Search Results - "Min, Sunwoo"

Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks by Ha, Geun-Hyoung, Ji, Jae-Hoon, Chae, Sunyoung, Park, Jihyun, Kim, Suhyeon, Lee, Jin-Kwan, Kim, Yonghyeon, Min, Sunwoo, Park, Jeong-Min, Kang, Tae-Hong, Lee, Ho, Cho, Hyeseong, Lee, Chang-Woo

“…DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational…”
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Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms by Lee, Ho-Soo, Min, Sunwoo, Jung, Ye-Eun, Chae, Sunyoung, Heo, June, Lee, Jae-Ho, Kim, TaeSoo, Kang, Ho-Chul, Nakanish, Makoto, Cha, Sun-Shin, Cho, Hyeseong

“…The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to…”
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Chromatin-remodeling factor, RSF1, controls p53-mediated transcription in apoptosis upon DNA strand breaks by Min, Sunwoo, Kim, Keeeun, Kim, Seong-Gwang, Cho, Hyeseong, Lee, Youngsoo

“…Remodeling and spacing factor 1 (RSF1), which is one of chromatin-remodeling factors, has been linked to the DNA damage response (DDR) and DNA repair. However,…”
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CDK4/6 inhibitors induce breast cancer senescence with enhanced anti‐tumor immunogenic properties compared with DNA‐damaging agents by Lee, Dong Hyun, Imran, Muhammad, Choi, Jae Ho, Park, Yoo Jung, Kim, Young Hwa, Min, Sunwoo, Park, Tae Jun, Choi, Yong Won

“…Since therapy‐induced senescence (TIS) can either support or inhibit cancer progression, identifying which types of chemotherapeutic agents can produce the…”
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Spatial and clonality-resolved 3D cancer genome alterations reveal enhancer-hijacking as a potential prognostic marker for colorectal cancer by Kim, Kyukwang, Kim, Mooyoung, Lee, Andrew J., Song, Sang-Hyun, Kang, Jun-Kyu, Eom, Junghyun, Kang, Gyeong Hoon, Bae, Jeong Mo, Min, Sunwoo, Kim, Yeonsoo, Lim, Yoojoo, Kim, Han Sang, Kim, Young-Joon, Kim, Tae-You, Jung, Inkyung

“…The regulatory effect of non-coding large-scale structural variations (SVs) on proto-oncogene activation remains unclear. This study investigated SV-mediated…”
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Post-Translational Regulation of the RSF1 Chromatin Remodeler under DNA Damage by Min, Sunwoo, Choi, Yong Won, Yun, Hansol, Jo, Sujin, Ji, Jae-Hoon, Cho, Hyeseong

“…Chromatin remodeling factors are involved in many cellular processes such as transcription, replication, and DNA damage response by regulating chromatin…”
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RSF1 orchestrates p53 transcriptional activity by coordinating p300 acetyltransferase and FACT complex by Heo, Yungyeong, Kim, Yonghyeon, Lim, Won Chung, Cho, Hyeseong, Choi, Yong Won, Min, Sunwoo

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Transcriptional regulation and chromatin dynamics at DNA double-strand breaks by Min, Sunwoo, Ji, Jae-Hoon, Heo, Yungyeong, Cho, Hyeseong

“…In eukaryotic cells, DNA damage can occur at any time and at any chromatin locus, including loci at which active transcription is taking place. DNA…”
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Probabilistic establishment of speckle-associated inter-chromosomal interactions by Joo, Jaegeon, Cho, Sunghyun, Hong, Sukbum, Min, Sunwoo, Kim, Kyukwang, Kumar, Rajeev, Choi, Jeong-Mo, Shin, Yongdae, Jung, Inkyung

“…Abstract Inter-chromosomal interactions play a crucial role in genome organization, yet the organizational principles remain elusive. Here, we introduce a…”
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The chromatin remodeler RSF1 coordinates epigenetic marks for transcriptional repression and DSB repair by Min, Sunwoo, Lee, Ho-Soo, Ji, Jae-Hoon, Heo, Yungyeong, Kim, Yonghyeon, Chae, Sunyoung, Choi, Yong Won, Kang, Ho-Chul, Nakanishi, Makoto, Cho, Hyeseong

“…Abstract DNA lesions impact on local transcription and the damage-induced transcriptional repression facilitates efficient DNA repair. However, how chromatin…”
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PARP1-TRIM44-MRN loop dictates the response to PARP inhibitors by Kim, Yonghyeon, Min, Sunwoo, Kim, Soyeon, Lee, Seo Yun, Park, Yeon-Ji, Heo, Yungyeong, Park, Soon Sang, Park, Tae Jun, Lee, Jae-Ho, Kang, Ho Chul, Ji, Jae-Hoon, Cho, Hyeseong

“…PARP inhibitors (PARPi) show selective efficacy in tumors with homologous recombination repair (HRR)-defects but the activation mechanism of HRR pathway in…”
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Regulation of nuclear DNA damage response by mitochondrial morphofunctional pathway by Oanh, Nguyen Thi Kim, Lee, Ho-Soo, Kim, Yong-Hyun, Min, Sunwoo, Park, Yeon-Ji, Heo, June, Park, Yong-Yea, Lim, Won-Chung, Cho, Hyeseong

“…Abstract Cells are constantly challenged by genotoxic stresses that can lead to genome instability. The integrity of the nuclear genome is preserved by the DNA…”
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De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair by Ji, Jae-Hoon, Min, Sunwoo, Chae, Sunyoung, Ha, Geun-Hyoung, Kim, Yonghyeon, Park, Yeon-Ji, Lee, Chang-Woo, Cho, Hyeseong

“…Abstract Histone H2AX undergoes a phosphorylation switch from pTyr142 (H2AX-pY142) to pSer139 (γH2AX) in the DNA damage response (DDR); however, the functional…”
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Ruxolitinib Improves Immune-Dysregulation Features but not Epigenetic Abnormality in a Patient with STAT1 GOF by Koh, June-Young, Kim, Doo Ri, Son, Sohee, Park, Hwanhee, Kim, Kyung-Ran, Min, Sunwoo, Lee, Ha Seok, Jhun, Byung Woo, Kang, Eun-Suk, Jung, Inkyung, Kang, Ji-Man, Kim, Yae-Jean, Shin, Eui-Cheol

“…Purpose Patients with STAT1 gain-of-function (GOF) mutations often exhibit autoimmune features. The JAK1/2 inhibitor ruxolitinib can be administered to…”
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ATM-dependent chromatin remodeler Rsf-1 facilitates DNA damage checkpoints and homologous recombination repair by Min, Sunwoo, Jo, Sujin, Lee, Ho-Soo, Chae, Sunyoung, Lee, Jong-Soo, Ji, Jae-Hoon, Cho, Hyeseong

“…As a member of imitation switch (ISWI) family in ATP-dependent chromatin remodeling factors, RSF complex consists of SNF2h ATPase and Rsf-1. Although it has…”
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Post-Translational Regulation of the RSF1 Chromatin Remodeler under DNA Damage by Min, Sunwoo, Choi, Yong Won, Yun, Hansol, Jo, Sujin, Ji, Jae-Hoon, Cho, Hyeseong

“…Chromatin remodeling factors are involved in many cellular processes such as transcription, replication, and DNA damage response by regulating chromatin…”
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The neuroprotective effects of human growth hormone as a potential treatment for amyotrophic lateral sclerosis by Chung, Jin-Young, Sunwoo, Jun-Sang, Kim, Min-Wook, Kim, Manho

“…Human growth hormone（GH）is a single-chain polypeptide of 191 amino acids that is involved in the regulation of various physiological processes,such as growth…”
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Impact of Rsf1 deficiency on DNA damage response in the nervous system by Kim, Keeeun, Min, Sunwoo, Cho, Hyeseong, Lee, Youngsoo

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