Search Results - "Minardi Nascimento, Juliana"

Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT by Dakic, Vanja, Minardi Nascimento, Juliana, Costa Sartore, Rafaela, Maciel, Renata de Moraes, de Araujo, Draulio B., Ribeiro, Sidarta, Martins-de-Souza, Daniel, Rehen, Stevens K.

“…Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional Amerindian medicine recently associated with cognitive gains,…”
Get full text

Zika virus impairs growth in human neurospheres and brain organoids by Garcez, Patricia P., Loiola, Erick Correia, da Costa, Rodrigo Madeiro, Higa, Luiza M., Trindade, Pablo, Delvecchio, Rodrigo, Nascimento, Juliana Minardi, Brindeiro, Rodrigo, Tanuri, Amilcar, Rehen, Stevens K.

“…Since the emergence of Zika virus (ZIKV), reports of microcephaly have increased considerably in Brazil; however, causality between the viral epidemic and…”
Get full text

DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-Derived Neurons by Fernandez Bessone, Iván, Navarro, Jordi, Martinez, Emanuel, Karmirian, Karina, Holubiec, Mariana, Alloatti, Matias, Goto-Silva, Livia, Arnaiz Yepez, Cayetana, Martins-de-Souza, Daniel, Minardi Nascimento, Juliana, Bruno, Luciana, Saez, Trinidad M, Rehen, Stevens K, Falzone, Tomás L

“…triplication in Down's syndrome and its overexpression in Alzheimer's disease suggest a role for increased DYRK1A activity in the abnormal metabolism of APP…”
Get full text

Cytotoxicity of Lachesis muta muta snake (bushmaster) venom and its purified basic phospholipase A2 (LmTX-I) in cultured cells by DAMICO, Daniela C. S, MINARDI NASCIMENTO, Juliana, LOMONTE, Bruno, PONCE-SOTO, Luis A, JOAZEIRO, Paulo P, CAMILLO NOVELLO, José, MARANGONI, Sérgio, COLLARES-BUZATO, Carla B

“…Human envenoming by Lachesis muta muta venom, although infrequent, is rather severe, being characterized by pronounced local tissue damage and systemic…”
Get full text

Cytoskeletal rearrangement and cell death induced by Bothrops alternatus snake venom in cultured Madin-Darby canine kidney cells by Nascimento, Juliana Minardi, Franchi, Jr, Gilberto Carlos, Nowill, Alexandre Eduardo, Collares-Buzato, Carla Beatriz, Hyslop, Stephen

“…Bothrops snake venoms cause renal damage, with renal failure being the main cause of death in humans bitten by these snakes. In this work, we investigated the…”
Get more information

Proteomic signatures of schizophrenia-sourced iPSC-derived neural cells and brain organoids are similar to patients' postmortem brains by Nascimento, Juliana Minardi, Saia-Cereda, Verônica M, Zuccoli, Giuliana S, Reis-de-Oliveira, Guilherme, Carregari, Victor Corasolla, Smith, Bradley J, Rehen, Stevens K, Martins-de-Souza, Daniel

“…Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity…”
Get full text

Human Cerebral Organoids and Fetal Brain Tissue Share Proteomic Similarities by Nascimento, Juliana Minardi, Saia-Cereda, Verônica M, Sartore, Rafaela C, da Costa, Rodrigo Madeiro, Schitine, Clarissa S, Freitas, Hercules Rezende, Murgu, Michael, de Melo Reis, Ricardo A, Rehen, Stevens K, Martins-de-Souza, Daniel

“…The limited access to functional human brain tissue has led to the development of stem cell-based alternative models. The differentiation of human pluripotent…”
Get full text

Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization by Trindade, Pablo, Nascimento, Juliana Minardi, Casas, Bárbara S., Monteverde, Tomás, Gasparotto, Juciano, Ribeiro, Camila Tiefensee, Devalle, Sylvie, Sauma, Daniela, Moreira, José Claudio Fonseca, Gelain, Daniel Pens, Porciuncula, Lisiane O., Palma, Verónica, Martins-de-Souza, Daniel, Rehen, Stevens K.

“…Molecular and functional abnormalities of astrocytes have been implicated in the etiology and pathogenesis of schizophrenia (SCZ). In this study, we examined…”
Get full text

Derivation of Functional Human Astrocytes from Cerebral Organoids by Dezonne, Rômulo Sperduto, Sartore, Rafaela Costa, Nascimento, Juliana Minardi, Saia-Cereda, Verônica M., Romão, Luciana Ferreira, Alves-Leon, Soniza Vieira, de Souza, Jorge Marcondes, Martins-de-Souza, Daniel, Rehen, Stevens Kastrup, Gomes, Flávia Carvalho Alcantara

“…Astrocytes play a critical role in the development and homeostasis of the central nervous system (CNS). Astrocyte dysfunction results in several neurological…”
Get full text

Zika virus disrupts molecular fingerprinting of human neurospheres by Garcez, Patricia P., Nascimento, Juliana Minardi, de Vasconcelos, Janaina Mota, Madeiro da Costa, Rodrigo, Delvecchio, Rodrigo, Trindade, Pablo, Loiola, Erick Correia, Higa, Luiza M., Cassoli, Juliana S., Vitória, Gabriela, Sequeira, Patricia C., Sochacki, Jaroslaw, Aguiar, Renato S., Fuzii, Hellen Thais, de Filippis, Ana M. Bispo, da Silva Gonçalves Vianez Júnior, João Lídio, Tanuri, Amilcar, Martins-de-Souza, Daniel, Rehen, Stevens K.

“…Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development…”
Get full text

Zika Virus Strains and Dengue Virus Induce Distinct Proteomic Changes in Neural Stem Cells and Neurospheres by Nascimento, Juliana Minardi, Gouvêa-Junqueira, Danielle, Zuccoli, Giuliana S., Pedrosa, Carolina da Silva Gouveia, Brandão-Teles, Caroline, Crunfli, Fernanda, Antunes, André S. L. M., Cassoli, Juliana S., Karmirian, Karina, Salerno, José Alexandre, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Proenca-Módena, Jose Luiz, Higa, Luiza M., Tanuri, Amilcar, Garcez, Patricia P., Rehen, Stevens K., Martins-de-Souza, Daniel

“…Brain abnormalities and congenital malformations have been linked to the circulating strain of Zika virus (ZIKV) in Brazil since 2016 during the microcephaly…”
Get full text

Combining Patient-Reprogrammed Neural Cells and Proteomics as a Model to Study Psychiatric Disorders by Zuccoli, Giuliana S, Martins-de-Souza, Daniel, Guest, Paul C, Rehen, Stevens K, Nascimento, Juliana Minardi

“…The mechanisms underlying the pathophysiology of psychiatric disorders are still poorly known. Most of the studies about these disorders have been conducted on…”
Get more information

Effect of MK-801 and Clozapine on the Proteome of Cultured Human Oligodendrocytes by Cassoli, Juliana S, Iwata, Keiko, Steiner, Johann, Guest, Paul C, Turck, Christoph W, Nascimento, Juliana M, Martins-de-Souza, Daniel

“…Separate lines of evidence have demonstrated the involvement of N-methyl-D-aspartate (NMDA) receptor and oligodendrocyte dysfunctions in schizophrenia. Here,…”
Get full text

Cytotoxicity of Lachesis muta muta snake (bushmaster) venom and its purified basic phospholipase A 2 (LmTX-I) in cultured cells by Damico, Daniela C.S., Nascimento, Juliana Minardi, Lomonte, Bruno, Ponce-Soto, Luis A., Joazeiro, Paulo P., Novello, José Camillo, Marangoni, Sérgio, Collares-Buzato, Carla B.

“…Human envenoming by Lachesis muta muta venom, although infrequent, is rather severe, being characterized by pronounced local tissue damage and systemic…”
Get full text