Search Results - "Miller, Lee E"
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Restoring sensorimotor function through intracortical interfaces: progress and looming challenges
Published in Nature reviews. Neuroscience (01-05-2014)“…Key Points Brain–machine interface (BMI) control of the kinematics of reaching has progressed dramatically, whereas BMI control of the hand and of the dynamics…”
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Neural Manifolds for the Control of Movement
Published in Neuron (Cambridge, Mass.) (07-06-2017)“…The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural…”
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A Neural Population Mechanism for Rapid Learning
Published in Neuron (Cambridge, Mass.) (21-11-2018)“…Long-term learning of language, mathematics, and motor skills likely requires cortical plasticity, but behavior often requires much faster changes, sometimes…”
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Long-term stability of cortical population dynamics underlying consistent behavior
Published in Nature neuroscience (01-02-2020)“…Animals readily execute learned behaviors in a consistent manner over long periods of time, and yet no equally stable neural correlate has been demonstrated…”
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Estimating the dimensionality of the manifold underlying multi-electrode neural recordings
Published in PLoS computational biology (01-11-2021)“…It is generally accepted that the number of neurons in a given brain area far exceeds the number of neurons needed to carry any specific function controlled by…”
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Cortical population activity within a preserved neural manifold underlies multiple motor behaviors
Published in Nature communications (12-10-2018)“…Populations of cortical neurons flexibly perform different functions; for the primary motor cortex (M1) this means a rich repertoire of motor behaviors. We…”
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Single reach plans in dorsal premotor cortex during a two-target task
Published in Nature communications (03-09-2018)“…In many situations, we are faced with multiple potential actions, but must wait for more information before knowing which to perform. Movement scientists have…”
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Responses of somatosensory area 2 neurons to actively and passively generated limb movements
Published in Journal of neurophysiology (01-03-2013)“…Control of reaching movements requires an accurate estimate of the state of the limb, yet sensory signals are inherently noisy, because of both noise at the…”
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Machine Learning for Neural Decoding
Published in eNeuro (01-07-2020)“…Despite rapid advances in machine learning tools, the majority of neural decoding approaches still use traditional methods. Modern machine learning tools,…”
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Area 2 of primary somatosensory cortex encodes kinematics of the whole arm
Published in eLife (23-01-2020)“…Proprioception, the sense of body position, movement, and associated forces, remains poorly understood, despite its critical role in movement. Most studies of…”
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De novo motor learning creates structure in neural activity that shapes adaptation
Published in Nature communications (14-05-2024)“…Animals can quickly adapt learned movements to external perturbations, and their existing motor repertoire likely influences their ease of adaptation…”
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Population coding of conditional probability distributions in dorsal premotor cortex
Published in Nature communications (03-05-2018)“…Our bodies and the environment constrain our movements. For example, when our arm is fully outstretched, we cannot extend it further. More generally, the…”
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Using adversarial networks to extend brain computer interface decoding accuracy over time
Published in eLife (23-08-2023)“…Existing intracortical brain computer interfaces (iBCIs) transform neural activity into control signals capable of restoring movement to persons with…”
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Brain-controlled muscle stimulation for the restoration of motor function
Published in Neurobiology of disease (01-11-2015)“…Abstract Loss of the ability to move, as a consequence of spinal cord injury or neuromuscular disorder, has devastating consequences for the paralyzed…”
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Small, correlated changes in synaptic connectivity may facilitate rapid motor learning
Published in Nature communications (02-09-2022)“…Animals rapidly adapt their movements to external perturbations, a process paralleled by changes in neural activity in the motor cortex. Experimental studies…”
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Fully implanted battery-free high power platform for chronic spinal and muscular functional electrical stimulation
Published in Nature communications (30-11-2023)“…Electrical stimulation of the neuromuscular system holds promise for both scientific and therapeutic biomedical applications. Supplying and maintaining the…”
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Stoney vs. Histed: Quantifying the spatial effects of intracortical microstimulation
Published in Brain stimulation (01-01-2022)“…Intracortical microstimulation (ICMS) is used to map neural circuits and restore lost sensory modalities such as vision, hearing, and somatosensation. The…”
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Accurate decoding of reaching movements from field potentials in the absence of spikes
Published in Journal of neural engineering (01-08-2012)“…The recent explosion of interest in brain-machine interfaces (BMIs) has spurred research into choosing the optimal input signal source for a desired…”
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Linear-nonlinear-time-warp-poisson models of neural activity
Published in Journal of computational neuroscience (01-12-2018)“…Prominent models of spike trains assume only one source of variability – stochastic (Poisson) spiking – when stimuli and behavior are fixed. However, spike…”
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Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner
Published in eLife (15-08-2022)“…The spiking activity of populations of cortical neurons is well described by the dynamics of a small number of population-wide covariance patterns, whose…”
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