Search Results - "Min, Tian"

Structures and gating mechanism of human TRPM2 by Wang, Longfei, Fu, Tian-Min, Zhou, Yiming, Xia, Shiyu, Greka, Anna, Wu, Hao

“…Transient receptor potential (TRP) melastatin 2 (TRPM2) is a cation channel associated with numerous diseases. It has a C-terminal NUDT9 homology (NUDT9H)…”
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Nanotechnology for Cancer Therapy Based on Chemotherapy by Zhao, Chen-Yang, Cheng, Rui, Yang, Zhe, Tian, Zhong-Min

“…Chemotherapy has been widely applied in clinics. However, the therapeutic potential of chemotherapy against cancer is seriously dissatisfactory due to the…”
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ICE-CBF-COR Signaling Cascade and Its Regulation in Plants Responding to Cold Stress by Hwarari, Delight, Guan, Yuanlin, Ahmad, Baseer, Movahedi, Ali, Min, Tian, Hao, Zhaodong, Lu, Ye, Chen, Jinhui, Yang, Liming

“…Cold stress limits plant geographical distribution and influences plant growth, development, and yields. Plants as sessile organisms have evolved complex…”
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Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly by Wang, Longfei, Wu, Di, Robinson, Carol V., Wu, Hao, Fu, Tian-Min

“…Vesicular- or vacuolar-type adenosine triphosphatases (V-ATPases) are ATP-driven proton pumps comprised of a cytoplasmic V1 complex for ATP hydrolysis and a…”
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Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway by Lee, Yu-Ru, Chen, Ming, Lee, Jonathan D, Zhang, Jinfang, Lin, Shu-Yu, Fu, Tian-Min, Chen, Hao, Ishikawa, Tomoki, Chiang, Shang-Yin, Katon, Jesse, Zhang, Yang, Shulga, Yulia V, Bester, Assaf C, Fung, Jacqueline, Monteleone, Emanuele, Wan, Lixin, Shen, Chen, Hsu, Chih-Hung, Papa, Antonella, Clohessy, John G, Teruya-Feldstein, Julie, Jain, Suresh, Wu, Hao, Matesic, Lydia, Chen, Ruey-Hwa, Wei, Wenyi, Pandolfi, Pier Paolo

“…Activation of tumor suppressors for the treatment of human cancer has been a long sought, yet elusive, strategy. PTEN is a critical tumor suppressive…”
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Axial Compressive Mechanical Behaviors of a Double-Layer Member by Tian, Li-Min, Jin, Bei-Bei, Li, Lei

“…AbstractThe instability of structural members under axial compression most likely causes spatial structural collapse. Therefore, the configuration of…”
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Oligosaccharides in straw hydrolysate could improve the production of single‐cell protein with Saccharomyces cerevisiae by Yang, Fan, Jin, Zheng, Nawaz, Muhammad, Xiao, Ying, Jiang, Yipeng, Hu, Jiajun, Li, Jixiang, Gao, Min‐Tian

“…BACKGROUND Using agricultural wastes to produce single‐cell proteins (SCP) can reduce production costs effectively. The aims of this study were to investigate…”
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Comparison of achieved and predicted tooth movement of maxillary first molars and central incisors: First premolar extraction treatment with Invisalign by Dai, Fan-Fan, Xu, Tian-Min, Shu, Guang

“…To compare achieved and predicted tooth movements of maxillary first molars and central incisors in first premolar extraction cases treated with Invisalign…”
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Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1 by Li, Yang, Fu, Tian-Min, Lu, Alvin, Witt, Kristen, Ruan, Jianbin, Shen, Chen, Wu, Hao

“…Canonical inflammasomes are cytosolic supramolecular complexes that activate caspase-1 upon sensing extrinsic microbial invasions and intrinsic sterile stress…”
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Mechanism of TRPM2 channel gating revealed by cryo‐EM by Xia, Shiyu, Wang, Longfei, Fu, Tian‐Min, Wu, Hao

“…Transient receptor potential melastatin 2 (TRPM2) is a non‐selective cation channel that allows Ca2+ influx across the plasma membrane and efflux from…”
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Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense by Shen, Zhangfei, Lin, Qingpeng, Yang, Xiao-Yuan, Fosuah, Elizabeth, Fu, Tian-Min

“…SIR2-HerA, a bacterial two-protein anti-phage defense system, induces bacterial death by depleting NAD upon phage infection. Biochemical reconstitution of…”
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Comparison of achieved and predicted crown movement in adults after 4 first premolar extraction treatment with Invisalign by Dai, Fan-fan, Xu, Tian-min, Shu, Guang

“…In this study, we compared achieved and predicted crown movements of maxillary and mandibular first molars, canines, and central incisors in adults after 4…”
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Gasdermin D pore structure reveals preferential release of mature interleukin-1 by Xia, Shiyu, Zhang, Zhibin, Magupalli, Venkat Giri, Pablo, Juan Lorenzo, Dong, Ying, Vora, Setu M., Wang, Longfei, Fu, Tian-Min, Jacobson, Matthew P., Greka, Anna, Lieberman, Judy, Ruan, Jianbin, Wu, Hao

“…As organelles of the innate immune system, inflammasomes activate caspase-1 and other inflammatory caspases that cleave gasdermin D (GSDMD). Caspase-1 also…”
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Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling by Pan, Liqiang, Fu, Tian-Min, Zhao, Wenbin, Zhao, Linlin, Chen, Wen, Qiu, Chixiao, Liu, Wenhui, Liu, Zhijun, Piai, Alessandro, Fu, Qingshan, Chen, Shuqing, Wu, Hao, Chou, James J.

“…Receptor clustering on the cell membrane is critical in the signaling of many immunoreceptors, and this mechanism has previously been attributed to the…”
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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes by Robert Hollingsworth, L., David, Liron, Li, Yang, Griswold, Andrew R., Ruan, Jianbin, Sharif, Humayun, Fontana, Pietro, Orth-He, Elizabeth L., Fu, Tian-Min, Bachovchin, Daniel A., Wu, Hao

“…NLRP1 and CARD8 are related cytosolic sensors that upon activation form supramolecular signalling complexes known as canonical inflammasomes, resulting in…”
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Structural Biology of Innate Immunity by Yin, Qian, Fu, Tian-Min, Li, Jixi, Wu, Hao

“…Innate immune responses depend on timely recognition of pathogenic or danger signals by multiple cell surface or cytoplasmic receptors and transmission of…”
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Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold by Fontana, Pietro, Dong, Ying, Pi, Xiong, Tong, Alexander B, Hecksel, Corey W, Wang, Longfei, Fu, Tian-Min, Bustamante, Carlos, Wu, Hao

“…INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of…”
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K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair by Liu, Pengda, Gan, Wenjian, Su, Siyuan, Hauenstein, Arthur V, Fu, Tian-Min, Brasher, Bradley, Schwerdtfeger, Carsten, Liang, Anthony C, Xu, Ming, Wei, Wenyi

“…Polyubiquitylation is canonically viewed as a posttranslational modification that governs protein stability or protein-protein interactions, in which distinct…”
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Molecular mechanism for NLRP6 inflammasome assembly and activation by Shen, Chen, Lu, Alvin, Xie, Wen Jun, Ruan, Jianbin, Negro, Roberto, Egelman, Edward H., Fu, Tian-Min, Wu, Hao

“…Inflammasomes are large protein complexes that trigger host defense in cells by activating inflammatory caspases for cytokine maturation and pyroptosis. NLRP6…”
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HDAC11: a rising star in epigenetics by Liu, Shan-Shan, Wu, Fei, Jin, Yue-Mei, Chang, Wei- Qin, Xu, Tian-Min

“…[Display omitted] •HDAC11 is the latest member of histone deacetylase family.•HDAC11 is closely associated with tumor development and prognosis.•HDAC11 is…”
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