Search Results - "Miller, Peter G. G"

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML by Puram, Rishi V., Kowalczyk, Monika S., de Boer, Carl G., Schneider, Rebekka K., Miller, Peter G., McConkey, Marie, Tothova, Zuzana, Tejero, Héctor, Heckl, Dirk, Järås, Marcus, Chen, Michelle C., Li, Hubo, Tamayo, Alfred, Cowley, Glenn S., Rozenblatt-Rosen, Orit, Al-Shahrour, Fatima, Regev, Aviv, Ebert, Benjamin L.

“…Leukemia stem cells (LSCs) have the capacity to self-renew and propagate disease upon serial transplantation in animal models, and elimination of this cell…”
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PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells by Kahn, Josephine D., Miller, Peter G., Silver, Alexander J., Sellar, Rob S., Bhatt, Shruti, Gibson, Christopher, McConkey, Marie, Adams, Dylan, Mar, Brenton, Mertins, Philipp, Fereshetian, Shaunt, Krug, Karsten, Zhu, Haoling, Letai, Anthony, Carr, Steven A., Doench, John, Jaiswal, Siddhartha, Ebert, Benjamin L.

“…Truncating mutations in the terminal exon of protein phosphatase Mg2+/Mn2+ 1D (PPM1D) have been identified in clonal hematopoiesis and myeloid neoplasms, with…”
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An improved index for diagnosis and mortality prediction in malignancy-associated hemophagocytic lymphohistiocytosis by Zoref-Lorenz, Adi, Murakami, Jun, Hofstetter, Liron, Iyer, Swaminathan, Alotaibi, Ahmad S., Mohamed, Shehab Fareed, Miller, Peter G., Guber, Elad, Weinstein, Shiri, Yacobovich, Joanne, Nikiforow, Sarah, Ebert, Benjamin L., Lane, Adam, Pasvolsky, Oren, Raanani, Pia, Nagler, Arnon, Berliner, Nancy, Daver, Naval, Ellis, Martin, Jordan, Michael B.

“…Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening inflammatory syndrome that may complicate hematologic malignancies (HMs). The appropriateness of…”
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TET2-mutant clonal hematopoiesis and risk of gout by Agrawal, Mridul, Niroula, Abhishek, Cunin, Pierre, McConkey, Marie, Shkolnik, Veronica, Kim, Peter G., Wong, Waihay J., Weeks, Lachelle D., Lin, Amy E., Miller, Peter G., Gibson, Christopher J., Sekar, Aswin, Schaefer, Inga-Marie, Neuberg, Donna, Stone, Richard M., Bick, Alexander G., Uddin, Md Mesbah, Griffin, Gabriel K., Jaiswal, Siddhartha, Natarajan, Pradeep, Nigrovic, Peter A., Rao, Deepak A., Ebert, Benjamin L.

“…Gout is a common inflammatory arthritis caused by precipitation of monosodium urate (MSU) crystals in individuals with hyperuricemia. Acute flares are…”
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A historical overview of legislated alcohol policy in the Northern Territory of Australia: 1979-2021 by Clifford, Sarah, Smith, James A, Livingston, Michael, Wright, Cassandra J C, Griffiths, Kalinda E, Miller, Peter G

“…The Northern Territory (NT) has the highest levels of alcohol consumption and harms in Australia. Since the creation of the NT Liquor Act 1978, which came into…”
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Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs by Sperling, Adam S., Burgess, Michael, Keshishian, Hasmik, Gasser, Jessica A., Bhatt, Shruti, Jan, Max, Słabicki, Mikołaj, Sellar, Rob S., Fink, Emma C., Miller, Peter G., Liddicoat, Brian J., Sievers, Quinlan L., Sharma, Rohan, Adams, Dylan N., Olesinski, Elyse A., Fulciniti, Mariateresa, Udeshi, Namrata D., Kuhn, Eric, Letai, Anthony, Munshi, Nikhil C., Carr, Steven A., Ebert, Benjamin L.

“…Pharmacologic agents that modulate ubiquitin ligase activity to induce protein degradation are a major new class of therapeutic agents, active in a number of…”
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Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells by Sellar, Rob S, Sperling, Adam S, Słabicki, Mikołaj, Gasser, Jessica A, McConkey, Marie E, Donovan, Katherine A, Mageed, Nada, Adams, Dylan N, Zou, Charles, Miller, Peter G, Dutta, Ravi K, Boettcher, Steffen, Lin, Amy E, Sandoval, Brittany, Quevedo Barrios, Vanessa A, Kovalcik, Veronica, Koeppel, Jonas, Henderson, Elizabeth K, Fink, Emma C, Yang, Lu, Chan, Anthony, Pokharel, Sheela Pangeni, Bergstrom, Erik J, Burt, Rajan, Udeshi, Namrata D, Carr, Steven A, Fischer, Eric S, Chen, Chun-Wei, Ebert, Benjamin L

“…Targeted protein degradation is a rapidly advancing and expanding therapeutic approach. Drugs that degrade GSPT1 via the CRL4CRBN ubiquitin ligase are a new…”
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The revolving door between government and the alcohol, food and gambling industries in Australia by Robertson, Narelle M, Sacks, Gary, Miller, Peter G

“…To explore the incidence of the 'revolving door' phenomenon, whereby individuals move between positions in government and positions in the Australian alcohol,…”
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Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state by Miller, Peter G., Sathappa, Murugappan, Moroco, Jamie A., Jiang, Wei, Qian, Yue, Iqbal, Sumaiya, Guo, Qi, Giacomelli, Andrew O., Shaw, Subrata, Vernier, Camille, Bajrami, Besnik, Yang, Xiaoping, Raffier, Cerise, Sperling, Adam S., Gibson, Christopher J., Kahn, Josephine, Jin, Cyrus, Ranaghan, Matthew, Caliman, Alisha, Brousseau, Merissa, Fischer, Eric S., Lintner, Robert, Piccioni, Federica, Campbell, Arthur J., Root, David E., Garvie, Colin W., Ebert, Benjamin L.

“…PPM1D encodes a serine/threonine phosphatase that regulates numerous pathways including the DNA damage response and p53. Activating mutations and amplification…”
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Awareness and correlates of short‐term and long‐term consequences of alcohol use among Australian drinkers by Coomber, Kerri, Mayshak, Richelle, Curtis, Ashlee, Miller, Peter G.

“…To investigate awareness of short‐term and long‐term consequences of alcohol use among a sample of Australian adult drinkers. Demographic correlates of the…”
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Alcohol Accessibility and Family Violence-related Ambulance Attendances by Scott, Debbie, Ogeil, Rowan P., Maoyeri, Foruhar, Heilbronn, Cherie, Coomber, Kerri, Smith, Karen, Miller, Peter G., Lubman, Dan I.

“…There is substantial evidence supporting the association between alcohol license density and violent crime. However, the impact of different types of alcohol…”
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In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling by Miller, Peter G., Al-Shahrour, Fatima, Hartwell, Kimberly A., Chu, Lisa P., Järås, Marcus, Puram, Rishi V., Puissant, Alexandre, Callahan, Kevin P., Ashton, John, McConkey, Marie E., Poveromo, Luke P., Cowley, Glenn S., Kharas, Michael G., Labelle, Myriam, Shterental, Sebastian, Fujisaki, Joji, Silberstein, Lev, Alexe, Gabriela, Al-Hajj, Muhammad A., Shelton, Christopher A., Armstrong, Scott A., Root, David E., Scadden, David T., Hynes, Richard O., Mukherjee, Siddhartha, Stegmaier, Kimberly, Jordan, Craig T., Ebert, Benjamin L.

“…We used an in vivo small hairpin RNA (shRNA) screening approach to identify genes that are essential for MLL-AF9 acute myeloid leukemia (AML). We found that…”
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Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia by Järås, Marcus, Miller, Peter G, Chu, Lisa P, Puram, Rishi V, Fink, Emma C, Schneider, Rebekka K, Al-Shahrour, Fatima, Peña, Pablo, Breyfogle, L Jordan, Hartwell, Kimberly A, McConkey, Marie E, Cowley, Glenn S, Root, David E, Kharas, Michael G, Mullally, Ann, Ebert, Benjamin L

“…Despite extensive insights into the underlying genetics and biology of acute myeloid leukemia (AML), overall survival remains poor and new therapies are…”
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Unconvincing and ineffective: Young adult responses to current Australian alcohol product warnings by Kerri Coomber, Alexa Hayley, Peter G. Miller

“…Objective Public health literature suggests that alcohol warnings on products could be utilised to effectively communicate the risks of alcohol consumption…”
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Queensland Alcohol-related violence and Night Time Economy Monitoring project (QUANTEM): a study protocol by Miller, Peter G, Ferris, Jason, Coomber, Kerri, Zahnow, Renee, Carah, Nicholas, Jiang, Heng, Kypri, Kypros, Chikritzhs, Tanya, Clough, Alan, Livingston, Michael, de Andrade, Dominique, Room, Robin, Callinan, Sarah, Curtis, Ashlee, Mayshak, Richelle, Droste, Nicolas, Lloyd, Belinda, Matthews, Sharon, Taylor, Nicholas, Crane, Meredythe, Thorn, Michael, Najman, Jake

“…Alcohol-related harm is a substantial burden on the community in Australia and internationally, particularly harm related to risky drinking practices of young…”
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A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade by Miller, Peter G, Sperling, Adam S, Gibson, Christopher J, Pozdnyakova, Olga, Wong, Waihay J, Manos, Michael P, Buchbinder, Elizabeth I, Hodi, F Stephen, Ebert, Benjamin L, Davids, Matthew S

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Side-loading prevalence and intoxication in the night-time economy by Cameron, Michael P., Miller, Peter G., Roskruge, Matthew

“…•A substantial minority of the ambient population in the night-time economy had engaged in side-loading.•Unlike pre-drinking, side-loading was not…”
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Gene Sets Identified with Oncogene Cooperativity Analysis Regulate In Vivo Growth and Survival of Leukemia Stem Cells by Ashton, John M., Balys, Marlene, Neering, Sarah J., Hassane, Duane C., Cowley, Glenn, Root, David E., Miller, Peter G., Ebert, Benjamin L., McMurray, Helene R., Land, Hartmut, Jordan, Craig T.

“…Leukemia stem cells (LSCs) represent a biologically distinct subpopulation of myeloid leukemias, with reduced cell cycle activity and increased resistance to…”
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Experiences of trauma and alcohol and other drug use by domestic, family, and sexual violence offenders: A review of 6 months of sentencing remarks from the supreme court of the Northern territory, Australia by Clifford, Sarah, Wright, Cassandra JC, Livingston, Michael, Smith, James A, Griffiths, Kalinda E, Miller, Peter G

“…The Northern Territory (NT) has the highest rates of domestic, family and sexual violence (DFSV) in Australia. Although we know that alcohol and other drug…”
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Neurocognitive functioning among people accessing an addiction neuropsychology clinic with and without a history of offending behaviour by Curtis, Ashlee, Gooden, James R., Cox, Catherine A., Harries, Travis, Peterson, Vanessa, Enticott, Peter G., Sanfilippo, Paul G., Miller, Peter G., Lubman, Dan I., Manning, Victoria

“…Effectiveness of interventions for violent behaviour may be undermined by the presence of neurocognitive impairment, which is known to be common among alcohol…”
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