Search Results - "Milligan, J."

Photophysiological Expressions of Iron Stress in Phytoplankton by Behrenfeld, Michael J, Milligan, Allen J

“…Iron is essential for all life, but it is particularly important to photoautotrophs because of the many iron-dependent electron transport components in…”
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Additive Manufacturing of Al-12Si Alloy Via Pulsed Selective Laser Melting by Chou, R., Milligan, J., Paliwal, M., Brochu, M.

“…Additive manufacturing (AM) of metallic materials is experiencing a research and commercialization craze in almost all industrial sectors. However, to date, AM…”
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The CAFE model: A net production model for global ocean phytoplankton by Silsbe, Greg M., Behrenfeld, Michael J., Halsey, Kimberly H., Milligan, Allen J., Westberry, Toby K.

“…The Carbon, Absorption, and Fluorescence Euphotic‐resolving (CAFE) net primary production model is an adaptable framework for advancing global ocean…”
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Quinidine in the treatment of KCNT1-positive epilepsies by Mikati, Mohamad A, Jiang, Yong-hui, Carboni, Michael, Shashi, Vandana, Petrovski, Slave, Spillmann, Rebecca, Milligan, Carol J., Li, Melody, Grefe, Annette, McConkie, Allyn, Berkovic, Samuel, Scheffer, Ingrid, Mullen, Saul, Bonner, Melanie, Petrou, Steven, Goldstein, David

“…We report 2 patients with drug‐resistant epilepsy caused by KCNT1 mutations who were treated with quinidine. Both mutations manifested gain of function in…”
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Revaluating ocean warming impacts on global phytoplankton by Behrenfeld, Michael J., O’Malley, Robert T., Boss, Emmanuel S., Westberry, Toby K., Graff, Jason R., Halsey, Kimberly H., Milligan, Allen J., Siegel, David A., Brown, Matthew B.

“…Global satellite observations document expansions of the low-chlorophyll central ocean gyres and an overall inverse relationship between anomalies in sea…”
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Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death by Richards, Kay L., Milligan, Carol J., Richardson, Robert J., Jancovski, Nikola, Grunnet, Morten, Jacobson, Laura H., Undheim, Eivind A. B., Mobli, Mehdi, Chow, Chun Yuen, Herzig, Volker, Csoti, Agota, Panyi, Gyorgy, Reid, Christopher A., King, Glenn F., Petrou, Steven

“…Dravet syndrome is a catastrophic, pharmacoresistant epileptic encephalopathy. Disease onset occurs in the first year of life, followed by developmental delay…”
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KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine by Milligan, Carol J., Li, Melody, Gazina, Elena V., Heron, Sarah E., Nair, Umesh, Trager, Chantel, Reid, Christopher A., Venkat, Anu, Younkin, Donald P., Dlugos, Dennis J., Petrovski, Slavé, Goldstein, David B., Dibbens, Leanne M., Scheffer, Ingrid E., Berkovic, Samuel F., Petrou, Steven

“…Objective Mutations in KCNT1 have been implicated in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) and epilepsy of infancy with migrating focal…”
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Analytical phytoplankton carbon measurements spanning diverse ecosystems by Graff, Jason R., Westberry, Toby K., Milligan, Allen J., Brown, Matthew B., Dall’Olmo, Giorgio, Dongen-Vogels, Virginie van, Reifel, Kristen M., Behrenfeld, Michael J.

“…The measurement of phytoplankton carbon (Cphyto) in the field has been a long-sought but elusive goal in oceanography. Proxy measurements of Cphyto have been…”
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How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines? by Laverty, HG, Benson, C, Cartwright, EJ, Cross, MJ, Garland, C, Hammond, T, Holloway, C, McMahon, N, Milligan, J, Park, BK, Pirmohamed, M, Pollard, C, Radford, J, Roome, N, Sager, P, Singh, S, Suter, T, Suter, W, Trafford, A, Volders, PGA, Wallis, R, Weaver, R, York, M, Valentin, JP

“…Given that cardiovascular safety liabilities remain a major cause of drug attrition during preclinical and clinical development, adverse drug reactions, and…”
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Monitoring of a hip surveillance programme protects infants from radiation and surgical intervention by Milligan, David J, Cosgrove, Aidan P

“…To monitor the performance of services for developmental dysplasia of the hip (DDH) in Northern Ireland and identify potential improvements to enhance quality…”
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Evolved physiological responses of phytoplankton to their integrated growth environment by Behrenfeld, Michael J, Halsey, Kimberly H, Milligan, Allen J

“…Phytoplankton growth and productivity relies on light, multiple nutrients and temperature. These combined factors constitute the ‘integrated growth…”
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Nanocrystalline eutectic Al–Si alloy produced by cryomilling by Milligan, J., Vintila, R., Brochu, M.

“…A nanocrystalline Al–Si eutectic alloy was produced by mechanical attrition under cryogenic conditions. The resulting alloy was characterized using X-ray…”
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Membrane Lipids of Symbiotic Algae Are Diagnostic of Sensitivity to Thermal Bleaching in Corals by Tchernov, Dan, Gorbunov, Maxim Y., de Vargas, Colomban, Yadav, Swati Narayan, Milligan, Allen J., Häggblom, Max, Falkowski, Paul G., Field, Christopher B.

“…Over the past three decades, massive bleaching events of zoox-anthellate corals have been documented across the range of global distribution. Although the…”
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Integrated analysis of risks of coastal flooding and cliff erosion under scenarios of long term change by Dawson, R. J., Dickson, M. E., Nicholls, R. J., Hall, J. W., Walkden, M. J. A., Stansby, P. K., Mokrech, M., Richards, J., Zhou, J., Milligan, J., Jordan, A., Pearson, S., Rees, J., Bates, P. D., Koukoulas, S., Watkinson, A. R.

“…The risks to human populations in coastal areas are changing due to climate and socio-economic changes, and these trends are predicted to accelerate during the…”
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Substandard and falsified anti-tuberculosis drugs: a preliminary field analysis by Bate, R., Jensen, P., Hess, K., Mooney, L., Milligan, J.

“…SETTING: Pharmacies in 19 cities in Angola, Brazil, China, Democratic Republic of Congo, Egypt, Ethiopia, Ghana, India (n = 3), Kenya, Nigeria, Russia, Rwanda,…”
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Beyond CBD: Inhibitory effects of lesser studied phytocannabinoids on human voltage-gated sodium channels by Milligan, Carol J, Anderson, Lyndsey L, McGregor, Iain S, Arnold, Jonathon C, Petrou, Steven

“…Cannabis contains cannabidiol (CBD), the main non-psychoactive phytocannabinoid, but also many other phytocannabinoids that have therapeutic potential in the…”
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Physiological optimization underlies growth rate-independent chlorophyll-specific gross and net primary production by Halsey, Kimberly H, Milligan, Allen J, Behrenfeld, Michael J

“…Characterization of physiological variability in phytoplankton photosynthetic efficiencies is one of the greatest challenges in assessing ocean net primary…”
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Rise of Oxygen over the Past 205 Million Years and the Evolution of Large Placental Mammals by Falkowski, Paul G, Katz, Miriam E, Milligan, Allen J, Fennel, Katja, Cramer, Benjamin S, Aubry, Marie Pierre, Berner, Robert A, Novacek, Michael J, Zapol, Warren M

“…On the basis of a carbon isotopic record of both marine carbonates and organic matter from the Triassic-Jurassic boundary to the present, we modeled oxygen…”
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Impact properties of half stress-relieved and hot isostatic pressed Ti–6Al–4V components fabricated by laser powder bed fusion by Keshavarz, M.K., Sikan, F., Boutet, C.E., Milligan, J., Bois-Brochu, A., Brochu, M.

“…This study focuses on the impact properties of Ti–6Al–4V produced by LPBF using un-notched Charpy impact testing. The effects of the build orientation, impact…”
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Cladding AA7075 with a cryomilled Al―12Si alloy using spark plasma sintering by MILLIGAN, J, BROCHU, M

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