Search Results - "Milo, Tomer"

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  1. 1

    A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks by Karin, Omer, Raz, Moriya, Tendler, Avichai, Bar, Alon, Korem Kohanim, Yael, Milo, Tomer, Alon, Uri

    Published in Molecular systems biology (01-07-2020)
    “…Stress activates a complex network of hormones known as the hypothalamic–pituitary–adrenal (HPA) axis. The HPA axis is dysregulated in chronic stress and…”
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    Journal Article
  2. 2

    The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts by Mayer, Shimrit, Milo, Tomer, Isaacson, Achinoam, Halperin, Coral, Miyara, Shoval, Stein, Yaniv, Lior, Chen, Pevsner-Fischer, Meirav, Tzahor, Eldad, Mayo, Avi, Alon, Uri, Scherz-Shouval, Ruth

    Published in Nature communications (19-09-2023)
    “…The tumor microenvironment (TME) is comprised of non-malignant cells that interact with each other and with cancer cells, critically impacting cancer biology…”
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  3. 3

    Hormone seasonality in medical records suggests circannual endocrine circuits by Tendler, Avichai, Bar, Alon, Mendelsohn-Cohen, Netta, Karin, Omer, Kohanim, Yael Korem, Maimon, Lior, Milo, Tomer, Raz, Moriya, Mayo, Avi, Tanay, Amos, Alon, Uri

    “…Hormones control the major biological functions of stress response, growth, metabolism, and reproduction. In animals, these hormones show pronounced…”
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    Journal Article
  4. 4

    Major depressive disorder and bistability in an HPA-CNS toggle switch by Ron Mizrachi, Ben, Tendler, Avichai, Karin, Omer, Milo, Tomer, Haran, Dafna, Mayo, Avi, Alon, Uri

    Published in PLoS computational biology (01-12-2023)
    “…Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex and heterogeneous etiology. Most treatments take weeks to show…”
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  5. 5

    Dynamics of thyroid diseases and thyroid‐axis gland masses by Korem Kohanim, Yael, Milo, Tomer, Raz, Moriya, Karin, Omer, Bar, Alon, Mayo, Avi, Mendelson Cohen, Netta, Toledano, Yoel, Alon, Uri

    Published in Molecular systems biology (01-08-2022)
    “…Thyroid disorders are common and often require lifelong hormone replacement. Treating thyroid disorders involves a fascinating and troublesome delay, in which…”
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    Journal Article
  6. 6

    Excitable dynamics of flares and relapses in autoimmune diseases by Lebel, Yael, Milo, Tomer, Bar, Alon, Mayo, Avi, Alon, Uri

    Published in iScience (17-11-2023)
    “…Many autoimmune disorders exhibit flares in which symptoms erupt and then decline, as exemplified by multiple sclerosis (MS) in its relapsing-remitting form…”
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  7. 7

    Endocrine gland size is proportional to its target tissue size by Raz, Moriya, Milo, Tomer, Glass, David S., Mayo, Avi, Alon, Uri

    Published in iScience (20-09-2024)
    “…Endocrine glands secrete hormones into the circulation to target distant tissues and regulate their functions. The qualitative relationship between…”
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  8. 8

    Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamics by Milo, Tomer, Maimon, Lior, Cohen, Ben, Haran, Dafna, Segman, Dror, Danon, Tamar, Bren, Anat, Mayo, Avi, Cohen Rappaport, Gadi, McInnis, Melvin, Alon, Uri

    Published in iScience (15-03-2024)
    “…Bipolar disorder (BD) is marked by fluctuating mood states over months to years, often with elevated cortisol levels. Elevated cortisol can also trigger mood…”
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  9. 9

    Timescales of Human Hair Cortisol Dynamics by Maimon, Lior, Milo, Tomer, Moyal, Rina S., Mayo, Avi, Danon, Tamar, Bren, Anat, Alon, Uri

    Published in iScience (25-09-2020)
    “…Cortisol is a major human stress hormone, secreted within minutes of acute stress. Cortisol also has slower patterns of variation: a strong circadian rhythm…”
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  10. 10

    Autoimmune thyroid diseases as a cost of physiological autoimmune surveillance by Milo, Tomer, Korem Kohanim, Yael, Toledano, Yoel, Alon, Uri

    Published in Trends in immunology (01-05-2023)
    “…Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) are common human thyroid autoimmune diseases with opposite clinical manifestations.GD and HT originate…”
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  11. 11
  12. 12

    On the Many Faces of Easily Covered Polytopes by Florentin, Dan I, Milo, Tomer

    Published 23-10-2024
    “…Assume that $rB_{2}^{n} \subset P$ for some polytope $P \subset \mathbb{R}^n$, where $r \in (\frac{1}{2},1]$. Denote by $\mathcal{F}$ the set of facets of $P$,…”
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  13. 13

    Robust CATE Estimation Using Novel Ensemble Methods by Machluf, Oshri, Frostig, Tzviel, Shoham, Gal, Milo, Tomer, Berkman, Elad, Pryluk, Raviv

    Published 04-07-2024
    “…The estimation of Conditional Average Treatment Effects (CATE) is crucial for understanding the heterogeneity of treatment effects in clinical trials. We…”
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