Search Results - "Minas, Jacqueline N"
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Considerations when quantitating protein abundance by immunoblot
Published in American Journal of Physiology: Cell Physiology (15-03-2015)“…The development of the immunoblot to detect and characterize a protein with an antisera, even in a crude mixture, was a breakthrough with wide-ranging and…”
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Chronic AT1 blockade improves glucose homeostasis in obese OLETF rats
Published in Journal of endocrinology (01-06-2018)“…Obesity is associated with the inappropriate activation of the renin-angiotensin system (RAS), which increases arterial pressure, impairs insulin secretion and…”
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Angiotensin Receptor Blockade Increases Pancreatic Insulin Secretion and Decreases Glucose Intolerance during Glucose Supplementation in a Model of Metabolic Syndrome
Published in Endocrinology (Philadelphia) (01-04-2012)“…Renin-angiotensin system blockade improves glucose intolerance and insulin resistance, which contribute to the development of metabolic syndrome. However, the…”
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Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats
Published in Clinical and experimental pharmacology & physiology (01-11-2015)“…Summary Angiotensin II (Ang II) and aldosterone contribute to hypertension, oxidative stress and cardiovascular damage, but the contributions of aldosterone…”
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High fat diet contributes to improper kidney AT1 activation and impaired sodium regulation through ENaC cleavage in a model of insulin resistance
Published in The FASEB journal (01-04-2013)“…Abstract only High fat diet (HFD) is known to accelerate diabetic nephropathy (DN) while blockade of the renin angiotensin system (RAS) improves the…”
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Adipose Angiotensinogen is Upregulated during Insulin Resistance in OLETF Rats
Published in The FASEB journal (01-04-2013)“…Abstract only Activation of the renin‐angiotensin system (RAS) has been shown to contribute to metabolic syndrome. Hyptertension is a key component of…”
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Enriched Cholesterol Diet Increases Expression of Renal Epithelial Na+ Channel Gamma Subunit in Rats
Published in The FASEB journal (01-04-2012)“…Abstract only The epithelial Na + channel (ENaC) is a trimeric transmembrane channel expressed in multiple secretory organs. ENaC is responsible for regulation…”
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Decreased Pancreatic Insulin Secretion is associated with increased AT1 Activation during Glucose Supplementation in a Model of Metabolic Syndrome
Published in The FASEB journal (01-04-2012)“…Abstract only Blockade of the renin‐angiotensin‐system improves glucose intolerance, insulin resistance and beta cell function. The contributions of…”
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Angiotensin and Mineralocorticoid Receptor Antagonism Combined Improves Urinary 8‐Isoprostane Excretion in Ang II‐Infused Rats
Published in The FASEB journal (01-04-2011)“…Aldosterone and angiotensin II (AII) promote cardiovascular damage via increased oxidative stress. Mineralocorticoid receptor (MR) antagonism offers…”
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