Search Results - "Minchella, Ida"

Corrigendum: Aromatase inhibitors: the journey from the state of the art to clinical open questions by Generali, Daniele, Berardi, Rossana, Caruso, Michele, Cazzaniga, Marina, Garrone, Ornella, Minchella, Ida, Paris, Ida, Pinto, Carmine, De Placido, Sabino

“…[This corrects the article DOI: 10.3389/fonc.2023.1249160.]…”
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Aromatase inhibitors: the journey from the state of the art to clinical open questions by Generali, Daniele, Berardi, Rossana, Caruso, Michele, Cazzaniga, Marina, Garrone, Ornella, Minchella, Ida, Paris, Ida, Pinto, Carmine, De Placido, Sabino

“…Breast cancer is a major cause of death among females. Great advances have been made in treating this disease, and aromatase inhibitors (AIs) have been…”
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Strategies to modulate the immune system in breast cancer: checkpoint inhibitors and beyond by Migali, Cristina, Milano, Monica, Trapani, Dario, Criscitiello, Carmen, Esposito, Angela, Locatelli, Marzia, Minchella, Ida, Curigliano, Giuseppe

“…Is breast cancer (BC) immunogenic? Many data suggest that it is. Many observations demonstrated the prognostic role of tumor-infiltrating lymphocytes (TILs) in…”
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Biopsy confirmation of metastatic sites in breast cancer patients: clinical impact and future perspectives by Criscitiello, Carmen, André, Fabrice, Thompson, Alastair M, De Laurentiis, Michele, Esposito, Angela, Gelao, Lucia, Fumagalli, Luca, Locatelli, Marzia, Minchella, Ida, Orsi, Franco, Goldhirsch, Aron, Curigliano, Giuseppe

“…Determination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is…”
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Immune approaches to the treatment of breast cancer, around the corner? by Criscitiello, Carmen, Esposito, Angela, Gelao, Lucia, Fumagalli, Luca, Locatelli, Marzia, Minchella, Ida, Adamoli, Laura, Goldhirsch, Aron, Curigliano, Giuseppe

“…Immunotherapy for the treatment of breast cancer can be categorized as either (a) specific stimulation of the immune system by active immunization, with cancer…”
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530 Clinicopathologic features and outcome of patients with microsatellite instable (MSI-H) cancer treated in a Phase I unit by Crimini, Edoardo, Repetto, Matteo, Esposito, Angela, Belli, Carmen, Criscitiello, Carmen, Locatelli, Marzia, Minchella, Ida, Nicolo’, Eleonora, Bielo, Luca Boscolo, Castellano, Grazia, Pellizzari, Gloria, Morganti, Stefania, Maria Berton Giachetti, Pier Paolo, Antonarelli, Gabriele, Ascione, Liliana, Valenza, Carmine, Tarantino, Paolo, Salimbeni, Beatrice Taurelli, Curigliano, Giuseppe

“…BackgroundMSI-H derives from genomic hypermutability due to deficient mismatch repair (dMMR) function. dMMR can occur for epigenetic silencing or mutations in…”
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Entinostat for the treatment of breast cancer by Trapani, Dario, Esposito, Angela, Criscitiello, Carmen, Mazzarella, Luca, Locatelli, Marzia, Minchella, Ida, Minucci, Saverio, Curigliano, Giuseppe

“…Breast cancer accounts for 29% of malignant tumors. It is an heterogenous disease covering a spectrum of different molecular subtypes. Epigenetic aberrations…”
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Monitoring tumor-derived cell-free DNA in patients with solid tumors: Clinical perspectives and research opportunities by Esposito, Angela, Bardelli, Alberto, Criscitiello, Carmen, Colombo, Nicoletta, Gelao, Lucia, Fumagalli, Luca, Minchella, Ida, Locatelli, Marzia, Goldhirsch, Aron, Curigliano, Giuseppe

“…Abstract Circulating cell-free DNA represents a non-invasive biomarker, as it can be isolated from human plasma, serum and other body fluids. Circulating tumor…”
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Effect of age on safety and efficacy of novel cancer drugs investigated in early-phase clinical trials by Nicolò, Eleonora, Gandini, Sara, Giugliano, Federica, Uliano, Jacopo, D’Ecclesiis, Oriana, Morganti, Stefania, Ferraro, Emanuela, Trapani, Dario, Tarantino, Paolo, Zagami, Paola, Boldrini, Laura, Caramella, Irene, Carnevale Schianca, Ambra, Cristofanilli, Massimo, Locatelli, Marzia Adelia, Esposito, Angela, Belli, Carmen, Minchella, Ida, Criscitiello, Carmen, Marra, Antonio, Curigliano, Giuseppe

“…Elderly patients are underrepresented in clinical trials, particularly in early-phase studies. Our study assessed the safety and efficacy of novel anti-cancer…”
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Immune-Related Adverse Event Likelihood Score Identifies "Pure" IRAEs Strongly Associated With Outcome in a Phase I-II Trial Population by Mazzarella, Luca, Giugliano, Federica, Nicolo, Eleonora, Esposito, Angela, Crimini, Edoardo, Tini, Giulia, Uliano, Jacopo, Corti, Chiara, D'Amico, Paolo, Aliaga, Pamela Trillo, Valenza, Carmine, Repetto, Matteo, Antonarelli, Gabriele, Ascione, Liliana, Vivanet, Grazia, Berton Giachetti, Pierpaolo, Minchella, Ida, Belli, Carmen, Locatelli, Marzia, Criscitiello, Carmen, Curigliano, Giuseppe

“…Immune-related adverse events (IRAE) pose a significant diagnostic and therapeutic challenge in patients treated with immune-oncology (IO) drugs. IRAEs have…”
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Baseline Tumor Size as Prognostic Index in Patients With Advanced Solid Tumors Receiving Experimental Targeted Agents by Nicolò, Eleonora, Tarantino, Paolo, D'Ecclesiis, Oriana, Antonarelli, Gabriele, Boscolo Bielo, Luca, Marra, Antonio, Gandini, Sara, Crimini, Edoardo, Giugliano, Federica, Zagami, Paola, Corti, Chiara, Trapani, Dario, Morganti, Stefania, Criscitiello, Carmen, Locatelli, Marzia, Belli, Carmen, Esposito, Angela, Minchella, Ida, Cristofanilli, Massimo, Tolaney, Sara M, Curigliano, Giuseppe

“…Baseline tumor size (BTS) has been associated with outcomes in patients with cancer treated with immunotherapy. However, the prognostic impact of BTS on…”
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High Ki-67 score is indicative of a greater benefit from adjuvant chemotherapy when added to endocrine therapy in Luminal B HER2 negative and node-positive breast cancer by Criscitiello, Carmen, Disalvatore, Davide, De Laurentiis, Michele, Gelao, Lucia, Fumagalli, Luca, Locatelli, Marzia, Bagnardi, Vincenzo, Rotmensz, Nicole, Esposito, Angela, Minchella, Ida, De Placido, Sabino, Santangelo, Michele, Viale, Giuseppe, Goldhirsch, Aron, Curigliano, Giuseppe

“…Abstract Background The indication of adjuvant chemotherapy for patients with highly proliferative estrogen receptor-positive breast cancer is controversial…”
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Baseline tumor size as prognostic index in patients with cancer receiving experimental targeted agents by Tarantino, Paolo, D'Ecclesiis, Oriana, Nicolò, Eleonora, Antonarelli, Gabriele, Boscolo Bielo, Luca, Marra, Antonio, Gandini, Sara, Crimini, Edoardo, Giugliano, Federica, Zagami, Paola, Corti, Chiara, Trapani, Dario, Morganti, Stefania, Criscitiello, Carmen, Locatelli, Marzia Adelia, Belli, Carmen, Esposito, Angela, Minchella, Ida, Tolaney, Sara M., Curigliano, Giuseppe

“…3063 Background: Several studies showed that high baseline tumor size (BTS) is associated with worse outcomes in cancer patients treated with immunotherapy…”
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Mechanisms of anorexia–cachexia syndrome and rational for treatment with selective ghrelin receptor agonist by Esposito, Angela, Criscitiello, Carmen, Gelao, Lucia, Pravettoni, Gabriella, Locatelli, Marzia, Minchella, Ida, Di Leo, Maria, Liuzzi, Rita, Milani, Alessandra, Massaro, Mariangela, Curigliano, Giuseppe

“…Highlights • Cancer cachexia is a multi-organ, multifactorial and often irreversible syndrome. • Treatment options for treating cancer cachexia are limited. •…”
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Safety of COVID-19 mRNA Vaccines in Patients with Cancer Enrolled in Early-Phase Clinical Trials by Trillo Aliaga, Pamela, Trapani, Dario, Sandoval, José Luis, Crimini, Edoardo, Antonarelli, Gabriele, Vivanet, Grazia, Morganti, Stefania, Corti, Chiara, Tarantino, Paolo, Friedlaender, Alex, Belli, Carmen, Minchella, Ida, Locatelli, Marzia, Esposito, Angela, Criscitiello, Carmen, Curigliano, Giuseppe

“…Pivotal trials of COVID-19 vaccines did not include cancer patients, with questions remaining about their safety and efficacy in this population. Patients…”
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Changes of HER2 Status in Circulating Tumor Cells Compared With the Primary Tumor During Treatment for Advanced Breast Cancer by Munzone, Elisabetta, Nolé, Franco, Goldhirsch, Aron, Botteri, Edoardo, Esposito, Angela, Zorzino, Laura, Curigliano, Giuseppe, Minchella, Ida, Adamoli, Laura, Cassatella, Maria Cristina, Casadio, Chiara, Sandri, Maria Teresa

“…Abstract Background HER2/ neu status of tumor cells at metastatic sites in patients with advanced disease may differ from that of the primary tumor. Assessing…”
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Dacarbazine in combination with bevacizumab for the treatment of unresectable/metastatic melanoma: a phase II study by Ferrucci, Pier F, Minchella, Ida, Mosconi, Massimo, Gandini, Sara, Verrecchia, Francesco, Cocorocchio, Emilia, Passoni, Claudia, Pari, Chiara, Testori, Alessandro, Coco, Paola, Munzone, Elisabetta

“…The combined treatment of dacarbazine with an antiangiogenic drug such as bevacizumab may potentiate the therapeutic effects of dacarbazine in metastatic…”
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QTc prolongation induced by targeted biotherapies used in clinical practice and under investigation: a comprehensive review by Locatelli, Marzia, Criscitiello, Carmen, Esposito, Angela, Minchella, Ida, Goldhirsch, Aron, Cipolla, Carlo, Curigliano, Giuseppe

“…In anticancer drug development, there has been increasing consideration for the potential of a compound to cause adverse electrocardiographic changes,…”
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Dendritic cell-based vaccines: clinical applications in breast cancer by Gelao, Lucia, Criscitiello, Carmen, Esposito, Angela, De Laurentiis, Michele, Fumagalli, Luca, Locatelli, Marzia Adelia, Minchella, Ida, Santangelo, Michele, De Placido, Sabino, Goldhirsch, Aron, Curigliano, Giuseppe

“…Recent evidence suggests that the immune system is involved in the carcinogenesis process and the antitumor immune responses impact the clinical outcome, thus…”
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Developing an effective breast cancer vaccine: Challenges to achieving sterile immunity versus resetting equilibrium by Curigliano, Giuseppe, Criscitiello, Carmen, Esposito, Angela, Fumagalli, Luca, Gelao, Lucia, Locatelli, Marzia, Minchella, Ida, Goldhirsch, Aron

“…Abstract Introduction Evading immune destruction is an emerging hallmark of cancer. Immunotherapy of cancer is categorized as either specific stimulation of…”
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