Search Results - "Miller, Lloyd S."

The role of the transcription factor CREB in immune function by Wen, Andy Y, Sakamoto, Kathleen M, Miller, Lloyd S

“…CREB is a transcription factor that regulates diverse cellular responses, including proliferation, survival, and differentiation. CREB is induced by a variety…”
Get full text

Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms by Miller, Lloyd S, Fowler, Vance G, Shukla, Sanjay K, Rose, Warren E, Proctor, Richard A

“…ABSTRACT Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in both hospital and community settings, especially with the…”
Get full text

Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis by Patrick, Garrett J., Archer, Nathan K., Miller, Lloyd S.

“…Atopic dermatitis (AD) is a common, chronic, inflammatory skin condition characterized by recurrent and pruritic skin eruptions. Multiple factors contribute to…”
Get full text

Host–pathogen interactions between the skin and Staphylococcus aureus by Krishna, Sheila, Miller, Lloyd S

“…Highlights ► S. aureus is a major cause of skin and soft tissue infections. ► Commensal organisms and antimicrobial peptides protect against S. aureus skin…”
Get full text

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis by Herster, Franziska, Bittner, Zsofia, Archer, Nathan K., Dickhöfer, Sabine, Eisel, David, Eigenbrod, Tatjana, Knorpp, Thomas, Schneiderhan-Marra, Nicole, Löffler, Markus W., Kalbacher, Hubert, Vierbuchen, Tim, Heine, Holger, Miller, Lloyd S., Hartl, Dominik, Freund, Lukas, Schäkel, Knut, Heister, Martin, Ghoreschi, Kamran, Weber, Alexander N. R.

“…Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high levels of the antimicrobial peptide, LL37. LL37 in complex with…”
Get full text

A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome by Munoz-Planillo, Raul, Franchi, Luigi, Miller, Lloyd S, Nunez, Gabriel

“…The mechanism by which bacterial pathogens activate caspase-1 via Nlrp3 remains poorly understood. In this study, we show that the ability of Staphylococcus…”
Get full text

Leukotriene B4-Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation by Oyoshi, Michiko K., He, Rui, Li, Yitang, Mondal, Subhanjan, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David M., Luo, Hongbo R., Luster, Andrew D., Cho, John S., Miller, Lloyd S., Larson, Allison, Murphy, George F., Geha, Raif S.

“…Scratching triggers skin flares in atopic dermatitis. We demonstrate that scratching of human skin and tape stripping of mouse skin cause neutrophil influx. In…”
Get full text

Association between prurigo nodularis and malignancy in middle-aged adults by Larson, Valerie A., Tang, Olive, Stander, Sonja, Miller, Lloyd S., Kang, Sewon, Kwatra, Shawn G.

Get full text

dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration by Nelson, Amanda M., Reddy, Sashank K., Ratliff, Tabetha S., Hossain, M. Zulfiquer, Katseff, Adiya S., Zhu, Amadeus S., Chang, Emily, Resnik, Sydney R., Page, Carly, Kim, Dongwon, Whittam, Alexander J., Miller, Lloyd S., Garza, Luis A.

“…Regeneration of skin and hair follicles after wounding—a process known as wound-induced hair neogenesis (WIHN)—is a rare example of adult organogenesis in…”
Get full text

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice by Cho, John S, Guo, Yi, Ramos, Romela Irene, Hebroni, Frank, Plaisier, Seema B, Xuan, Caiyun, Granick, Jennifer L, Matsushima, Hironori, Takashima, Akira, Iwakura, Yoichiro, Cheung, Ambrose L, Cheng, Genhong, Lee, Delphine J, Simon, Scott I, Miller, Lloyd S

“…Neutrophil abscess formation is critical in innate immunity against many pathogens. Here, the mechanism of neutrophil abscess formation was investigated using…”
Get full text

A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings by Bernthal, Nicholas M, Stavrakis, Alexandra I, Billi, Fabrizio, Cho, John S, Kremen, Thomas J, Simon, Scott I, Cheung, Ambrose L, Finerman, Gerald A, Lieberman, Jay R, Adams, John S, Miller, Lloyd S

“…Post-arthroplasty infections represent a devastating complication of total joint replacement surgery, resulting in multiple reoperations, prolonged antibiotic…”
Get full text

Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3 by Kim, Dongwon, Chen, Ruosi, Sheu, Mary, Kim, Noori, Kim, Sooah, Islam, Nasif, Wier, Eric M., Wang, Gaofeng, Li, Ang, Park, Angela, Son, Wooyang, Evans, Benjamin, Yu, Victoria, Prizmic, Vicky P., Oh, Eugene, Wang, Zixiao, Yu, Jianshi, Huang, Weiliang, Archer, Nathan K., Hu, Zhiqi, Clemetson, Nashay, Nelson, Amanda M., Chien, Anna, Okoye, Ginette A., Miller, Lloyd S., Ghiaur, Gabriel, Kang, Sewon, Jones, Jace W., Kane, Maureen A., Garza, Luis A.

“…How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair…”
Get full text

Interleukin-17A (IL-17A) and IL-17F Are Critical for Antimicrobial Peptide Production and Clearance of Staphylococcus aureus Nasal Colonization by Archer, Nathan K, Adappa, Nithin D, Palmer, James N, Cohen, Noam A, Harro, Jan M, Lee, Steven K, Miller, Lloyd S, Shirtliff, Mark E

“…Approximately 20% of the population is persistently colonized by Staphylococcus aureus in the nares. Th17-like immune responses mediated by the interleukin-17…”
Get full text

Broad-Spectrum Antimicrobial and Biofilm-Disrupting Hydrogels: Stereocomplex-Driven Supramolecular Assemblies by Li, Yan, Fukushima, Kazuki, Coady, Daniel J., Engler, Amanda C., Liu, Shaoqiong, Huang, Yuan, Cho, John S., Guo, Yi, Miller, Lloyd S., Tan, Jeremy P. K., Ee, Pui Lai Rachel, Fan, Weimin, Yang, Yi Yan, Hedrick, James L.

“…Fighting the resistance: Biodegradable and injectable/moldable hydrogels with hierarchical nanostructures (see picture) were made with broad‐spectrum…”
Get full text

IL-22 derived from γδ T cells restricts Staphylococcus aureus infection of mechanically injured skin by Malhotra, Nidhi, PhD, Yoon, Juhan, PhD, Leyva-Castillo, Juan Manuel, PhD, Galand, Claire, PhD, Archer, Nathan, MD, PhD, Miller, Lloyd S., MD, Geha, Raif S., MD

“…Background Staphylococcus aureus is an opportunistic pathogen that colonizes the skin of patients with atopic dermatitis (AD) and aggravates their disease…”
Get full text

Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice by Ortines, Roger V, Liu, Haiyun, Cheng, Lily I, Cohen, Taylor S, Lawlor, Heather, Gami, Abhishek, Wang, Yu, Dillen, Carly A, Archer, Nathan K, Miller, Robert J, Ashbaugh, Alyssa G, Pinsker, Bret L, Marchitto, Mark C, Tkaczyk, Christine, Stover, C Kendall, Sellman, Bret R, Miller, Lloyd S

“…wound infections delay healing and result in invasive complications such as osteomyelitis, especially in the setting of diabetic foot ulcers. In preclinical…”
Get full text

Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection by Oliva Chávez, Adela S., Wang, Xiaowei, Marnin, Liron, Archer, Nathan K., Hammond, Holly L., Carroll, Erin E. McClure, Shaw, Dana K., Tully, Brenden G., Buskirk, Amanda D., Ford, Shelby L., Butler, L. Rainer, Shahi, Preeti, Morozova, Kateryna, Clement, Cristina C., Lawres, Lauren, Neal, Anya J. O’, Mamoun, Choukri Ben, Mason, Kathleen L., Hobbs, Brandi E., Scoles, Glen A., Barry, Eileen M., Sonenshine, Daniel E., Pal, Utpal, Valenzuela, Jesus G., Sztein, Marcelo B., Pasetti, Marcela F., Levin, Michael L., Kotsyfakis, Michail, Jay, Steven M., Huntley, Jason F., Miller, Lloyd S., Santambrogio, Laura, Pedra, Joao H. F.

“…Extracellular vesicles are thought to facilitate pathogen transmission from arthropods to humans and other animals. Here, we reveal that pathogen spreading…”
Get full text

Comparative intravital imaging of human and rodent malaria sporozoites reveals the skin is not a species‐specific barrier by Hopp, Christine S, Kanatani, Sachie, Archer, Nathan K, Miller, Robert J, Liu, Haiyun, Chiou, Kevin K, Miller, Lloyd S, Sinnis, Photini

“…Malaria infection starts with the injection of Plasmodium sporozoites into the host’s skin. Sporozoites are motile and move in the skin to find and enter blood…”
Get full text

Vancomycin-Rifampin Combination Therapy Has Enhanced Efficacy against an Experimental Staphylococcus aureus Prosthetic Joint Infection by NISKA, Jared A, SHAHBAZIAN, Jonathan H, IRENE RAMOS, Romela, FRANCIS, Kevin P, BERNTHAL, Nicholas M, MILLER, Lloyd S

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Mouse model of chronic post-arthroplasty infection: Noninvasive in vivo bioluminescence imaging to monitor bacterial burden for long-term study by Pribaz, Jonathan R., Bernthal, Nicholas M., Billi, Fabrizio, Cho, John S., Ramos, Romela Irene, Guo, Yi, Cheung, Ambrose L., Francis, Kevin P., Miller, Lloyd S.

“…Post‐arthroplasty infections are a devastating problem in orthopaedic surgery. While acute infections can be treated with a single stage washout and liner…”
Get full text