Search Results - "Milo, Blerta"

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types by Lin, Yuan-Ta, Seo, Jinsoo, Gao, Fan, Feldman, Heather M., Wen, Hsin-Lan, Penney, Jay, Cam, Hugh P., Gjoneska, Elizabeta, Raja, Waseem K., Cheng, Jemmie, Rueda, Richard, Kritskiy, Oleg, Abdurrob, Fatema, Peng, Zhuyu, Milo, Blerta, Yu, Chung Jong, Elmsaouri, Sara, Dey, Dilip, Ko, Tak, Yankner, Bruce A., Tsai, Li-Huei

“…The apolipoprotein E4 (APOE4) variant is the single greatest genetic risk factor for sporadic Alzheimer’s disease (sAD). However, the cell-type-specific…”
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Disrupting the blood–brain barrier by focused ultrasound induces sterile inflammation by Kovacs, Zsofia I., Kim, Saejeong, Jikaria, Neekita, Qureshi, Farhan, Milo, Blerta, Lewis, Bobbi K., Bresler, Michele, Burks, Scott R., Frank, Joseph A.

“…MRI-guided pulsed focused ultrasound (pFUS) combined with systemic infusion of ultrasound contrast agent microbubbles (MB) causes localized blood–brain barrier…”
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iPSC‐derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss by Penney, Jay, Ralvenius, William T., Loon, Anjanet, Cerit, Oyku, Dileep, Vishnu, Milo, Blerta, Pao, Ping‐Chieh, Woolf, Hannah, Tsai, Li‐Huei

“…Genetic findings have highlighted key roles for microglia in the pathology of neurodegenerative conditions such as Alzheimer's disease (AD). A number of…”
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PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4 by Narayan, Priyanka, Sienski, Grzegorz, Bonner, Julia M., Lin, Yuan-Ta, Seo, Jinsoo, Baru, Valeriya, Haque, Aftabul, Milo, Blerta, Akay, Leyla A., Graziosi, Agnese, Freyzon, Yelena, Landgraf, Dirk, Hesse, William R., Valastyan, Julie, Barrasa, M. Inmaculada, Tsai, Li-Huei, Lindquist, Susan

“…The ε4 allele of apolipoprotein E (APOE4) is a genetic risk factor for many diseases, including late-onset Alzheimer’s disease (AD). We investigate the…”
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Physicochemical Characterization of Ferumoxytol, Heparin and Protamine Nanocomplexes for improved magnetic labeling of stem cells by Bryant, L. Henry, Kim, Saejeong J, Hobson, Matthew, Milo, Blerta, Kovacs, Zsofia I, Jikiria, Neekita, Lewis, Bobbi K, Aronova, Maria A, Sousa, Alioscka A, Zhang, Guofeng, Leapman, Richard D, Frank, Joseph A

“…Abstract Stem cell-based therapies have become a major focus in regenerative medicine and to treat diseases. A straightforward approach combining three drugs,…”
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APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia by Sienski, Grzegorz, Narayan, Priyanka, Bonner, Julia Maeve, Kory, Nora, Boland, Sebastian, Arczewska, Aleksandra A, Ralvenius, William T, Akay, Leyla, Lockshin, Elana, He, Liang, Milo, Blerta, Graziosi, Agnese, Baru, Valeriya, Lewis, Caroline A, Kellis, Manolis, Sabatini, David M, Tsai, Li-Huei, Lindquist, Susan

“…The allele of the apolipoprotein E gene ( ) has been established as a genetic risk factor for many diseases including cardiovascular diseases and Alzheimer's…”
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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types by Lin, Yuan-Ta, Seo, Jinsoo, Gao, Fan, Feldman, Heather M., Wen, Hsin-Lan, Penney, Jay, Cam, Hugh P., Gjoneska, Elizabeta, Raja, Waseem K., Cheng, Jemmie, Rueda, Richard, Kritskiy, Oleg, Abdurrob, Fatema, Peng, Zhuyu, Milo, Blerta, Yu, Chung Jong, Elmsaouri, Sara, Dey, Dilip, Ko, Tak, Yankner, Bruce A., Tsai, Li-Huei

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F1‐07‐04: USING HUMAN IPSC MODELS TO PROBE TREM2 FUNCTION by Penney, Jay, Elmsaouri, Sara, Milo, Blerta, Gao, Fan, Tsai, Li-Huei

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USING HUMAN IPSC MODELS TO PROBE TREM2 FUNCTION by Penney, Jay, Elmsaouri, Sara, Milo, Blerta, Gao, Fan, Tsai, Li-Huei

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Improving the therapeutic efficacy of mesenchymal stromal cells to restore perfusion in critical limb ischemia through pulsed focused ultrasound by Tebebi, Pamela A., Kim, Saejeong J., Williams, Rashida A., Milo, Blerta, Frenkel, Victor, Burks, Scott R., Frank, Joseph A.

“…Mesenchymal stem cells (MSC) are promising therapeutics for critical limb ischemia (CLI). Mechanotransduction from pulsed focused ultrasound (pFUS) upregulates…”
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Enhanced stem cell and progenitor cell homing following IV injection to skeletal muscle in a murine model of muscular dystrophy induced by pulsed focused ultrasound (pFUS) by Frank, Joseph A, Nguyen, Ben, Bresler, Michele, Milo, Blerta, Kim, Sage, Burks, Scott

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