Search Results - "Milot, Guy"

alpha.-Alkylation and stereochemistry of cis- and trans-decahydroquinolines mediated by the formamidine and Boc activating groups. Synthesis of pumiliotoxin C by Meyers, A. I, Milot, Guy

Get full text

Pyridoxine hydroxamic acids as novel HIV-integrase inhibitors by Stranix, Brent R., Wu, Jinzi J., Milot, Guy, Beaulieu, Françis, Bouchard, Jean-Emanuel, Gouveia, Kristine, Forte, André, Garde, Seema, Wang, Zhigang, Mouscadet, Jean-François, Delelis, Olivier, Xiao, Yong

“…A series of pyridoxine hydroxamic acid derivatives were prepared and evaluated as inhibitors of HIV integrase complex and wild type virus. [Display omitted] A…”
Get full text

Regioselectivity in forming dipole-stabilized anions. Sites of metalation of indolines, tetrahydroquinolines, and benzazepines activated by N-formimidoyl or N-Boc groups by Meyers, A. I, Milot, Guy

Get full text

Structure-Based Design of Potent, Amidine-Derived Inhibitors of Factor Xa:  Evaluation of Selectivity, Anticoagulant Activity, and Antithrombotic Activity by Wiley, Michael R, Weir, Leonard C, Briggs, Steven, Bryan, Nancy A, Buben, John, Campbell, Charles, Chirgadze, Nickolay Y, Conrad, Richard C, Craft, Trelia J, Ficorilli, James V, Franciskovich, Jeffry B, Froelich, Larry L, Gifford-Moore, Donetta S, Goodson, Theodore, Herron, David K, Klimkowski, Valentine J, Kurz, Kenneth D, Kyle, Jeffery A, Masters, John J, Ratz, Andrew M, Milot, Guy, Shuman, Robert T, Smith, Tommy, Smith, Gerald F, Tebbe, Ann Louise, Tinsley, Jennifer M, Towner, Richard D, Wilson, Alexander, Yee, Ying K

“…To enhance the potency of 1,2-dibenzamidobenzene-derived inhibitors of factor Xa (fXa), an amidine substituent was incorporated on one of the benzoyl side…”
Get full text

The design and synthesis of substituted biphenyl libraries by Pavia, Michael R., Cohen, Michael P., Dilley, Garrett J., Dubuc, Gloria R., Durgin, Tracy L., Forman, Frank W., Hediger, Mark E., Milot, Guy, Powers, Timothy S., Sucholeiki, Irving, Zhou, Shulan, Hangauer, David G.

“…A novel scaffold system for the generation of diversity libraries has been designed which allows for rapid modification not only of functional groups, but…”
Get full text

Rearrangements and stereochemistry of S2 additions to olefins by STELIOU, K, GAREAU, Y, MILOT, G, SALAMA, P

Get full text

1,2-Dibenzamidobenzene Inhibitors of Human Factor Xa by Herron, David K, Goodson, Theodore, Wiley, Michael R, Weir, Leonard C, Kyle, Jeffrey A, Yee, Ying K, Tebbe, Ann Louise, Tinsley, Jennifer M, Mendel, David, Masters, John J, Franciskovich, Jeffry B, Sawyer, J. Scott, Beight, Douglas W, Ratz, Andrew M, Milot, Guy, Hall, Steven E, Klimkowski, Valentine J, Wikel, James H, Eastwood, Brian J, Towner, Richard D, Gifford-Moore, Donetta S, Craft, Trelia J, Smith, Gerald F

“…High-throughput screening of a combinatorial library of diamidophenols yielded lead compounds with the ability to inhibit human factor Xa (fXa) at micromolar…”
Get full text

A reinvestigation of the reported synthesis of the spirobenzyl isoquinoline alkaloid, iso-ochotensine by Meyers, A.I, Akahane, Atsushi, Struzka, Vladimir, Warmus, Joseph S, Gonzalez, Michael, Milot, Guy

“…Attempts to repeat the spirocyclization of isoquinoline carboxylic acids, 4, 5, 8, and 9 to the spiroketones, 6 led only to the formation of the…”
Get full text

Rearrangements and stereochemistry of sulfur additions to olefins by Steliou, Kosta, Gareau, Yves, Milot, Guy, Salama, Paul

Get full text

Synthesis of chiral 2,6-dithiabicyclo[3.1.1]heptane. The dithia parent analog of the TXA2 nucleus by Steliou, Kosta, Milot, Guy

Get full text