Search Results - "Minakuchi, Yoshiko"
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Efficient Delivery of Small Interfering RNA to Bone-Metastatic Tumors by Using Atelocollagen in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (23-08-2005)“…Silencing of gene expression by small interfering RNAs (siRNAs) is rapidly becoming a powerful tool for genetic analysis and represents a potential strategy…”
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Atelocollagen-Mediated Systemic DDS for Nucleic Acid Medicines
Published in Annals of the New York Academy of Sciences (01-10-2006)“…: The goal of our research is to provide a practical platform for drug delivery in oligonucleotide therapy. We report here the efficacy of an…”
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Potential of atelocollagen-mediated systemic antisense therapeutics for inflammatory disease
Published in Human gene therapy (01-03-2004)“…To study the possibility of using atelocollagen as an oligonucleotide (ODN) delivery carrier in vivo, the activity of formulated antisense ODN targeted against…”
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Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
Published in Nucleic acids research (01-01-2004)“…Silencing gene expression by siRNAs is rapidly becoming a powerful tool for the genetic analysis of mammalian cells. However, the rapid degradation of siRNA…”
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199. Efficient Inhibition of Bone Metastasis Via Systemic Delivery of siRNA Using Atelocollagen-Mediated Delivery System
Published in Molecular therapy (01-05-2005)“…RNA interference has been one of the most powerful tool for genetic analysis, and much research on the development of siRNA for therapeutic use has progressed…”
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830. Efficient Transfer of Synthetic Small Interfering RNAs through Atelocollagen-Mediated Delivery System
Published in Molecular therapy (01-05-2004)“…Since it was observed that RNA interference which is an autologous protecting and regulating mechanism of eukaryotes can be worked artificially by introducing…”
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