Search Results - "Miltner, Erich"
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1
Cell death sensitization of leukemia cells by opioid receptor activation
Published in Oncotarget (01-05-2013)“…Cyclic AMP (cAMP) regulates a number of cellular processes and modulates cell death induction. cAMP levels are altered upon stimulation of specific…”
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2
Improved STR typing of telogen hair root and hair shaft DNA
Published in Electrophoresis (01-08-2007)“…Today the STR typing of telogen hair and hair shafts is regarded as a challenge. The small DNA quantity in the hair is highly degraded. Another problem are PCR…”
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3
DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin
Published in Molecular biology of the cell (01-08-2008)“…Resistance toward cytotoxic drugs is one of the primary causes for therapeutic failure in cancer therapy. DNA repair mechanisms as well as deficient caspases…”
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4
Automation of DNA and miRNA co-extraction for miRNA-based identification of human body fluids and tissues
Published in Electrophoresis (01-10-2016)“…In the last years, microRNA (miRNA) analysis came into focus in the field of forensic genetics. Yet, no standardized and recommendable protocols for…”
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5
Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma
Published in Cell cycle (Georgetown, Tex.) (15-05-2014)“…Glioblastoma are the most frequent and malignant human brain tumors, having a very poor prognosis. The enhanced radio- and chemoresistance of glioblastoma and…”
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The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans
Published in World journal of surgery (2017)“…Background The incidence of cardiac injury in immediate fatalities after blunt trauma remains underestimated, and reliable diagnostic strategies are still…”
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7
Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance
Published in Cancer research (Chicago, Ill.) (01-08-2008)“…The therapeutic opioid drug methadone (d,l-methadone hydrochloride) is the most commonly used maintenance medication for outpatient treatment of opioid…”
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Anti-CD33-antibodies labelled with the alpha-emitter Bismuth-213 kill CD33-positive acute myeloid leukaemia cells specifically by activation of caspases and break radio- and chemoresistance by inhibition of the anti-apoptotic proteins X-linked inhibitor of apoptosis protein and B-cell lymphoma-extra large
Published in European journal of cancer (1990) (01-07-2013)“…Abstract Aim The emerging interest in radioimmunotherapies employing alpha-emitters for cancer treatment like high risk-leukaemia leads to the question of how…”
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9
Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells
Published in Oncotarget (01-02-2013)“…Radioimmunotherapy (RIT) is an emerging treatment option for non-Hodgkin lymphoma (NHL) producing higher overall response and complete remission rates compared…”
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10
Casework testing of the multiplex kits AmpFℓSTR® SEfiler Plus™ PCR amplification kit (AB), PowerPlex® S5 System (Promega) and AmpFℓSTR® MiniFiler™ PCR amplification kit (AB)
Published in Forensic science international : genetics (01-04-2010)“…Abstract The short tandem repeat (STR) kits SEfiler Plus™ (D3S1358, FGA, D8S1179, D18S51, D21S11, TH01, VWA, SE33, D2S1338, D16S539, D19S433 and Amelogenin),…”
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11
Validation of the Short Amplicon Multiplex Q8 Including the German DNA Database Systems
Published in Journal of forensic sciences (01-07-2009)“…: We have developed a concept to enable the analyzing of degraded stains with limited DNA template quantity. Therefore we have constructed a short tandem…”
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Q8—A short amplicon multiplex including the German DNA database systems
Published in Forensic science international : genetics (01-06-2007)“…Abstract We have developed a modified STR (short tandem repeat) concept including the eight German DNA database systems D3S1358, FGA, TH01, VWA, SE33, D8S1179,…”
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13
STR typing of hairs from domestic cats
Published in Forensic science international. Genetics supplement series (01-08-2008)“…Cats are popular domestic animals. Because of the constant hair loss, a lot of cat hairs are found in the household. These hairs could be used by a forensic…”
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Fatal poisoning with the antidepressive agent opipramol
Published in Forensic science international (12-01-1996)“…An ingestion of an unknown quantity (⩽3000 mg) of opipramol dihydrochloride in a suicide case is described. Quantitation of opipramol and its deshydroxyethyl…”
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Dissection of the anterior and middle cerebral artery with fatal ischemia following kicks to the head
Published in Forensic science international (01-01-1991)“…A 19-year-old male received kicks to his head in the course of a fight with other young people. On admission to hospital he became drowsy and developed a…”
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