Search Results - "Miller, Martin"
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1
Race-Specific Interpretation of Spirometry
Published in Annals of the American Thoracic Society (01-10-2024)Get more information
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Comprehensive Benchmarking and Integration of Tumor Microenvironment Cell Estimation Methods
Published in Cancer research (Chicago, Ill.) (15-12-2019)“…Various computational approaches have been developed for estimating the relative abundance of different cell types in the tumor microenvironment (TME) using…”
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Emerging landscape of oncogenic signatures across human cancers
Published in Nature genetics (01-10-2013)“…Chris Sander and colleagues have extracted significant functional events from 12 tumor types. Tumors can be classified as being driven largely by either…”
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ERS/ATS technical standard on interpretive strategies for routine lung function tests
Published in The European respiratory journal (01-07-2022)“…Appropriate interpretation of pulmonary function tests (PFTs) involves the classification of observed values as within/outside the normal range based on a…”
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Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement
Published in American journal of respiratory and critical care medicine (15-10-2019)“…Spirometry is the most common pulmonary function test. It is widely used in the assessment of lung function to provide objective information used in the…”
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Ovarian tumors orchestrate distinct cellular compositions
Published in Immunity (Cambridge, Mass.) (08-06-2021)“…The determinants of T cell infiltration in tumors remain largely unknown. In a recent issue of Cancer Cell, Hornburg et al. use single-cell RNA sequencing to…”
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Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Published in Science (American Association for the Advancement of Science) (03-04-2015)“…Immune checkpoint inhibitors, which unleash a patient's own T cells to kill tumors, are revolutionizing cancer treatment. To unravel the genomic determinants…”
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Lack of detectable neoantigen depletion signals in the untreated cancer genome
Published in Nature genetics (01-12-2019)“…Somatic mutations can result in the formation of neoantigens, immunogenic peptides that are presented on the tumor cell surface by HLA molecules. These…”
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Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
Published in Cell (24-08-2017)“…We present an exceptional case of a patient with high-grade serous ovarian cancer, treated with multiple chemotherapy regimens, who exhibited regression of…”
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Structural and physiological age-associated changes in aging lungs
Published in Seminars in respiratory and critical care medicine (01-10-2010)“…The tissues of the lungs undergo changes with age that lead to an increase in alveolar size without any destruction of alveolar walls. This lowers the alveolar…”
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Increasing Divergence in Spirometry Recommendations
Published in Chest (01-12-2023)Get full text
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KinomeXplorer: an integrated platform for kinome biology studies
Published in Nature methods (01-06-2014)Get full text
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UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
Published in Cell (19-09-2019)“…Although clonal neo-antigen burden is associated with improved response to immune therapy, the functional basis for this remains unclear. Here we study this…”
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Mitochondrial DNA copy number variation across human cancers
Published in eLife (22-02-2016)“…Mutations, deletions, and changes in copy number of mitochondrial DNA (mtDNA), are observed throughout cancers. Here, we survey mtDNA copy number variation…”
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Interpreting Lung Function Data Using 80% Predicted and Fixed Thresholds Misclassifies More Than 20% of Patients
Published in Chest (2011)“…Background Differences in COPD classification have been shown in population data sets when using fifth percentiles as the lower limit of normal (LLN) vs the…”
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Chronic obstructive pulmonary disease: missed diagnosis versus misdiagnosis
Published in BMJ (Online) (01-07-2015)Get full text
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Does the use of per cent of predicted have any evidence base?
Published in The European respiratory journal (01-02-2015)“…Over 20years ago there was a move to require an evidence base for the practice of medicine [1]. It is easy to understand that any new treatment or management…”
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Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Published in Science signaling (12-01-2010)“…Eukaryotic cells replicate by a complex series of evolutionarily conserved events that are tightly regulated at defined stages of the cell division cycle…”
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FEV1:FVC Thresholds for Defining Chronic Obstructive Pulmonary Disease
Published in JAMA : the journal of the American Medical Association (22-10-2019)Get full text
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Choosing and using lung function prediction equations
Published in The European respiratory journal (01-12-2016)Get full text
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