Search Results - "Mincheff, M."

P1380: DEGREE OF CELL PACKING OF CRYOPRESERVED AT ‐80ºC HEMATOPOIETIC STEM CELLS DOES NOT AFFECT THEIR VIABILITY AND HEMATOLOGIC RECOVERY OF TRANSPLANTED MYELOMA PATIENTS by Tonev, I., Simeonov, S., Milcheva, K., Venkov, K., Ganeva, P., Arnaudov, G., Mincheff, M.

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PB2175: TRYPAN BLUE AND FLOW CYTOMETRY CELL VIABILITY TESTING OF PACKED OR DILUTED CRYOPRESERVED AT ‐80ºC HEMATOPOIETIC STEM CELLS SHOW SIMILAR RESULTS by Tonev, I., Simeonov, S., Ilieva, M., Muhtarova, M., Vladimirova, R., Andreinski, N., Yancheva, T., Guenova, M., MIncheff, M.

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Changes in Donor Leukocytes during Blood Storage. Implications on Post- Transfusion Immunomodulation and Transfusion-Associated GVHD by Mincheff, M.

“…Freshly drawn peripheral blood granulocytes, monocytes and NK cells express Fas‐L following activation. Fully functional soluble Fas‐L (sFas‐L) is released and…”
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Immunosurveillance and immunoediting--can the immune response be made more "immunodemocratic"? by Mincheff, M

“…Increasing evidence has demonstrated that the immune system is able to mount responses against tumors and that these responses can be enhanced using a number…”
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Immune responses against PSMA after gene-based vaccination for immunotherapy - A: results from immunizations in animals by Mincheff, M, Zoubak, S, Makogonenko, Y

“…Two plasmid DNA vaccines, encoding either products that are retained in the cytosol and degraded in the proteasome (tVacs; hPSMAt), or secreted proteins…”
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PB2195: MOBILIZATION WITH CYTARABINE AND GRANULOCYTE COLONY STIMULATING FACTOR (G-CSF) GIVES BETTER YIELD THAN MOBILIZATION WITH G-CSF ALONE OR COMBINED WITH CYCLOPHOSPHAMIDE by Simeonov, S., Tonev, I., Denchev, V., Stoichov, M., Davidkova, Y., Aleksov, E., Zhivkov, T., Stoyanova, M., Donchev, M., Arnaudov, G., Mincheff, M.

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Biochemical Nature and Mapping of PSMA Epitopes Recognized by Human Antibodies Induced after Immunization with Gene-based Vaccines by TODOROVA, K, ZOUBAK, S, MINCHEFF, M, KYURKCHIEV, S

“…Background: A possible new target for immunotherapy is the prostate-specific membrane antigen (PSMA). The aim of the present study was to define potential PSMA…”
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In vivo transfection and/or cross-priming of dendritic cells following DNA and adenoviral immunizations for immunotherapy of cancer—changes in peripheral mononuclear subsets and intracellular IL-4 and IFN-γ lymphokine profile by Mincheff, M., Altankova, I., Zoubak, S., Tchakarov, St, Botev, Ch, Petrov, St, Krusteva, E., Kurteva, G., Kurtev, P., Dimitrov, V., Ilieva, M., Georgiev, G., Lissitchkov, T., Chernozemski, Iv, Meryman, H.T.

“…In order to provoke an immune response, a tumor vaccine should not only maximize antigen-specific signals, but should also provide the necessary…”
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Blood transfusion and immunomodulation: a possible mechanism by Mincheff, M S, Meryman, H T, Kapoor, V, Alsop, P, Wötzel, M

“…To induce an immunogenic response in vivo, an antigen-presenting (stimulator) cell must present both antigen-specific (class II MHC) and an accessory signal to…”
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Mechanisms of alloimmunization and immunosuppression by blood transfusions in an inbred rodent model by Mincheff, M S, Getsov, S I, Meryman, H T

“…During refrigerated storage leukocytes in donor blood progressively undergo apoptosis followed by secondary necrosis. Using an inbred rodent transfusion model,…”
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Blood transfusion, blood storage and immunomodulation by Mincheff, M S, Meryman, H T

“…Allogeneic blood transfusion is the most frequent allotransplantation procedure performed on a routine basis with no prior HLA-typing. Roughly 50% of the…”
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PB2195: MOBILIZATION WITH CYTARABINE AND GRANULOCYTE COLONY STIMULATING FACTOR (G‐CSF) GIVES BETTER YIELD THAN MOBILIZATION WITH G‐CSF ALONE OR COMBINED WITH CYCLOPHOSPHAMIDE by Simeonov, S., Tonev, I., Denchev, V., Stoichov, M., Davidkova, Y., Aleksov, E., Zhivkov, T., Stoyanova, M., Donchev, M., Arnaudov, G., Mincheff, M.

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Fas and Fas Ligand Expression on Human Peripheral Blood Leukocytes by Mincheff, Milcho, Loukinov, Dmitri, Zoubak, Serguei, Hammett, Michael, Meryman, Harold

“…Objectives: Study of Fas and Fas ligand (Fas-L) expression, as well as sFas-L release, by fresh human peripheral blood leukocytes. Methods: Flow cytometry,…”
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Costimulatory signals necessary for induction of T cell proliferation by Mincheff, M S, Meryman, H T

“…Two separate signals are required for induction of T cell proliferation. In an attempt to identify them we used polyclonal T cell activation with Con A, which…”
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PF779 VIABILITY OF HEMATOPOETIC STEM CELLS FOLLOWING STORAGE AT −80OC WITH 5% DIMETHYLSULFOXIDE AND HEMATOLOGIC RECOVERY IN TRANSPLANTED MYELOMA PATIENTS by Tonev, I., Simeonov, S., Mitkov, I., Ilieva, M., Petrov, Y., Ganeva, P., Arnaudov, G., Spassov, B., Mincheff, M.

“…Background: Dimethylsulfoxide (DMSO) is a major intracellular cryoprotectant, used for cryopreservation of stem cells. It is toxic to both cells and patients…”
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PB2365 CELL DOSE AND HEMATOLOGIC RECOVERY AFTER AUTOLOGOUS STEM CELL TRANSPLANTATION FOR MULTIPLE MYELOMA by Tonev, I., Simeonov, S., Mitkov, I., Ilieva, M., Petrov, Y., Ganeva, P., Arnaudov, G., Spassov, B., Mincheff, M.

“…Background: The relation between the dose of the infused hematopoietic stem cells and the time of hematologic recovery after autologous transplantation has…”
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Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: a phase I/II clinical trial by Mincheff, M, Tchakarov, S, Zoubak, S, Loukinov, D, Botev, C, Altankova, I, Georgiev, G, Petrov, S, Meryman, H T

“…Animal studies have indicated that the use of syngeneic dendritic cells that have been transfected ex vivo with DNA for tumor-specific antigen results in tumor…”
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Tularemia outbreak, Bulgaria, 1997-2005 by Kantardjiev, Todor, Ivanov, Ivan, Velinov, Tzvetan, Padeshki, Plamen, Popov, Boris, Nenova, Roumiana, Mincheff, Milcho

“…The 1997-2005 tularemia outbreak in Bulgaria affected 285 people. Ten strains were isolated from humans, a tick, a hare, and water. Amplified fragment length…”
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Induction of primary mixed leukocyte reactions with ultraviolet B or chemically modified stimulator cells by Mincheff, M S, Meryman, H T

“…Treatment of stimulator cells with 0.1% paraformaldehyde for 60 sec or ultraviolet-B (UV-B) irradiation (1000 J/m2) eliminates their ability to elicit T cell…”
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Gene-based vaccines for immunotherapy (IT) of prostate cancer following radical prostatectomy — A 5-year experience from a clinical trial by Tchakarov, St, Altankova, I, Dimitrov, R, Pomakov, Y, Zoubak, S, Botev, C, Mincheff, M

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