Search Results - "Miller, Dawson"
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Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model
Published in Antimicrobial agents and chemotherapy (15-11-2023)“…BTZ-043, a suicide inhibitor of the cell wall synthesis decaprenylphosphoryl-beta-D-ribose 2' epimerase, is under clinical development as a potential new…”
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Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
Published in Nature communications (11-06-2024)“…As spaceflight becomes more common with commercial crews, blood-based measures of crew health can guide both astronaut biomedicine and countermeasures. By…”
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A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy
Published in EMBO molecular medicine (10-07-2023)“…Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues…”
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Author Correction: A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva
Published in Scientific reports (07-02-2024)Get full text
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A multiplexed, paired-pooled droplet digital PCR assay for detection of SARS-CoV-2 in saliva
Published in Scientific reports (22-02-2023)“…In response to the SARS-CoV-2 pandemic, we developed a m ulti p lexed, p aired- p ool droplet digital P CR (MP4) screening assay. Key features of our assay are…”
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Biomolecular condensates create phospholipid-enriched microenvironments
Published in Nature chemical biology (01-03-2024)“…Proteins and RNA can phase separate from the aqueous cellular environment to form subcellular compartments called condensates. This process results in a…”
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Two‐pore channel 2 is required for soluble adenylyl cyclase‐dependent regulation of melanosomal pH and melanin synthesis
Published in Pigment cell and melanoma research (01-09-2024)“…Melanosomal pH is important for the synthesis of melanin as the rate‐limiting enzyme, tyrosinase, is very pH‐sensitive. The soluble adenylyl cyclase (sAC)…”
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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Published in Nature (London) (29-08-2024)“…Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming…”
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Seeing Curvature on Specular Surfaces
Published in The American mathematical monthly (21-04-2018)“…Reflections on a specular surface distort their surrounding environments in ways that give visual clues about the surface's principal and Gaussian curvatures…”
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Teachers’ Facilitation of 21st Century Skills With Texas Rural High School Students: An Explanatory Sequential Mixed Methods Study
Published 01-01-2023“…America’s education system does not meet the needs of 21st century students who live and will work in a Knowledge Age economy. Contextual forces outside the…”
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Dissertation