Search Results - "Mills, Matthew N"
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Trastuzumab Emtansine (T-DM1) and stereotactic radiation in the management of HER2+ breast cancer brain metastases
Published in BMC cancer (04-03-2021)“…Due to recent concerns about the toxicity of trastuzumab emtansine (T-DM1) with stereotactic radiation, we assessed our institutional outcomes treating…”
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Capecitabine and stereotactic radiation in the management of breast cancer brain metastases
Published in BMC cancer (15-05-2021)“…Little is known about the safety and efficacy of concurrent capecitabine and stereotactic radiotherapy in the setting of breast cancer brain metastases (BCBM)…”
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Prediction of radiologic outcome-optimized dose plans and post-treatment magnetic resonance images: A proof-of-concept study in breast cancer brain metastases treated with stereotactic radiosurgery
Published in Physics and imaging in radiation oncology (01-07-2024)“…Information in multiparametric Magnetic Resonance (mpMR) images is relatable to voxel-level tumor response to Radiation Treatment (RT). We have investigated a…”
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Novel Definitive Hypofractionated Accelerated Radiation Dose-painting (HARD) for Unresected Soft Tissue Sarcomas
Published in Advances in radiation oncology (01-04-2024)“…Soft tissue sarcomas (STS) are historically radioresistant, with surgery being an integral component of their treatment. With their low α/β, STS may be more…”
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Multi-institutional report of trastuzumab deruxtecan and stereotactic radiosurgery for HER2 positive and HER2-low breast cancer brain metastases
Published in NPJ breast cancer (21-11-2024)“…Trastuzumab-deruxtecan (T-DXd) has demonstrated intracranial efficacy; however, safety and efficacy data remains limited with stereotactic radiosurgery (SRS)…”
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Miliary breast cancer brain metastasis: a rare and aggressive form of central nervous system metastasis
Published in British journal of cancer (27-10-2020)“…Summary Although breast cancer brain metastasis is an increasingly common occurrence, relatively little is known about miliary brain metastases, a rare subtype…”
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Histologic heterogeneity of triple negative breast cancer: A National Cancer Centre Database analysis
Published in European journal of cancer (1990) (01-07-2018)“…Triple negative breast cancer (TNBC) is an aggressive disease, but recent studies have identified heterogeneity in patient outcomes. However, the utility of…”
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Management of brain metastases in breast cancer: a review of current practices and emerging treatments
Published in Breast cancer research and treatment (01-04-2020)“…Purpose Breast cancer brain metastases (BCBM) are becoming an increasingly common diagnosis due to improved systemic control and more routine surveillance…”
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Neoadjuvant Simultaneous Integrated Boost Radiation Therapy Improves Clinical Outcomes for Retroperitoneal Sarcoma
Published in International journal of radiation oncology, biology, physics (01-09-2023)“…Neoadjuvant radiation therapy (RT) with standard techniques (ST) offers a modest benefit in retroperitoneal sarcoma (RPS). As the high-risk region (HRR) at…”
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Hypofractionated accelerated radiation dose-painting (HARD) improves outcomes in unresected soft-tissue sarcoma
Published in Radiotherapy and oncology (01-01-2025)“…•The HARD regimen for unresected STS resulted in excellent local control.•HARD improved local control compared to standard fractionation.•HARD was safe and not…”
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Evolving management of HER2+ breast cancer brain metastases and leptomeningeal disease
Published in Journal of neuro-oncology (01-04-2022)“…Patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer are at a particularly high risk of breast cancer brain metastasis (BCBM)…”
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Tucatinib and stereotactic radiosurgery in the management of HER2 positive breast cancer brain metastases
Published in Journal of neuro-oncology (01-08-2023)“…Purpose HER2-positive breast cancer has a high risk of brain metastasis. Stereotactic radiosurgery (SRS) is standard of care for limited brain metastases…”
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Clinical outcomes of non-small cell lung cancer brain metastases treated with stereotactic radiosurgery and immune checkpoint inhibitors, EGFR tyrosine kinase inhibitors, chemotherapy and immune checkpoint inhibitors, or chemotherapy alone
Published in Journal of neurosurgery (01-06-2023)“…Immune checkpoint inhibitors (ICIs) and epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are commonly used in the systemic management of…”
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Stereotactic Body Radiation Therapy in Oligometastatic Uterine Cancer: Clinical Outcomes and Toxicity
Published in Cancer investigation (20-10-2020)“…We report on clinical outcomes in patients with oligometastatic uterine cancer treated with stereotactic body radiation therapy (SBRT). Twenty-seven patients…”
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Increased Risk for Ipsilateral Breast Tumor Recurrence in Invasive Lobular Carcinoma after Accelerated Partial Breast Irradiation Brachytherapy
Published in The oncologist (Dayton, Ohio) (01-11-2021)“…Background The suitability criteria for accelerated partial breast irradiation (APBI) from the American Brachytherapy Society (ABS), American Society for…”
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Clinical Outcomes of Patients with Non-Small Cell Lung Cancer Leptomeningeal Disease Following Receipt of EGFR-Targeted Therapy, Immune-Checkpoint Blockade, Intrathecal Chemotherapy, or Radiation Therapy Alone
Published in Clinical lung cancer (01-07-2024)“…•Patients with NSCLC LMD have a poor prognosis, with a 6-month OS of 35%.•EGFR-positive NSCLC LMD who received targeted therapy have improved OS.•EGFR-positive…”
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Clinical outcomes of melanoma brain metastases treated with nivolumab and ipilimumab alone versus nivolumab and ipilimumab with stereotactic radiosurgery
Published in Journal of neuro-oncology (01-02-2024)“…Purpose Upfront dual checkpoint blockade with immune checkpoint inhibitors (ICI) has demonstrated efficacy for treating melanoma brain metastases (MBM) in…”
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The Prognostic Role of Pretreatment Neutrophil to Lymphocyte Ratio (NLR) in Malignant Adrenal Lesions Treated With Stereotactic Body Radiation Therapy (SBRT)
Published in American journal of clinical oncology (01-12-2019)“…The objective of this study was to evaluate a single institution's experience with stereotactic body radiotherapy (SBRT) in treating malignant adrenal lesions,…”
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The presentation of brain metastases in melanoma, non-small cell lung cancer, and breast cancer and potential implications for screening brain MRIs
Published in Breast cancer research and treatment (2022)“…Purpose This study assessed the presentation and institutional outcomes treating brain metastases (BM) of breast cancer (BC), non-small cell lung cancer…”
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