Search Results - "Minagawa, Asako"

Small Dense Low-Density Lipoproteins Cholesterol can Predict Incident Cardiovascular Disease in an Urban Japanese Cohort: The Suita Study by Arai, Hidenori, Kokubo, Yoshihiro, Watanabe, Makoto, Sawamura, Tatsuya, Ito, Yasuki, Minagawa, Asako, Okamura, Tomonori, Miyamato, Yoshihiro

“…Aim: Several lines of evidence indicate that small dense low-density lipoproteins (sd-LDL) are more atherogenic than large buoyant LDL; however, few…”
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Crystal Structure of the tRNA 3′ Processing Endoribonuclease tRNase Z from Thermotoga maritima by Ishii, Ryohei, Minagawa, Asako, Takaku, Hiroaki, Takagi, Masamichi, Nashimoto, Masayuki, Yokoyama, Shigeyuki

“…The maturation of the tRNA 3′ end is catalyzed by a tRNA 3′ processing endoribonuclease named tRNase Z (RNase Z or 3′-tRNase) in eukaryotes, Archaea, and some…”
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A Novel Endonucleolytic Mechanism to Generate the CCA 3′ Termini of tRNA Molecules in Thermotoga maritima by Minagawa, Asako, Takaku, Hiroaki, Takagi, Masamichi, Nashimoto, Masayuki

“…The tRNA 3′-terminal CCA sequence is essential for aminoacylation of the tRNAs and for translation on the ribosome. The tRNAs are transcribed as larger…”
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Unstructured RNA Is a Substrate for tRNase Z by Shibata, Hirotaka S, Minagawa, Asako, Takaku, Hiroaki, Takagi, Masamichi, Nashimoto, Masayuki

“…tRNase Z, which exists in almost all cells, is believed to be working primarily for tRNA 3‘ maturation. In Escherichia coli, however, the tRNase Z gene appears…”
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Small, Dense LDL-Cholesterol is More Predictive Than Traditional Lipoproteins of Angiographic CAD in Females by Laury, Torrance, BS, Joshi, Parag, MD, Sharma, Abhinav, MD, Vazquez, Gustavo, MD, Qian, Zhen, PhD, Ito, Yasuki, PhD, Minagawa, Asako, PhD, Flockhart, Nancy, BS, CCRC, Marvasty, Idean, MS, Harmon, Mary, PhD, Brown, Charles, MD, Miller, Joseph, MD, Rinehart, Sarah, MD, Voros, Szilard, MD

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A candidate prostate cancer susceptibility gene encodes tRNA 3′ processing endoribonuclease by Takaku, Hiroaki, Minagawa, Asako, Takagi, Masamichi, Nashimoto, Masayuki

“…tRNA 3′ processing endoribonuclease (3′ tRNase) is an enzyme responsible for the removal of a 3′ trailer from precursor tRNA (pre‐tRNA). We purified ∼85 kDa 3′…”
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The N-terminal half-domain of the long form of tRNase Z is required for the RNase 65 activity by Takaku, Hiroaki, Minagawa, Asako, Takagi, Masamichi, Nashimoto, Masayuki

“…Transfer RNA (tRNA) 3′ processing endoribonuclease (tRNase Z) is an enzyme responsible for the removal of a 3′ trailer from pre-tRNA. There exists two types of…”
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The Flexible Arm of tRNase Z Is Not Essential for Pre-tRNA Binding but Affects Cleavage Site Selection by Minagawa, Asako, Ishii, Ryohei, Takaku, Hiroaki, Yokoyama, Shigeyuki, Nashimoto, Masayuki

“…tRNase Z is an enzyme responsible for removing a 3′ trailer from pre-tRNA. Although most tRNase Zs cleave pre-tRNAs immediately after the discriminator…”
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Identification by Mn2+ rescue of two residues essential for the proton transfer of tRNase Z catalysis by Minagawa, Asako, Takaku, Hiroaki, Ishii, Ryohei, Takagi, Masamichi, Yokoyama, Shigeyuki, Nashimoto, Masayuki

“…Thermotoga maritima tRNase Z cleaves pre-tRNAs containing the 74CCA76 sequence precisely after the A76 residue to create the mature 3′ termini. Its crystal…”
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A novel 4-base-recognizing RNA cutter that can remove the single 3′ terminal nucleotides from RNA molecules by Takaku, Hiroaki, Minagawa, Asako, Takagi, Masamichi, Nashimoto, Masayuki

“…Mammalian tRNase ZL shows versatility in substrate recognition. This enzyme can not only process pre-tRNAs by cleaving off their 3′ trailer sequences, but also…”
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The missense mutations in the candidate prostate cancer gene ELAC2 do not alter enzymatic properties of its product by Minagawa, Asako, Takaku, Hiroaki, Takagi, Masamichi, Nashimoto, Masayuki

“…The candidate prostate cancer gene ELAC2 encodes tRNA 3′ processing endoribonuclease (tRNase ZL). We produced recombinant human tRNase ZL's, which contain one…”
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A Novel Endonucleolytic Mechanism to Generate the CCA 3′ Termini of tRNA Molecules in Thermotoga maritima by Asako Minagawa, Hiroaki Takaku, Masamichi Takagi, Masayuki Nashimoto

“…The tRNA 3′-terminal CCA sequence is essential for aminoacylation of the tRNAs and for translation on the ribosome. The tRNAs are transcribed as larger…”
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Crystal Structure of the tRNA 3′ Processing Endoribonuclease tRNase Z from Thermotoga maritima by Ryohei Ishii, Asako Minagawa, Hiroaki Takaku, Masamichi Takagi, Masayuki Nashimoto, Shigeyuki Yokoyama

“…The maturation of the tRNA 3′ end is catalyzed by a tRNA 3′ processing endoribonuclease named tRNase Z (RNase Z or 3′-tRNase) in eukaryotes, Archaea, and…”
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Substrate recognition ability differs among various prokaryotic tRNase Zs by Minagawa, Asako, Takaku, Hiroaki, Shibata, Hirotaka S., Ishii, Ryohei, Takagi, Masamichi, Yokoyama, Shigeyuki, Nashimoto, Masayuki

“…There exists a significant difference in pre-tRNA preference among prokaryotic tRNase Zs. This is an enigma, because pre-tRNAs should form the common L-shaped…”
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The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes by Ishii, Ryohei, Minagawa, Asako, Takaku, Hiroaki, Takagi, Masamichi, Nashimoto, Masayuki, Yokoyama, Shigeyuki

“…tRNA 3′‐processing endoribonuclease (tRNase Z) is one of the enzymes involved in the 3′‐end processing of precursor tRNAs and is a member of the…”
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