Search Results - "Mineur, S."

Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior by Picciotto, Marina R., Higley, Michael J., Mineur, Yann S.

“…Acetylcholine in the brain alters neuronal excitability, influences synaptic transmission, induces synaptic plasticity, and coordinates firing of groups of…”
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Origin and Function of Stress-Induced IL-6 in Murine Models by Qing, Hua, Desrouleaux, Reina, Israni-Winger, Kavita, Mineur, Yann S., Fogelman, Nia, Zhang, Cuiling, Rashed, Saleh, Palm, Noah W., Sinha, Rajita, Picciotto, Marina R., Perry, Rachel J., Wang, Andrew

“…Acute psychological stress has long been known to decrease host fitness to inflammation in a wide variety of diseases, but how this occurs is incompletely…”
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Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis by Mineur, Yann S, Picciotto, Marina R

“…There is a well-established connection between smoking and depression. Depressed individuals are over-represented among smokers, and ex-smokers often…”
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Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states by Picciotto, Marina R., Lewis, Alan S., van Schalkwyk, Gerrit I., Mineur, Yann S.

“…The co-morbidity between smoking and mood disorders is striking. Preclinical and clinical studies of nicotinic effects on mood, anxiety, aggression, and…”
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Sex differences in stress-related alcohol use by Peltier, MacKenzie R., Verplaetse, Terril L., Mineur, Yann S., Petrakis, Ismene L., Cosgrove, Kelly P., Picciotto, Marina R., McKee, Sherry A.

“…Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten years relative to a 35% increase in men. This substantive increase in…”
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Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior by Mineur, Yann S., Obayemi, Adetokunbo, Wigestrand, Mattis B., Fote, Gianna M., Calarco, Cali A., Li, Alice M., Picciotto, Marina R.

“…Symptoms of depression can be induced in humans through blockade of acetylcholinesterase (AChE) whereas antidepressant-like effects can be produced in animal…”
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Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice by Mineur, Yann S., Belzung, Catherine, Crusio, Wim E.

“…The widely accepted stress-diathesis hypothesis of depression postulates that genetic factors contribute to biological vulnerability. Based on this concept,…”
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Molecules and circuits involved in nicotine addiction: The many faces of smoking by Picciotto, Marina R., Mineur, Yann S.

“…Tobacco smoking in humans is one of the most persistent and widespread addictions and is driven by nicotine in tobacco smoke. Over the last several decades,…”
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An Instructive Role for Patterned Spontaneous Retinal Activity in Mouse Visual Map Development by Xu, Hong-ping, Furman, Moran, Mineur, Yann S., Chen, Hui, King, Sarah L., Zenisek, David, Zhou, Z. Jimmy, Butts, Daniel A., Tian, Ning, Picciotto, Marina R., Crair, Michael C.

“…Complex neural circuits in the mammalian brain develop through a combination of genetic instruction and activity-dependent refinement. The relative role of…”
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Nicotine Decreases Food Intake Through Activation of POMC Neurons by Mineur, Yann S., Abizaid, Alfonso, Rao, Yan, Salas, Ramiro, DiLeone, Ralph J., Gündisch, Daniela, Diano, Sabrina, De Biasi, Mariella, Horvath, Tamas L., Gao, Xiao-Bing, Picciotto, Marina R.

“…Smoking decreases appetite, and smokers often report that they smoke to control their weight. Understanding the neurobiological mechanisms underlying the…”
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Origin and Function of Stress-Induced IL-6 in Murine Models by Qing, Hua, Desrouleaux, Reina, Israni-Winger, Kavita, Mineur, Yann S., Fogelman, Nia, Zhang, Cuiling, Rashed, Saleh, Palm, Noah W., Sinha, Rajita, Picciotto, Marina R., Perry, Rachel J., Wang, Andrew

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CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory by Park, Joongkyu, Chávez, Andrés E., Mineur, Yann S., Morimoto-Tomita, Megumi, Lutzu, Stefano, Kim, Kwang S., Picciotto, Marina R., Castillo, Pablo E., Tomita, Susumu

“…Protein phosphorylation is an essential step for the expression of long-term potentiation (LTP), a long-lasting, activity-dependent strengthening of synaptic…”
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Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress by Mineur, Yann S, Fote, Gianna M, Blakeman, Sam, Cahuzac, Emma L M, Newbold, Sylvia A, Picciotto, Marina R

“…Electrophysiological and neurochemical studies implicate cholinergic signaling in the basolateral amygdala (BLA) in behaviors related to stress. Both animal…”
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Pathophysiology of nAChRs: Limbic circuits and related disorders by Mineur, Yann S., Soares, Alexa R., Etherington, Ian M., Abdulla, Zuhair I., Picciotto, Marina R.

“…Human epidemiological studies have identified links between nicotine intake and stress disorders, including anxiety, depression and PTSD. Here we review the…”
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Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency by Crouse, Richard B, Kim, Kristen, Batchelor, Hannah M, Girardi, Eric M, Kamaletdinova, Rufina, Chan, Justin, Rajebhosale, Prithviraj, Pittenger, Steven T, Role, Lorna W, Talmage, David A, Jing, Miao, Li, Yulong, Gao, Xiao-Bing, Mineur, Yann S, Picciotto, Marina R

“…The basolateral amygdala (BLA) is critical for associating initially neutral cues with appetitive and aversive stimuli and receives dense neuromodulatory…”
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Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction by Mineur, Yann S., Picciotto, Marina R.

“…Human twin studies have suggested that there is a substantial genetic component underlying nicotine dependence, ongoing smoking and ability to quit. Similarly,…”
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Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamus by Calarco, Cali A., Li, Zhiying, Taylor, Seth R., Lee, Somin, Zhou, Wenliang, Friedman, Jeffrey M., Mineur, Yann S., Gotti, Cecilia, Picciotto, Marina R.

“…Nicotine, acting through nicotinic acetylcholine receptors (nAChRs), increases the firing rate of both orexigenic agouti‐related peptide (AgRP) and…”
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Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice by Mineur, Yann S., Somenzi, Oli, Picciotto, Marina R.

“…The nicotine in tobacco is thought to modulate neuronal systems regulating mood. Moreover, it appears possible that blockade rather than activation of…”
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Antidepressant-Like Effects of Ceftriaxone in Male C57BL/6J Mice by Mineur, Yann S, Picciotto, Marina R, Sanacora, Gerard

“…Background Excessive glutamatergic neurotransmission is hypothesized to be associated with depressive-like behaviors and possibly major depressive disorder…”
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Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains by Malki, Karim, Mineur, Yann S, Tosto, Maria Grazia, Campbell, James, Karia, Priya, Jumabhoy, Irfan, Sluyter, Frans, Crusio, Wim E, Schalkwyk, Leonard C

“…BALB/cJ is a strain susceptible to stress and extremely susceptible to a defective hedonic impact in response to chronic stressors. The strain offers much…”
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