Search Results - "Milne, Mark"

The Development and Testing of a Patient Decision Aid for Individuals with Homologous Recombinant Proficient Ovarian Cancer Who Are Considering Niraparib Maintenance Therapy by Hopkins, Laura, Carey, Mark, Brown, Linda, McCrea, Sabryna, Milne, Mark, Tokaryk, Dawne, Stacey, Dawn

“…New treatments for ovarian cancer are available that require trade-offs between progression-free survival and quality of life. The aim of this study was to…”
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The development of peptide-boron difluoride formazanate conjugates as fluorescence imaging agents by Sharma, Neha, Barbon, Stephanie M, Lalonde, Tyler, Maar, Ryan R, Milne, Mark, Gilroy, Joe B, Luyt, Leonard G

“…Two new fluorescence imaging probes have been synthesized by incorporating a versatile alkyne-substituted boron difluoride formazanate precursor with peptides…”
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Synthesis and characterization of new ferrocene peptide conjugates by Drexler, Cailin, Milne, Mark, Morgan, Erin, Jennings, Michael, Kraatz, H-B

“…Three classes of diamine linked ferrocene (Fc)-conjugates were prepared and their properties were investigates in solution and the solid state: (a) acyclic…”
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A Study of the Differences in Spatial Visualisation in First Year Engineering Students and the Development of Training Support Methods by Milne, Mark

“…It was observed during teaching of engineering drawing, that some students had difficulty visualising objects in three dimensional space, and particularly…”
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Invitation methods for Indigenous New Zealand Māori in lung cancer screening: Protocol for a pragmatic cluster randomized controlled trial by Parker, Kate, Colhoun, Sarah, Bartholomew, Karen, Sandiford, Peter, Lewis, Chris, Milne, David, McKeage, Mark, McKree Jansen, Rawiri, Fong, Kwun M, Marshall, Henry, Tammemägi, Martin, Rankin, Nicole M, Hotu, Sandra, Young, Robert, Hopkins, Raewyn, Walker, Natalie, Brown, Rachel, Crengle, Sue

“…Lung cancer screening can significantly reduce mortality from lung cancer. Further evidence about how to optimize lung cancer screening for specific…”
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Corrigendum to “A truncated RHAMM protein for discovering novel therapeutic peptides” [Bioorg. Med. Chem. 26 (2018) 5194–5203] by Hauser-Kawaguchi, Alexandra, Tolg, Cornelia, Peart, Teresa, Milne, Mark, Turley, Eva A., Luyt, Leonard G.

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Nuclear spin hyperpolarization of the solvent using signal amplification by reversible exchange (SABRE) by Moreno, Karlos X., Nasr, Khaled, Milne, Mark, Sherry, A. Dean, Goux, Warren J.

“…[Display omitted] •Under acidic conditions the solvent can be hyperpolarized using SABRE.•Solvent hyperpolarization takes place by chemical exchange.•The…”
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Front Cover: Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a (ChemMedChem 20/2019) by Lalonde, Tyler, Fowkes, Milan M., Hou, Jinqiang, Thibeault, Pierre E., Milne, Mark, Dhanvantari, Savita, Ramachandran, Rithwik, Luyt, Leonard G.

“…The Front Cover depicts the unique interaction between a tyrosine residue of our peptidomimetic and Arg283 in the binding pocket of the ghrelin receptor. This…”
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A truncated RHAMM protein for discovering novel therapeutic peptides by Hauser-Kawaguchi, Alexandra, Tolg, Cornelia, Peart, Teresa, Milne, Mark, Turley, Eva A., Luyt, Leonard G.

“…[Display omitted] •7 kDa RHAMM is a chemically synthesized, truncated receptor of native 95 kDa RHAMM.•7 kDa RHAMM is biologically active and can be…”
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High Affinity Fluorescent Probe for Proteinase-Activated Receptor 2 (PAR2) by LeSarge, Jordan C, Thibeault, Pierre, Milne, Mark, Ramachandran, Rithwik, Luyt, Leonard G

“…PAR2 is a proteolytically activated G protein-coupled receptor (GPCR) that is implicated in various cancers and inflammatory diseases. Ligands with low…”
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Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a by Lalonde, Tyler, Fowkes, Milan M., Hou, Jinqiang, Thibeault, Pierre E., Milne, Mark, Dhanvantari, Savita, Ramachandran, Rithwik, Luyt, Leonard G.

“…The growth hormone secretagogue receptor type 1a (GHS‐R1a) is a class A rhodopsin‐like G protein coupled receptor (GPCR) that is expressed in a variety of…”
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In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage by Ruiz, A., Duarte, A., Bravo, D., Ramos Gavilá, E., Zhang, C., Cowman, M.K., Kirsch, T., Milne, M., Luyt, L.G., Raya, J.G.

“…One driving factor in the progression to posttraumatic osteoarthritis (PTOA) is the perpetuation of the inflammatory response to injury into chronic…”
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Synthesis of a poly(Gd( iii )-DOTA)–PNA conjugate as a potential MRI contrast agent via post-synthetic click chemistry functionalization by Wang, Xiaoxiao, Milne, Mark, Martínez, Francisco, Scholl, Timothy J., Hudson, Robert H. E.

“…Herein we present a method for the simultaneous, multiple conjugation of alkynyl-(Gd( iii )-DOTA) moieties to a PNA oligomer possessing a domain of azide…”
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Introduction of Peripheral Carboxylates to Decrease the Charge on Tm(3+) DOTAM-Alkyl Complexes: Implications for Detection Sensitivity and in Vivo Toxicity of PARACEST MRI Contrast Agents by Suchý, Mojmír, Milne, Mark, Elmehriki, Adam A H, McVicar, Nevin, Li, Alex X, Bartha, Robert, Hudson, Robert H E

“…A series of structurally modified Tm(3+) DOTAM-alkyl complexes as potential PARACEST MRI contrast agents has been synthesized with the aim to decrease the…”
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Introduction of Peripheral Carboxylates to Decrease the Charge on Tm 3+ DOTAM-Alkyl Complexes: Implications for Detection Sensitivity and in Vivo Toxicity of PARACEST MRI Contrast Agents by Suchý, Mojmír, Milne, Mark, Elmehriki, Adam A. H., McVicar, Nevin, Li, Alex X., Bartha, Robert, Hudson, Robert H. E.

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Dysprosium complexes of DO3A-monoanilides: an investigation of electronic effects on their relaxometric and amide-based PARACEST properties by Lewis, Melissa M, Milne, Mark, Bartha, Robert, Hudson, Robert H.E

“…A series of 1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate monoamide (DO3A-monoanilide) complexes [Dy.sup.3+] and [Tm.sup.3+] were prepared and their…”
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Maximizing T sub(2)-exchange in Dy super(3+)DOTA-(amide) sub(X) chelates: Fine-tuning the water molecule exchange rate for enhanced T sub(2) contrast in MRI by Soesbe, Todd C, Ratnakar, SJames, Milne, Mark, Zhang, Shanrong, Do, Quyen N, Kovacs, Zoltan, Sherry, ADean

“…Purpose The water molecule exchange rates in a series of DyDOTA-(amide) sub(X) chelates were fine-tuned to maximize the effects of T sub(2)-exchange line…”
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ParaCEST MRI contrast agents capable of derivatization via"click" chemistry by Milne, Mark, Chicas, Kirby, Li, Alex, Bartha, Robert, Hudson, Robert H E

“…A comprehensive series of lanthanide chelates has been prepared with a tetrapropargyl DOTAM type ligand. The complexes have been characterized by a combination…”
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Introduction of Peripheral Carboxylates to Decrease the Charge on Tm3+ DOTAM-Alkyl Complexes: Implications for Detection Sensitivity and in Vivo Toxicity of PARACEST MRI Contrast Agents by Suchý, Mojmír, Milne, Mark, Elmehriki, Adam A. H, McVicar, Nevin, Li, Alex X, Bartha, Robert, Hudson, Robert H. E

“…A series of structurally modified Tm3+ DOTAM-alkyl complexes as potential PARACEST MRI contrast agents has been synthesized with the aim to decrease the…”
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Maximizing T 2 ‐exchange in Dy 3+ DOTA‐(amide) X chelates: Fine‐tuning the water molecule exchange rate for enhanced T 2 contrast in MRI by Soesbe, Todd C., Ratnakar, S. James, Milne, Mark, Zhang, Shanrong, Do, Quyen N., Kovacs, Zoltan, Sherry, A. Dean

“…Purpose The water molecule exchange rates in a series of DyDOTA‐(amide) X chelates were fine‐tuned to maximize the effects of T 2 ‐exchange line broadening and…”
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