Search Results - "Mills, Kenna R."

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults by Jain, Nitin, Roberts, Kathryn G., Jabbour, Elias, Patel, Keyur, Eterovic, Agda Karina, Chen, Ken, Zweidler-McKay, Patrick, Lu, Xinyan, Fawcett, Gloria, Wang, Sa A., Konoplev, Sergej, Harvey, Richard C., Chen, I-Ming, Payne-Turner, Debbie, Valentine, Marcus, Thomas, Deborah, Garcia-Manero, Guillermo, Ravandi, Farhad, Cortes, Jorge, Kornblau, Steven, O'Brien, Susan, Pierce, Sherry, Jorgensen, Jeffrey, Shaw, Kenna R.Mills, Willman, Cheryl L., Mullighan, Charles G., Kantarjian, Hagop, Konopleva, Marina

“…Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk subtype of ALL in children. There are conflicting data on the incidence and…”
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Characteristics of percutaneous core biopsies adequate for next generation genomic sequencing by Sabir, Sharjeel H, Krishnamurthy, Savitri, Gupta, Sanjay, Mills, Gordon B, Wei, Wei, Cortes, Andrea C, Mills Shaw, Kenna R, Luthra, Rajyalakshmi, Wallace, Michael J

“…Determine the characteristics of percutaneous core biopsies that are adequate for a next generation sequencing (NGS) genomic panel. All patients undergoing…”
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Targeting TRK family proteins in cancer by Khotskaya, Yekaterina B, Holla, Vijaykumar R, Farago, Anna F, Mills Shaw, Kenna R, Meric-Bernstam, Funda, Hong, David S

“…The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and NTRK3 genes, respectively. Binding…”
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A Deep Learning Framework for Predicting Response to Therapy in Cancer by Sakellaropoulos, Theodore, Vougas, Konstantinos, Narang, Sonali, Koinis, Filippos, Kotsinas, Athanassios, Polyzos, Alexander, Moss, Tyler J., Piha-Paul, Sarina, Zhou, Hua, Kardala, Eleni, Damianidou, Eleni, Alexopoulos, Leonidas G., Aifantis, Iannis, Townsend, Paul A., Panayiotidis, Mihalis I., Sfikakis, Petros, Bartek, Jiri, Fitzgerald, Rebecca C., Thanos, Dimitris, Mills Shaw, Kenna R., Petty, Russell, Tsirigos, Aristotelis, Gorgoulis, Vassilis G.

“…A major challenge in cancer treatment is predicting clinical response to anti-cancer drugs on a personalized basis. Using a pharmacogenomics database of 1,001…”
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Essay Contest Reveals Misconceptions of High School Students in Genetics Content by Mills Shaw, Kenna R, Van Horne, Katie, Zhang, Hubert, Boughman, Joann

“…National educational organizations have called upon scientists to become involved in K-12 education reform. From sporadic interaction with students to more…”
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The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini by Debnath, Jayanta, Mills, Kenna R., Collins, Nicole L., Reginato, Mauricio J., Muthuswamy, Senthil K., Brugge, Joan S.

“…We have utilized in vitro three-dimensional epithelial cell cultures to analyze the role of apoptosis in the formation and maintenance of a hollow glandular…”
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Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Is Required for Induction of Autophagy during Lumen Formation in vitro by Mills, Kenna R., Reginato, Mauricio, Debnath, Jayanta, Queenan, Bridget, Brugge, Joan S.

“…The molecular events regulating the elimination of cells to create a hollow lumen during tissue development are poorly understood. By using an in vitro…”
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Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer by Pairawan, Seyed, Hess, Kenneth R, Janku, Filip, Sanchez, Nora S, Mills Shaw, Kenna R, Eng, Cathy, Damodaran, Senthilkumar, Javle, Milind, Kaseb, Ahmed O, Hong, David S, Subbiah, Vivek, Fu, Siqing, Fogelman, David R, Raymond, Victoria M, Lanman, Richard B, Meric-Bernstam, Funda

“…Physicians are expected to assess prognosis both for patient counseling and for determining suitability for clinical trials. Increasingly, cell-free…”
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Prospective Clinical Sequencing of Adult Glioma by Zheng, Siyuan, Alfaro-Munoz, Kristin, Wei, Wei, Wang, Xiaojing, Wang, Fang, Eterovic, Agda Karina, Shaw, Kenna R Mills, Meric-Bernstam, Funda, Fuller, Gregory N, Chen, Ken, Verhaak, Roel G, Mills, Gordon B, Yung, W K Alfred, Weathers, Shiao-Pei, de Groot, John F

“…Malignant gliomas are a group of intracranial cancers associated with disproportionately high mortality and morbidity. Here, we report ultradeep targeted…”
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Next-Generation Sequencing and Result Interpretation in Clinical Oncology: Challenges of Personalized Cancer Therapy by Khotskaya, Yekaterina B, Mills, Gordon B, Mills Shaw, Kenna R

“…The tools of next-generation sequencing (NGS) technology, such as targeted sequencing of candidate cancer genes and whole-exome and -genome sequencing, coupled…”
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Actionability classification of variants of unknown significance correlates with functional effect by Johnson, Amber, Ng, Patrick Kwok-Shing, Kahle, Michael, Castillo, Julia, Amador, Bianca, Wang, Yujia, Zeng, Jia, Holla, Vijaykumar, Vu, Thuy, Su, Fei, Kim, Sun-Hee, Conway, Tara, Jiang, Xianli, Chen, Ken, Shaw, Kenna R. Mills, Yap, Timothy A., Rodon, Jordi, Mills, Gordon B., Meric-Bernstam, Funda

“…Genomically-informed therapy requires consideration of the functional impact of genomic alterations on protein expression and/or function. However, a…”
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Bim Regulation of Lumen Formation in Cultured Mammary Epithelial Acini Is Targeted by Oncogenes by Reginato, Mauricio J., Mills, Kenna R., Becker, Esther B. E., Lynch, Danielle K., Bonni, Azad, Muthuswamy, Senthil K., Brugge, Joan S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Use of three-dimensional basement membrane cultures to model oncogene-induced changes in mammary epithelial morphogenesis by Shaw, Kenna R Mills, Wrobel, Carolyn N, Brugge, Joan S

“…The development of breast carcinomas involves a complex set of phenotypic alterations in breast epithelial cells and the surrounding microenvironment. While…”
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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia by Ley, Timothy J, Miller, Christopher, Ding, Li, Raphael, Benjamin J, Mungall, Andrew J, Robertson, A Gordon, Hoadley, Katherine, Triche, Jr, Timothy J, Laird, Peter W, Baty, Jack D, Fulton, Lucinda L, Fulton, Robert, Heath, Sharon E, Kalicki-Veizer, Joelle, Kandoth, Cyriac, Klco, Jeffery M, Koboldt, Daniel C, Kanchi, Krishna-Latha, Kulkarni, Shashikant, Lamprecht, Tamara L, Larson, David E, Lin, Ling, Lu, Charles, McLellan, Michael D, McMichael, Joshua F, Payton, Jacqueline, Schmidt, Heather, Spencer, David H, Tomasson, Michael H, Wallis, John W, Wartman, Lukas D, Watson, Mark A, Welch, John, Wendl, Michael C, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Butterfield, Yaron, Chiu, Readman, Chu, Andy, Chuah, Eric, Chun, Hye-Jung, Corbett, Richard, Dhalla, Noreen, Guin, Ranabir, He, An, Hirst, Carrie, Hirst, Martin, Holt, Robert A, Jones, Steven, Karsan, Aly, Lee, Darlene, Li, Haiyan I, Marra, Marco A, Mayo, Michael, Moore, Richard A, Mungall, Karen, Parker, Jeremy, Pleasance, Erin, Plettner, Patrick, Schein, Jacquie, Stoll, Dominik, Swanson, Lucas, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wye, Natasja, Zhao, Yongjun, Gabriel, Stacey, Getz, Gad, Sougnez, Carrie, Zou, Lihua, Leiserson, Mark D M, Vandin, Fabio, Wu, Hsin-Ta, Applebaum, Frederick, Baylin, Stephen B, Akbani, Rehan, Broom, Bradley M, Chen, Ken, Motter, Thomas C, Nguyen, Khanh, Weinstein, John N, Zhang, Nianziang, Ferguson, Martin L, Adams, Christopher, Black, Aaron, Bowen, Jay, Gastier-Foster, Julie, Grossman, Thomas, Lichtenberg, Tara, Wise, Lisa, Davidsen, Tanja, Demchok, John A, Shaw, Kenna R Mills, Sheth, Margi, Sofia, Heidi J, Yang, Liming, Downing, James R, Eley, Greg

“…More than 25% of patients with AML carry no mutations in genes known to be associated with leukemia. Analyses of genomes, transcriptomes, and methylomes of AML…”
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Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations by Somaiah, Neeta, Beird, Hannah C, Barbo, Andrea, Song, Juhee, Mills Shaw, Kenna R, Wang, Wei-Lien, Eterovic, Karina, Chen, Ken, Lazar, Alexander, Conley, Anthony P, Ravi, Vinod, Hwu, Patrick, Futreal, Andrew, Simon, George, Meric-Bernstam, Funda, Hong, David

“…Well-differentiated/dedifferentiated liposarcoma is a common soft tissue sarcoma with approximately 1500 new cases per year. Surgery is the mainstay of…”
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Physician interpretation of genomic test results and treatment selection by Brusco, Lauren L., Wathoo, Chetna, Mills Shaw, Kenna R., Holla, Vijaykumar R., Bailey, Ann M., Johnson, Amber M., Khotskaya, Yekaterina B., Litzenburger, Beate C., Sanchez, Nora S., Zeng, Jia, Bernstam, Elmer V., Eng, Cathy, Kee, Bryan K., Amaria, Rodabe N., Routbort, Mark J., Mills, Gordon B., Mendelsohn, John, Meric‐Bernstam, Funda

“…BACKGROUND Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current…”
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The Status and Impact of Clinical Tumor Genome Sequencing by Shaw, Kenna R. Mills, Maitra, Anirban

“…Since the discovery that DNA alterations initiate tumorigenesis, scientists and clinicians have been exploring ways to counter these changes with targeted…”
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OCTANE: Oncology Clinical Trial Annotation Engine by Zeng, Jia, Shufean, Md Abu, Khotskaya, Yekaterina, Yang, Dong, Kahle, Michael, Johnson, Amber, Holla, Vijaykumar, Sánchez, Nora, Mills Shaw, Kenna R, Bernstam, Elmer V, Meric-Bernstam, Funda

“…Many targeted therapies are currently available only via clinical trials. Therefore, routine precision oncology using biomarker-based assignment to drug…”
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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA by Kaseb, Ahmed O, Sánchez, Nora S, Sen, Shiraj, Kelley, Robin K, Tan, Benjamin, Bocobo, Andrea G, Lim, Kian H, Abdel-Wahab, Reham, Uemura, Marc, Pestana, Roberto Carmagnani, Qiao, Wei, Xiao, Lianchun, Morris, Jeffrey, Amin, Hesham M, Hassan, Manal M, Rashid, Asif, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Mills-Shaw, Kenna R, George, Bhawana, Haque, Abedul, Raghav, Kanwal P S, Wolff, Robert A, Yao, James C, Meric-Bernstam, Funda, Ikeda, Sadakatsu, Kurzrock, Razelle

“…Molecular profiling has been used to select patients for targeted therapy and determine prognosis. Noninvasive strategies are critical to hepatocellular…”
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Correction: A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory by Arango, Natalia Paez, Brusco, Lauren, Shaw, Kenna R Mills, Chen, Ken, Eterovic, Agda Karina, Holla, Vijaykumar, Johnson, Amber, Litzenburger, Beate, Khotskaya, Yekaterina B, Sanchez, Nora, Bailey, Ann, Zheng, Xiaofeng, Horombe, Chacha, Kopetz, Scott, Farhangfar, Carol J, Routbort, Mark, Broaddus, Russell, Bernstam, Elmer V, Mendelsohn, John, Mills, Gordon B, Meric-Bernstam, Funda

“…[This corrects the article DOI: 10.18632/oncotarget.16018.]…”
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