Search Results - "Miller, Rachel K"
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Using the Geriatric 5Ms to teach structural and social determinants of health
Published in Journal of the American Geriatrics Society (JAGS) (01-12-2023)Get full text
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Lung epithelial branching program antagonizes alveolar differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2013)“…Mammalian organs, including the lung and kidney, often adopt a branched structure to achieve high efficiency and capacity of their physiological functions…”
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Modeling congenital kidney diseases in Xenopus laevis
Published in Disease models & mechanisms (01-04-2019)“…Congenital anomalies of the kidney and urinary tract (CAKUT) occur in ∼1/500 live births and are a leading cause of pediatric kidney failure. With an average…”
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Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis
Published in PloS one (30-08-2019)“…Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and concentrate waste products into…”
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Effect of a Community‐Based Service Learning Experience in Geriatrics on Internal Medicine Residents and Community Participants
Published in Journal of the American Geriatrics Society (JAGS) (01-09-2017)“…Community‐based service learning (CBSL) provides an opportunity to teach internal medicine residents the social context of aging and clinical concepts. The…”
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An Interactive Ambulatory Nephrology Curriculum for Internal Medicine Interns: Design, Implementation, and Participant Feedback
Published in American journal of kidney diseases (01-09-2017)“…While diminishing nephrology fellow recruitment is a known issue, more work is needed to evaluate possible interventions to reverse this trend. We designed and…”
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Wnt to build a tube: Contributions of Wnt signaling to epithelial tubulogenesis
Published in Developmental dynamics (01-01-2010)“…Epithelial tubes are crucial to the function of organ systems including the cardiovascular system, pulmonary system, gastrointestinal tract, reproductive organ…”
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DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia
Published in Molecular biology of the cell (01-09-2014)“…p120-catenin (p120) modulates adherens junction (AJ) dynamics by controlling the stability of classical cadherins. Among all p120 isoforms, p120-3A and p120-1A…”
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Down's-syndrome-related kinase Dyrk1A modulates the p120-catenin-Kaiso trajectory of the Wnt signaling pathway
Published in Journal of cell science (01-02-2012)“…The Wnt pathways contribute to many processes in cancer and development, with β-catenin being a key canonical component. p120-catenin, which is structurally…”
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Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin
Published in Journal of cell science (15-05-2016)Get full text
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Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity
Published in PloS one (27-01-2014)“…Members of the plakophilin-catenin sub-family (Pkp-1, -2, and -3) facilitate the linkage of desmosome junctional components to each other (e.g. desmosomal…”
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Dynamin Binding Protein Is Required for Xenopus laevis Kidney Development
Published in Frontiers in physiology (26-02-2019)“…The adult human kidney contains over one million nephrons, with each nephron consisting of a tube containing segments that have specialized functions in…”
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The 5 Mʼs and More: A New Geriatric Medical Student Virtual Curriculum During the COVID‐19 Pandemic
Published in Journal of the American Geriatrics Society (JAGS) (01-11-2020)Get full text
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Strategies That Can Integrate Meaningful Geriatrics Content Into Medical School Curricula
Published in Academic medicine (01-12-2021)Get full text
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Rebooting Instrumental Activities of Daily Living for the 21st Century
Published in Annals of internal medicine (01-02-2022)“…Fessler et al discuss the reboot instrumental activities of daily living for the 21st century. From smart homes to web-based banking, technology has…”
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Home‐Based Medical Care: High‐Value Health Care During Coronavirus Disease 2019 and Beyond
Published in Journal of the American Geriatrics Society (JAGS) (01-02-2021)“…Ms. H is a 78‐year‐old woman with a history of congestive heart failure, chronic obstructive pulmonary disease, and recent stroke who was discharged 1 month…”
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Tissue-Specific Gene Inactivation in Xenopus laevis : Knockout of lhx1 in the Kidney with CRISPR/Cas9
Published in Genetics (Austin) (01-02-2018)“…Studying genes involved in organogenesis is often difficult because many of these genes are also essential for early development. The allotetraploid frog, , is…”
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Implementation of a geriatric assessment SmartPhrase: A multi-institutional pilot study
Published in Journal of the American Geriatrics Society (JAGS) (01-07-2024)Get full text
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A catenin of the plakophilin-subfamily, Pkp3, responds to canonical-Wnt pathway components and signals
Published in Biochemical and biophysical research communications (23-07-2021)“…Vertebrate beta-catenin plays a key role as a transducer of canonical-Wnt signals. We earlier reported that, similar to beta-catenin, the cytoplasmic signaling…”
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