Search Results - "Miloushev, Vesselin"

Series of first-order phase shifts correct lattice reduction of fractional K-space indices by Miloushev, Vesselin Z., Deh, Kofi, Keshari, Kayvan R.

“…[Display omitted] •Multiplicative correction for lattice reduction of fractional K-space indices.•Inverse corrections in uniform and non-uniform sparse cases…”
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Comparative 13-year meta-analysis of the sensitivity and positive predictive value of ultrasound, CT, and MRI for detecting hepatocellular carcinoma by Hanna, Robert F., Miloushev, Vesselin Z., Tang, An, Finklestone, Lee A., Brejt, Sidney Z., Sandhu, Ranjit S., Santillan, Cynthia S., Wolfson, Tanya, Gamst, Anthony, Sirlin, Claude B.

“…Purpose To compare the per-lesion sensitivity and positive predictive value (PPV) of ultrasonography (US), computed tomography (CT), and magnetic resonance…”
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Free super-resolution MRI by BRICKD slices by Miloushev, Vesselin Z., Deh, Kofi, Keshari, Kayvan R.

“…[Display omitted] •Super-resolution in MRI by sub-pixel shifts of successive slices without slice overlap using a compressed sensing reconstruction.•Simple…”
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In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors by Salamanca-Cardona, Lucia, Shah, Hardik, Poot, Alex J., Correa, Fabian M., Di Gialleonardo, Valentina, Lui, Hui, Miloushev, Vesselin Z., Granlund, Kristin L., Tee, Sui S., Cross, Justin R., Thompson, Craig B., Keshari, Kayvan R.

“…The oncometabolite 2-hydroxyglutarate (2-HG) is a signature biomarker in various cancers, where it accumulates as a result of mutations in isocitrate…”
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A non-synthetic approach to extending the lifetime of hyperpolarized molecules using D2O solvation by Cho, Andrew, Eskandari, Roozbeh, Miloushev, Vesselin Z., Keshari, Kayvan R.

“…[Display omitted] •Solvation of molecules with amide-like groups in D2O extends amide-carbon T1 &T2.•This is due to a decrease in dipolar relaxation via proton…”
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Improved total sensitivity estimation for multiple receive coils in MRI using ratios of first-order statistics by Miloushev, Vesselin Z., Boltyanskiy, Rostislav, Granlund, Kristin L., Keshari, Kayvan R.

“…Object Spatial variation in the sensitivity profiles of receive coils in MRI leads to spatially dependent scaling of the signal amplitude across an image. In…”
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Imaging brain glucose metabolism in vivo reveals propionate as a major anaplerotic substrate in pyruvate dehydrogenase deficiency by Marin-Valencia, Isaac, Kocabas, Arif, Rodriguez-Navas, Carlos, Miloushev, Vesselin Z, González-Rodríguez, Manuel, Lees, Hannah, Henry, Kelly E, Vaynshteyn, Jake, Longo, Valerie, Deh, Kofi, Eskandari, Roozbeh, Mamakhanyan, Arsen, Berishaj, Marjan, Keshari, Kayvan R

“…A vexing problem in mitochondrial medicine is our limited capacity to evaluate the extent of brain disease in vivo. This limitation has hindered our…”
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Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models by Dong, Yiyu, Eskandari, Roozbeh, Ray, Chelsea, Granlund, Kristin L, Santos-Cunha, Lidia Dos, Miloushev, Vesselin Z, Tee, Sui Seng, Jeong, Sangmoo, Aras, Omer, Chen, Ying-Bei, Cheng, Emily H, Hsieh, James J, Keshari, Kayvan R

“…The ever-changing tumor microenvironment constantly challenges individual cancer cells to balance supply and demand, presenting tumor vulnerabilities and…”
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Optimized coherence selection by Miloushev, Vesselin Z., Palmer, Arthur G.

“…[Display omitted] •Formal procedure for determining cogwheel phase cycles.•Proof that cogwheel phase cycles are optimal under many conditions in NMR.•Results…”
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Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models by Kossatz, Susanne, Carney, Brandon, Schweitzer, Melanie, Carlucci, Giuseppe, Miloushev, Vesselin Z, Maachani, Uday B, Rajappa, Prajwal, Keshari, Kayvan R, Pisapia, David, Weber, Wolfgang A, Souweidane, Mark M, Reiner, Thomas

“…Diffuse intrinsic pontine glioma (DIPG) is a childhood brainstem tumor with a universally poor prognosis. Here, we characterize a positron emission tomography…”
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Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma by Di Gialleonardo, Valentina, Aldeborgh, Hannah N, Miloushev, Vesselin, Folkers, Kelly M, Granlund, Kristin, Tap, William D, Lewis, Jason S, Weber, Wolfgang A, Keshari, Kayvan R

“…Biomarkers predicting rapalog responses in sarcomas where PI3K and mTOR are often hyperactivated could improve the suitable recruitment of responsive patients…”
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Hyperpolarization MRI: Preclinical Models and Potential Applications in Neuroradiology by Miloushev, Vesselin Z, Keshari, Kayvan R, Holodny, Andrei I

“…ABSTRACTHyperpolarization is a novel technology that can dramatically increase signal to noise in magnetic resonance. The method is being applied to small…”
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Hyperpolarized 13C pyruvate mouse brain metabolism with absorptive-mode EPSI at 1T by Miloushev, Vesselin Z., Di Gialleonardo, Valentina, Salamanca-Cardona, Lucia, Correa, Fabian, Granlund, Kristin L., Keshari, Kayvan R.

“…[Display omitted] •Explicit modeling of signal in echo-planar spectroscopic imaging sequences.•Absorptive-mode EPSI by appropriate choice of initial spectral…”
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High-Throughput Indirect Quantitation of 13C Enriched Metabolites Using 1H NMR by Di Gialleonardo, Valentina, Tee, Sui Seng, Aldeborgh, Hannah N, Miloushev, Vesselin Z, Cunha, Lidia S, Sukenick, George D, Keshari, Kayvan R

“…Nuclear magnetic resonance (NMR) spectroscopy is widely used in metabolomics to perform quantitative profiling of low-molecular weight compounds from…”
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High-Throughput Indirect Quantitation of 13 C Enriched Metabolites Using 1 H NMR by Di Gialleonardo, Valentina, Tee, Sui Seng, Aldeborgh, Hannah N, Miloushev, Vesselin Z, Cunha, Lidia S, Sukenick, George D, Keshari, Kayvan R

“…Nuclear magnetic resonance (NMR) spectroscopy is widely used in metabolomics to perform quantitative profiling of low-molecular weight compounds from…”
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Metabolic Imaging of the Human Brain with Hyperpolarized 13C Pyruvate Demonstrates 13C Lactate Production in Brain Tumor Patients by Miloushev, Vesselin Z., Granlund, Kristin L., Boltyanskiy, Rostislav, Lyashchenko, Serge K., DeAngelis, Lisa M., Mellinghoff, Ingo K., Brennan, Cameron W., Tabar, Vivian, Yang, T. Jonathan, Holodny, Andrei I., Sosa, Ramon E., Guo, YanWei W., Chen, Albert P., Tropp, James, Robb, Fraser, Keshari, Kayvan R.

“…Hyperpolarized (HP) MRI using [1-13C] pyruvate is a novel method that can characterize energy metabolism in the human brain and brain tumors. Here, we present…”
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Dynamic Properties of a Type II Cadherin Adhesive Domain: Implications for the Mechanism of Strand-Swapping of Classical Cadherins by Miloushev, Vesselin Z., Bahna, Fabiana, Ciatto, Carlo, Ahlsen, Goran, Honig, Barry, Shapiro, Lawrence, Palmer, Arthur G.

“…Cadherin-mediated cell adhesion is achieved through dimerization of cadherin N-terminal extracellular (EC1) domains presented from apposed cells. The dimer…”
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A Case of Immunogammaglobulin 4–Related Disease by Miloushev, Vesselin Z, Cabrera, Manuel R, Ichise, Masanori

“…ABSTRACTAn 81-year-old woman with history of thyroiditis and a putative diagnosis of retroperitoneal fibrosis presented with abdominal pain, progressive…”
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Solution Structure of the NaV1.2 C-terminal EF-hand Domain by Miloushev, Vesselin Z., Levine, Joshua A., Arbing, Mark A., Hunt, John F., Pitt, Geoffrey S., Palmer, Arthur G.

“…Voltage-gated sodium channels initiate the rapid upstroke of action potentials in many excitable tissues. Mutations within intracellular C-terminal sequences…”
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Nephrogenic Systemic Fibrosis Risk and Liver Disease by Hanna, Robert F., Finkelstone, Lee A., Chow, Daniel S., Miloushev, Vesselin Z., Escudero, Mark R., Lagana, Stephen M., Prince, Martin R.

“…Objective. Evaluate the incidence of nephrogenic systemic fibrosis (NSF) in patients with liver disease in the peritransplant period. Materials and Methods…”
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