Search Results - "Min, Kyung Hyun"

The M-CSF receptor in osteoclasts and beyond by Mun, Se Hwan, Park, Peter Sang Uk, Park-Min, Kyung-Hyun

“…Colony-stimulating factor 1 receptor (CSF1R, also known as c-FMS) is a receptor tyrosine kinase. Macrophage colony-stimulating factor (M-CSF) and IL-34 are…”
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Role of Lysine‐Specific Demethylase 1 in Metabolically Integrating Osteoclast Differentiation and Inflammatory Bone Resorption Through Hypoxia‐Inducible Factor 1α and E2F1 by Doi, Kohei, Murata, Koichi, Ito, Shuji, Suzuki, Akari, Terao, Chikashi, Ishie, Shinichiro, Umemoto, Akio, Murotani, Yoshiki, Nishitani, Kohei, Yoshitomi, Hiroyuki, Fujii, Takayuki, Watanabe, Ryu, Hashimoto, Motomu, Murakami, Kosaku, Tanaka, Masao, Ito, Hiromu, Park‐Min, Kyung‐Hyun, Ivashkiv, Lionel B., Morinobu, Akio, Matsuda, Shuichi

“…Objective Hypoxia occurs in tumors, infections, and sites of inflammation, such as in the affected joints of patients with rheumatoid arthritis (RA). It…”
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Precise stacking of decellularized extracellular matrix based 3D cell-laden constructs by a 3D cell printing system equipped with heating modules by Ahn, Geunseon, Min, Kyung-Hyun, Kim, Changhwan, Lee, Jeong-Seok, Kang, Donggu, Won, Joo-Yun, Cho, Dong-Woo, Kim, Jun-Young, Jin, Songwan, Yun, Won-Soo, Shim, Jin-Hyung

“…Three-dimensional (3D) cell printing systems allow the controlled and precise deposition of multiple cells in 3D constructs. Hydrogel materials have been used…”
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General Worker's Sleep Disturbances and the Degree of Cold-Heat Symptoms: a national cross-sectional survey by Hyun, Min Kyung

“…Few studies have examined the impact of healthy sleep among general workers on individuals and society. Therefore, the status and risk factors of sleep…”
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Sexual Dimorphism in Differentiating Osteoclast Precursors Demonstrates Enhanced Inflammatory Pathway Activation in Female Cells by Mun, Se Hwan, Jastrzebski, Sandra, Kalinowski, Judy, Zeng, Steven, Oh, Brian, Bae, Seyeon, Eugenia, Giannopoulou, Khan, Nazir M, Drissi, Hicham, Zhou, Ping, Shin, Bongjin, Lee, Sun‐Kyeong, Lorenzo, Joseph, Park‐Min, Kyung‐Hyun

“…ABSTRACT Sexual dimorphism of the skeleton is well documented. At maturity, the male skeleton is typically larger and has a higher bone density than the female…”
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General Worker's Sleep Disturbances and the Degree of Cold-Heat Symptoms: a national cross-sectional survey by Min Kyung Hyun

“…Objectives: Few studies have examined the impact of healthy sleep among general workers on individuals and society. Therefore, the status and risk factors of…”
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Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation by Park, Sung Ho, Kang, Kyuho, Giannopoulou, Eugenia, Qiao, Yu, Kang, Keunsoo, Kim, Geonho, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B

“…No response by an immune cell occurs in isolation but is instead the summation of multiple interacting signals. Ivashkiv and colleagues describe the epigenetic…”
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The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair by Kusnadi, Anthony, Park, Sung Ho, Yuan, Ruoxi, Pannellini, Tania, Giannopoulou, Eugenia, Oliver, David, Lu, Theresa, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.

“…Cytokine tumor necrosis factor (TNF)-mediated macrophage polarization is important for inflammatory disease pathogenesis, but the mechanisms regulating…”
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A potential dermal substitute using decellularized dermis extracellular matrix derived bio-ink by Won, Joo-Yun, Lee, Mi-Hee, Kim, Mi-Jeong, Min, Kyung-Hyun, Ahn, Geunseon, Han, Ji-Seok, Jin, Songwan, Yun, Won-Soo, Shim, Jin-Hyung

“…Upon bioprinting, cells are mixed with a biomaterial to fabricate a living tissue, thus emphasizing the importance of biomaterials. The biomaterial used in…”
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Regulation of Osteoclast Differentiation and Activity by Lipid Metabolism by Kim, Haemin, Oh, Brian, Park-Min, Kyung-Hyun

“…Bone is a dynamic tissue and is constantly being remodeled by bone cells. Metabolic reprogramming plays a critical role in the activation of these bone cells…”
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An Overview of Systematic Reviews: Complementary Therapies for Cancer Patients by Lee, Seong Min, Choi, Ho Cheol, Hyun, Min Kyung

“…Introduction: This article critically examines the systematic reviews (SR) and meta-analysis (MA) of complementary therapies for cancer patients to appraise…”
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IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation by Kang, Kyuho, Bachu, Mahesh, Park, Sung Ho, Kang, Keunsoo, Bae, Seyeon, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.

“…Activation of macrophage proinflammatory and antimicrobial phenotypes is regulated by IFN-γ and LPS via synergistic induction of canonical, inflammatory NF-κB…”
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TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes by Ivashkiv, Lionel B, Yarilina, Anna, Park-Min, Kyung-Hyun, Antoniv, Taras, Hu, Xiaoyu

“…Rapid induction of inflammatory genes by tumor necrosis factor (TNF) has been well studied, but little is known about delayed and chronic TNF responses. Here…”
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Indirect Inhibition of Toll-like Receptor and Type I Interferon Responses by ITAM-Coupled Receptors and Integrins by Wang, Lu, Gordon, Rachael A., Huynh, Linda, Su, Xiaodi, Min, Kyung-Hyun Park, Han, Jiahuai, Arthur, J. Simon, Kalliolias, George D., Ivashkiv, Lionel B.

“…An important function of immunoreceptor tyrosine-based activation motif (ITAM)-coupled receptors is cross-regulation of heterologous receptor signaling, but…”
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Tumor necrosis factor induces GSK3 kinase–mediated cross-tolerance to endotoxin in macrophages by Park, Sung Ho, Park-Min, Kyung-Hyun, Chen, Janice, Hu, Xiaoyu, Ivashkiv, Lionel B

“…Tumor necrosis factor promotes potent inflammatory immune responses that can result in pathological tissue damage. Ivashkiv and colleagues show that it induces…”
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Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis by Murata, Koichi, Fang, Celestia, Terao, Chikashi, Giannopoulou, Eugenia G., Lee, Ye Ji, Lee, Min Joon, Mun, Se-Hwan, Bae, Seyeon, Qiao, Yu, Yuan, Ruoxi, Furu, Moritoshi, Ito, Hiromu, Ohmura, Koichiro, Matsuda, Shuichi, Mimori, Tsuneyo, Matsuda, Fumihiko, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.

“…Hypoxia augments inflammatory responses and osteoclastogenesis by incompletely understood mechanisms. We identified COMMD1 as a cell-intrinsic negative…”
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Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8 by Fang, Celestia, Qiao, Yu, Mun, Se Hwan, Lee, Min Joon, Murata, Koichi, Bae, Seyeon, Zhao, Baohong, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B

“…Osteoclasts are resorptive cells that are important for homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important…”
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MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages by Bae, Seyeon, Park, Peter Sang Uk, Lee, Yeji, Mun, Se Hwan, Giannopoulou, Eugenia, Fujii, Takayuki, Lee, Kelvin P, Violante, Sara Nunes, Cross, Justin R, Park-Min, Kyung-Hyun

“…MYC activates different metabolic programs in a cell-type- and cell-status-dependent manner. However, the role of MYC in inflammatory macrophages has not yet…”
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Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression by Lee, Min Joon, Lim, Elisha, Mun, Se-Hwan, Bae, Seyeon, Murata, Koichi, Ivashkiv, Lionel B., Park-Min, Kyung-Hyun

“…Investigations on the therapeutic effects of intravenous immunoglobulin (IVIG) have focused on the suppression of autoantibody and immune complex‐mediated…”
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Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation by Park-Min, Kyung-Hyun, Lim, Elisha, Lee, Min Joon, Park, Sung Ho, Giannopoulou, Eugenia, Yarilina, Anna, van der Meulen, Marjolein, Zhao, Baohong, Smithers, Nicholas, Witherington, Jason, Lee, Kevin, Tak, Paul P., Prinjha, Rab K., Ivashkiv, Lionel B

“…Emerging evidence suggests that RANKL-induced changes in chromatin state are important for osteoclastogenesis, but these epigenetic mechanisms are not well…”
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