Search Results - "Miller, Nathaniel L."

Raman Spectroscopy for Rapid Evaluation of Surgical Margins during Breast Cancer Lumpectomy by Zúñiga, Willie C., Jones, Veronica, Anderson, Sarah M., Echevarria, Alex, Miller, Nathaniel L., Stashko, Connor, Schmolze, Daniel, Cha, Philip D., Kothari, Ragini, Fong, Yuman, Storrie-Lombardi, Michael C.

“…Failure to precisely distinguish malignant from healthy tissue has severe implications for breast cancer surgical outcomes. Clinical prognoses depend on…”
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Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain by Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram

“…The Omicron variant features enhanced transmissibility and antibody escape. Here, we describe the Omicron receptor-binding domain (RBD) mutational landscape…”
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Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies by Miller, Nathaniel L., Raman, Rahul, Clark, Thomas, Sasisekharan, Ram

“…The dynamic interplay between virus and host plays out across many interacting surfaces as virus and host evolve continually in response to one another. In…”
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Conserved topology of virus glycoepitopes presents novel targets for repurposing HIV antibody 2G12 by Miller, Nathaniel L., Subramanian, Vidya, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram

“…Complex glycans decorate viral surface proteins and play a critical role in virus–host interactions. Viral surface glycans shield vulnerable protein epitopes…”
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An Antigenic Space Framework for Understanding Antibody Escape of SARS-CoV-2 Variants by Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram

“…The evolution of mutations in SARS-CoV-2 at antigenic sites that impact neutralizing antibody responses in humans poses a risk to immunity developed through…”
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Glycans in Virus-Host Interactions: A Structural Perspective by Miller, Nathaniel L, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram

“…Many interactions between microbes and their hosts are driven or influenced by glycans, whose heterogeneous and difficult to characterize structures have led…”
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Learned features of antibody-antigen binding affinity by Miller, Nathaniel L, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram

“…Defining predictors of antigen-binding affinity of antibodies is valuable for engineering therapeutic antibodies with high binding affinity to their targets…”
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