Search Results - "Miller, Joshua R"
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Label-Free Microfluidic Manipulation of Particles and Cells in Magnetic Liquids
Published in Advanced functional materials (14-06-2016)“…Manipulating particles and cells in magnetic liquids through “negative magnetophoresis” is a new research field. It has resulted in label‐free and low‐cost…”
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Spectroscopic analysis of the mammalian enzyme cysteine dioxygenase
Published in Methods in enzymology (2023)“…l-Cysteine (Cys) is an essential building block for the synthesis of new proteins and serves as a precursor for several biologically important…”
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Kinetic and Spectroscopic Investigation of the Y157F and C93G/Y157F Variants of Cysteine Dioxygenase: Dissecting the Roles of the Second-Sphere Residues C93 and Y157
Published in Biochemistry (Easton) (02-07-2024)“…In mammals, l-cysteine (Cys) homeostasis is maintained by the mononuclear nonheme iron enzyme cysteine dioxygenase (CDO), which oxidizes Cys to cysteine…”
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Spectroscopic and Computational Comparisons of Thiolate-Ligated Ferric Nonheme Complexes to Cysteine Dioxygenase: Second-Sphere Effects on Substrate (Analogue) Positioning
Published in Inorganic chemistry (16-12-2019)“…Parallel spectroscopic and computational studies of iron(III) cysteine dioxygenase (CDO) and synthetic models are presented. The synthetic complexes utilize…”
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Electronic structures and spectroscopic signatures of diiron intermediates generated by O 2 activation of nonheme iron(II)-thiolate complexes
Published in Dalton transactions : an international journal of inorganic chemistry (19-10-2021)“…The activation of O at thiolate-ligated iron(II) sites is essential to the function of numerous metalloenzymes and synthetic catalysts. Iron-thiolate bonds in…”
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Journal Article -
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Spectroscopic and Kinetic Analysis of Mammalian Cysteine Dioxygenase
Published 01-01-2023“…L-Cysteine (Cys) is a semi-essential amino acid that plays a variety of roles in mammals. Cys serves as a monomer in the synthesis of new proteins and is a…”
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Dissertation