello, James C, Clauset, Aaron, Behbakht, Kian, Kumar, T Rajendra, Bitler, Benjamin G

“…Ovarian cancer has one of the highest deaths to incidence ratios across all cancers. Initial chemotherapy is effective, but most patients develop…”
Get full text

Abstract 5305: Characterization of the ovarian tumor transcriptome and microenvironment in pre and post-chemotherapy treated patients by Jordan, Kimberly R., Slansky, Jill, Minic, Angela, Richer, Jennifer K., Costello, James C., Clauset, Aaron J., Kumar, Rajendra T., Behbakht, Kian, Sikora, Matthew J., Bitler, Benjamin G.

“…Abstract Purpose: Ovarian cancer has one of the highest deaths to incidence ratios across all cancers. Initial chemotherapy is typically effective, but most…”
Get full text

Abstract 6647: Sensitizing microsatellite stable colorectal cancer to immune checkpoint therapy utilizing Wnt pathway inhibition by Bagby, Stacey M., Hartman, Sarah J., Navarro, Natalie M., Yacob, Betelehem W., Shulman, Jeremy, Barkow, Jessica, Lieu, Christopher H., Davis, S. Lindsey, Leal, Alexis D., Messersmith, Wells A., Minic, Angela, Jordan, Kimberly R., Lang, Julie, Pitts, Todd M.

“…Abstract Immunotherapies that target immune regulatory checkpoints such as CTLA-4 and PD-1 are widely used among many cancer types and have shown positive…”
Get full text

Clinical Response to Anti-CD47 Immunotherapy Is Associated with Rapid Reduction of Exhausted Bystander CD4+ BTLA+ T Cells in Tumor Microenvironment of Mycosis Fungoides by Jiang, Tony T., Kruglov, Oleg, Lin, Gloria H. Y., Minic, Angela, Jordan, Kimberly, Uger, Robert A., Wong, Mark, Shou, Yaping, Akilov, Oleg E.

“…Cancer progression in mycosis fungoides, the most common form of cutaneous T-cell lymphoma, occurs in a predictable, sequential pattern that starts from…”
Get full text

Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine by Desai, Shailey, Loomis, Zoe, Pugh-Bernard, Aimee, Schrunk, Jessica, Doyle, Michelle J., Minic, Angela, McCoy, Erica, Sussel, Lori

“…Nkx2.2 is a homeodomain-containing transcription factor essential for pancreatic islet cell specification. In this study we investigate the role of Nkx2.2…”
Get full text

The kinome of lung branching morphogenesis — A systems approach to identify phosphoregulators of mouse lung development by Schnatwinkel, Carsten, Minic, Angela, Niswander, Lee

Get full text

Internal initiation of translation of the TrkB mRNA is mediated by multiple regions within the 5′ leader by Dobson, Tara, Minic, Angela, Nielsen, Kirsten, Amiott, Elizabeth, Krushel, Les

“…Translational regulation of the dendritically localized mRNA encoding for the neurotrophin receptor TrkB has important ramifications for synaptic function. We…”
Get full text