Search Results - "Miller, Philip C."

MAPK Activation Predicts Poor Outcome and the MEK Inhibitor, Selumetinib, Reverses Antiestrogen Resistance in ER-Positive High-Grade Serous Ovarian Cancer by Hew, Karina E, Miller, Philip C, El-Ashry, Dorraya, Sun, Jun, Besser, Alexandra H, Ince, Tan A, Gu, Mengnan, Wei, Zhi, Zhang, Gao, Brafford, Patricia, Gao, Wei, Lu, Yiling, Mills, Gordon B, Slingerland, Joyce M, Simpkins, Fiona

“…Although 67% of high-grade serous ovarian cancers (HGSOC) express the estrogen receptor (ER), most fail antiestrogen therapy. Because MAPK activation is…”
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Conductive Poly(epichlorhydrin)–Polyaniline Dodecylbenzenesulfonate [PECH-PAni.DBSA] Rubber Blends Prepared in Solution by Bakhtiarian, Elaheh, Foot, Peter J.S., Tate, Philip C. Miller

“…Blends of poly(epichlorhydrin) elastomer [PECH] and polyaniline dodecylbenzenesulfonate [PAni.DBSA], with electrical conductivities up to 6.4×10−7 S cm−1, have…”
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Identification of Cancer-Associated Fibroblasts in Circulating Blood from Patients with Metastatic Breast Cancer by Ao, Zheng, Shah, Sanket H, Machlin, Leah M, Parajuli, Ritesh, Miller, Philip C, Rawal, Siddarth, Williams, Anthony J, Cote, Richard J, Lippman, Marc E, Datar, Ram H, El-Ashry, Dorraya

“…Metastasis is facilitated by cancer-associated fibroblasts (CAF) in the tumor microenvironment through mechanisms yet to be elucidated. In this study, we used…”
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A novel MAPK-microRNA signature is predictive of hormone-therapy resistance and poor outcome in ER-positive breast cancer by Miller, Philip C, Clarke, Jennifer, Koru-Sengul, Tulay, Brinkman, Joeli, El-Ashry, Dorraya

“…Hyperactivation of ERK1/2 MAPK (hMAPK) leads to loss of estrogen receptor (ER) expression and poor outcome in breast cancer. microRNAs (miRNA) play important…”
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Heterotypic clustering of circulating tumor cells and circulating cancer-associated fibroblasts facilitates breast cancer metastasis by Sharma, Utsav, Medina-Saenz, Kelsie, Miller, Philip C., Troness, Benjamin, Spartz, Angela, Sandoval-Leon, Ana, Parke, Deanna N., Seagroves, Tiffany N., Lippman, Marc E., El-Ashry, Dorraya

“…Background Cancer-associated fibroblasts (CAFs) are recruited to the tumor microenvironment (TME) and are critical drivers of breast cancer (BC) malignancy…”
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Paget’s disease of the nipple in a Her2-positive breast cancer xenograft model by Drews-Elger, Katherine, Sandoval-Leon, Ana Cristina, Ergonul, Ayse Burcu, Jegg, Anna M., Gomez-Fernandez, Carmen, Miller, Philip C., El-Ashry, Dorraya, Lippman, Marc E.

“…Purpose Paget’s disease (PD) of the breast is an uncommon disease of the nipple usually accompanied by an underlying carcinoma, often HER2 + , and accounting…”
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Abstract 3588: The spindle assembly checkpoint gene Bub1b is essential for the survival of some breast cancers by Koyuncu, Dilara, Goka, Erik T., Miller, Philip C., Lippman, Marc E.

“…As normal breast epithelium evolves towards malignancy, cells accumulate genomic changes that give them a replicative advantage while at the same time…”
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Transcriptome sequencing and annotation of the halophytic microalga Dunaliella salina by Hong, Ling, Liu, Jun-li, Midoun, Samira Z., Miller, Philip C.

“…The unicellular green alga Dunaliella salina is well adapted to salt stress and contains compounds (including β-carotene and vitamins) with potential…”
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Liquid biopsy: expanding the frontier of circulating biomarker discovery and validation in breast cancer by Miller, Philip C, El-Ashry, Dorraya, Lippman, Marc E

“…Liquid biopsies represent an attractive, minimally-invasive alternative to surgical sampling or complex imaging of breast cancer and breast cancer metastasis…”
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The Effects of Gamma Irradiation on Medical Grade Poly(methyl Methacrylate) by BARTON, Stephen J, FOOT, Peter J. S, MILLER TATE, Philip C, KISHI, Mariko, GHATORA, Baljit

“…Within developing countries the most cost-effective polymer used in the fabrication of rigid intraocular lenses (IOLs) is poly(methyl methacrylate) (PMMA), for…”
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Abstract 512: Knockdown of the spindle assembly checkpoint gene Bub1b results in increased cell death and cell cycle impairment in breast cancer by Koyuncu, Dilara, Goka, Erik T., Miller, Philip C., Lippman, Marc E.

“…Genomic instability is an enabling hallmark of cancer that provides cancer cells a replicative advantage. Accumulation of genomic aberrations can also…”
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盐生海藻杜氏盐藻的转录组测序以及注释 by Ling HONG;Jun-li LIU;Samira Z. MIDOUN;Philip C. MILLER

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Abstract 5325: Co-culture induced EMT in breast tumor cells is mediated through MAPK signaling and microRNA regulation by Miller, Philip C., Shah, Sanket, Lairet, Stephania, Steinberg, Alana, Heyn, Alexandra, Benito, Daniel, El-Ashry, Dorraya

“…Understanding how components of the microenvironment cooperate with tumor cells to facilitate tumor progression, metastasis, and clinical outcome is an…”
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MAPK activation predicts poor outcome and the MEK inhibitor, selumetinib, reverses antiestrogen resistance in high grade serous ovarian cancer by Hew, Karina E., Miller, Philip C., El-Ashry, Dorraya, Sun, Jun, Besser, Alexandra H., Ince, Tan A., Gu, Mengnan, Wei, Zhi, Zhang, Guo, Brafford, Patricia, Gao, W., Lu, Yiling, Mills, Gordon B., Slingerland, Joyce M., Simpkins, Fiona

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Abstract 3171: Hyperactive MAPK dysregulation of microRNAs contributes to the ER-negative phenotype in breast cancer by Philip, Miller C., Lairet, Stephania, Clarke, Jennifer, Richer, Jennifer, El-Ashry, Dorraya

“…We have previously shown that hyperactive MAPK (hMAPK) signaling in breast cancer results in repression of estrogen receptor (ER) expression and regulates…”
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Abstract 3946: Investigation of a hyperactive MAPK microRNA expression profile reveals potential role for microRNAs in the generation and maintenance of ER- phenotype in breast cancer by Miller, Philip C., Clarke, Jennifer, Koru-Sengal, Tulay, Brinkman, Joeli, El-Ashry, Dorraya

“…microRNAs (miRNAs) are small RNAs around 22 nucleotides in length that function as important regulators of cell and tissue specific gene regulation, and have…”
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Water Relations of Selected Species of Chaparral and Coastal Sage Communities by Poole, Dennis K., Miller, Philip C.

“…Water potentials, leaf resistances to water loss, and relative saturation deficits of selected shrub species of chaparral and coastal sage communities were…”
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The contribution of MicroRNAs in the biology of the ER-negative phenotype established by hyperactive ERK1/2 MAPK signaling in breast cancer by Miller, Philip C

“…ER-positive primary breast cancers can often be successfully treated with surgery followed by adjuvant anti-estrogen therapies. ER-negative breast cancers do…”
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Soil moisture relations in the southern California chaparral by Ng, Edward, Miller, Philip C.

“…Contrary to previous studies of vegetation cover and environment, soil moisture was greater on a south-facing slope than on the opposite north-facing slope in…”
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A home-based pain management and rehabilitation programme: an evaluation by Corey, David T, Etlin, David, Miller, Philip C

“…We report on a comprehensive and intensive cognitive-behavioural treatment programme which is conducted by behavioural therapists working primarily in…”
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