Search Results - "Millership, J S"

Public awareness and views on unlicensed use of medicines in children by Mukattash, T. L., Millership, J. S., Collier, P. S., McElnay, J. C.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • There is increasing concern about the use of those medicines in children which have not been fully studied and…”
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Development and validation of an HPLC method for the determination of spironolactone and its metabolites in paediatric plasma samples by Sandall, J.M., Millership, J.S., Collier, P.S., McElnay, J.C.

“…An HPLC method has been developed and validated for the determination of spironolactone, 7α-thiomethylspirolactone and canrenone in paediatric plasma samples…”
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Intravenous indometacin in preterm infants with symptomatic patent ductus arteriosus. A population pharmacokinetic study by Smyth, J. M., Collier, P. S., Darwish, M., Millership, J. S., Halliday, H. L., Petersen, S., McElnay, J. C.

“…Aims To characterize the population pharmacokinetics of indometacin in preterm infants with symptomatic patent ductus arteriosus and to investigate the…”
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Liquid chromatographic determination including simultaneous “on-cartridge” separation of ranitidine cisapride drug combinations from paediatric plasma samples using an automated solid-phase extraction procedure by Hare, L.G., Mitchel, D.S., Millership, J.S., Collier, P.S., McElnay, J.C., Shields, M.D., Carson, D.J., Fair, R.

“…HPLC methodology was investigated for the simultaneous determination of cisapride and ranitidine in small volume paediatric plasma samples. Such a simultaneous…”
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A simple bioanalytical method for the quantification of antiepileptic drugs in dried blood spots by Shah, N. Mohamed, Hawwa, A.F., Millership, J.S., Collier, P.S., McElnay, J.C.

“…► We report a simple method for the analysis of four antiepileptic drugs in DBS samples. ► The method was applied to DBS samples collected from children with…”
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Chiral aspects of the human metabolism of ethosuximide by Millership, J. S., Mifsud, J., Galea, D., McRoberts, W. C., Hamilton, J. T. G.

“…Ethosuximide is a chiral drug substance primarily indicated for the treatment of absence seizures. This drug is used clinically as the racemate. The human…”
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The use of hydrophilic lipophilic balanced (HLB) copolymer SPE cartridges for the extraction of diclofenac from small volume paediatric plasma samples by MILLERSHIP, J. S, HARE, L. G, FARRY, M, COLLIER, P. S, MCELNAY, J. C, SHIELDS, M. D, CARSON, D. J

“…The extraction of diclofenac from spiked aqueous and plasma samples by liquid-liquid extraction (LLE) and solid phase extraction (SPE) methods is compared. The…”
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The pharmacokinetics of ethosuximide enantiomers in the rat by Mifsud, J., Collier, P.S., Millership, J.S.

“…A chiral gas chromatographic assay previously developed for quantitative analysis of ethosuximide and its major metabolites in rat urine has been adapted for…”
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Commonly used chiral drugs: a survey by Millership, J S, Fitzpatrick, A

“…Initial results of a comparative survey of commonly used chiral drugs are presented. The survey considered the differences between drugs used in 1982 with…”
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Quantification of urinary excretion of ethosuximide enantiomers and their major metabolites in the rat by Mifsud, J., Millership, J.S., Collier, P.S., Morrow, R., Hamilton, J.T.G., McRoberts, W.C.

“…A chiral gas chromatographic assay has been developed for quantitative analysis of ethosuximide and its major metabolites in rat urine. The extraction…”
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Interference of mandelic acid with the determination of homatropine hydrobromide by second-order derivative spectroscopy by Millership, J S

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The use of polymeric solid phase extraction and HPLC analysis for the determination of ranitidine in routine plasma samples obtained from paediatric patients by Hare, L. G., Millership, J. S., Collier, P. S., McElnay, J. C., Carson, D. J., Shields, M. S.

“…A sensitive HPLC method for the determination of ranitidine in small‐volume (0.5 mL) paediatric plasma samples is described. Plasma samples were extracted…”
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Complexation and chromatographic studies involving water soluble calixarenes and nitrophenols by MILLERSHIP, J. S, MCKERVEY, M. A, RUSSELL, J. A

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Ratio spectra derivative spectrophotometry for the determination of furosemide and spironolactone in a capsule formulation by Millership, J.S., Parker, C., Donnelly, D.

“…The determination of furosemide and spironolactone in a capsule formulation has been investigated using techniques such as Vierordt's method and derivative…”
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The metabolism of ethosuximide by MILLERSHIP, J. S, MIFSUD, J, COLLIER, P. S

“…The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the…”
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Effect of miconazole and clotrimazole on K+ release and inhibition of ergosterol biosynthesis in Trichophyton mentagrophytes and related ultrastructural observations by Scott, E M, Gorman, S P, Millership, J S, Wright, L R

“…Measurement of K+ ions in extracellular fluids was used to provide evidence of direct membrane damage induced by miconazole and clotrimazole in Trichophyton…”
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The relation between molecular connectivity and gas chromatographic retention data by Millership, J S, Woolfson, A D

“…The recently developed topological index, molecular connectivity (chi), has been correlated using multiple regression analysis with gas chromatographic…”
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Molecular connectivity and gas chromatographic retention parameters by Millership, J S, Woolfson, A D

“…The relation between gas chromatographic retention parameters and molecular connectivity has been investigated for several series of compounds including…”
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High-performance liquid chromatographic determination of chlorpromazine and its degradation products in pharmaceutical dosage forms: a stability-indicating assay by Chagonda, L F, Millership, J S

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The determination of chlorpromazine, related impurities and degradation products in pharmaceutical dosage forms by Chagonda, L F, Millership, J S

“…The literature relating to the determination of chlorpromazine, related impurities and degradation products in pharmaceutical preparations is reviewed. Related…”
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