Search Results - "Milstead, Mark W."
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The formation of a covalent complex between a dipeptide ligand and the src SH2 domain
Published in Bioorganic & medicinal chemistry letters (19-05-1998)“…The X-ray crystal structure of the src SH2 domain revealed the presence of a thiol residue (Cys 188) located proximal to the phosphotyrosine portion of a…”
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Journal Article -
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Novel A-ring modified camptothecins as topoisomerase I inhibitors
Published in Bioorganic & medicinal chemistry letters (21-09-1995)“…A camptothecin derivative has been prepared wherein the A-ring is fused to an oxazole ring. The compound was prepared via a Friedlander condensation involving…”
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Journal Article