Search Results - "Miltenberger, R J"
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The role of the agouti gene in the yellow obese syndrome
Published in The Journal of nutrition (01-09-1997)“…The yellow obese syndrome in mice encompasses many pleiotropic effects including yellow fur, maturity-onset obesity, hyperinsulinemia, insulin resistance,…”
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Combined effects of insulin treatment and adipose tissue-specific agouti expression on the development of obesity
Published in Proceedings of the National Academy of Sciences - PNAS (04-02-1997)“…The agouti gene product is a secreted protein that acts in a paracrine manner to regulate coat color in mammals. Several dominant mutations at the agouti locus…”
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Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements
Published in Genes & development (01-11-1990)“…The pattern of structures on most of the adult cuticle of Drosophila is determined in the larval imaginal disks. The Drosophila growth factor homolog…”
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An Agouti Mutation Lacking the Basic Domain Induces Yellow Pigmentation but Not Obesity in Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (20-07-1999)“…Chronic antagonism of melanocortin receptors by the paracrine-acting agouti gene product induces both yellow fur and a maturity-onset obesity syndrome in mice…”
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An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes
Published in The Journal of biological chemistry (25-07-1993)“…The proto-oncogene Raf-1 is a cytoplasmic serine/threonine kinase implicated in the signaling process in cell proliferation. To determine if Raf-1 is…”
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An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants
Published in Molecular and Cellular Biology (01-05-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of the agouti gene in obesity
Published in Journal of endocrinology (01-11-1997)Get full text
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Molecular and Phenotypic Analysis of 25 Recessive, Homozygous-Viable Alleles at the Mouse agouti Locus
Published in Genetics (Austin) (01-02-2002)“…Agouti is a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical band of yellow on otherwise black hairs of the…”
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v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1
Published in Cell growth & differentiation (01-05-1995)“…The serine/threonine kinase, Raf-1, is a component of intracellular signaling pathways that control responses to extracellular stimuli. Previously, we have…”
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An E-box-mediated increase in cad transcription at the G sub(1)/S-phase boundary is suppressed by inhibitory c-Myc mutants
Published in Molecular and cellular biology (01-01-1995)“…To better understand the signaling pathways which lead to DNA synthesis in mammalian cells, we have studied the transcriptional activation of genes needed…”
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