Search Results - "Miller, Daniel G."

Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy by Lemmers, Richard J.L.F, van der Vliet, Patrick J, Klooster, Rinse, Sacconi, Sabrina, Camaño, Pilar, Dauwerse, Johannes G, Snider, Lauren, Straasheijm, Kirsten R, Jan van Ommen, Gert, Padberg, George W, Miller, Daniel G, Tapscott, Stephen J, Tawil, Rabi, Frants, Rune R, van der Maarel, Silvère M

“…Facioscapulohumeral muscular dystrophy (FSHD) is a common form of muscular dystrophy in adults that is foremost characterized by progressive wasting of muscles…”
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GGC Repeat Expansion and Exon 1 Methylation of XYLT1 Is a Common Pathogenic Variant in Baratela-Scott Syndrome by LaCroix, Amy J., Stabley, Deborah, Sahraoui, Rebecca, Adam, Margaret P., Mehaffey, Michele, Kernan, Kelly, Myers, Candace T., Fagerstrom, Carrie, Anadiotis, George, Akkari, Yassmine M., Robbins, Katherine M., Gripp, Karen W., Baratela, Wagner A.R., Bober, Michael B., Duker, Angela L., Doherty, Dan, Dempsey, Jennifer C., Miller, Daniel G., Kircher, Martin, Bamshad, Michael J., Nickerson, Deborah A., Mefford, Heather C., Sol-Church, Katia

“…Baratela-Scott syndrome (BSS) is a rare, autosomal-recessive disorder characterized by short stature, facial dysmorphisms, developmental delay, and skeletal…”
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AAV Vector Integration Sites in Mouse Hepatocellular Carcinoma by Donsante, Anthony, Miller, Daniel G, Li, Yi, Vogler, Carole, Brunt, Elizabeth M, Russell, David W, Sands, Mark S

“…Adeno-associated viruses (AAV) are promising gene therapy vectors that have little or no acute toxicity. We show that normal mice and mice with…”
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Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene by Snider, Lauren, Geng, Linda N, Lemmers, Richard J L F, Kyba, Michael, Ware, Carol B, Nelson, Angelique M, Tawil, Rabi, Filippova, Galina N, van der Maarel, Silvère M, Tapscott, Stephen J, Miller, Daniel G

“…Each unit of the D4Z4 macrosatellite repeat contains a retrotransposed gene encoding the DUX4 double-homeobox transcription factor. Facioscapulohumeral…”
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Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele by Haynes, Premi, Bomsztyk, Karol, Miller, Daniel G

“…Facioscapulohumeral muscular dystrophy 1 (FSHD1) has an autosomal dominant pattern of inheritance and primarily affects skeletal muscle. The genetic cause of…”
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A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles by Caron, Leslie, Kher, Devaki, Lee, Kian Leong, McKernan, Robert, Dumevska, Biljana, Hidalgo, Alejandro, Li, Jia, Yang, Henry, Main, Heather, Ferri, Giulia, Petek, Lisa M, Poellinger, Lorenz, Miller, Daniel G, Gabellini, Davide, Schmidt, Uli

“…: Facioscapulohumeral muscular dystrophy (FSHD) represents a major unmet clinical need arising from the progressive weakness and atrophy of skeletal muscles…”
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RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy by Snider, Lauren, Asawachaicharn, Amy, Tyler, Ashlee E., Geng, Linda N., Petek, Lisa M., Maves, Lisa, Miller, Daniel G., Lemmers, Richard J.L.F., Winokur, Sara T., Tawil, Rabi, van der Maarel, Silvère M., Filippova, Galina N., Tapscott, Stephen J.

“…Deletion of a subset of the D4Z4 macrosatellite repeats in the subtelomeric region of chromosome 4q causes facioscapulohumeral muscular dystrophy (FSHD) when…”
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Characterization of microRNAs involved in embryonic stem cell states by Stadler, Bradford, Ivanovska, Irena, Mehta, Kshama, Song, Sunny, Nelson, Angelique, Tan, Yunbing, Mathieu, Julie, Darby, Christopher, Blau, C Anthony, Ware, Carol, Peters, Garrick, Miller, Daniel G, Shen, Lanlan, Cleary, Michele A, Ruohola-Baker, Hannele

“…Studies of embryonic stem cells (ESCs) reveal that these cell lines can be derived from differing stages of embryonic development. We analyzed common changes…”
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Facemasks: Perceptions and use in an ED population during COVID-19 by Eswaran, Vidya, Chang, Anna Marie, Wilkerson, R Gentry, O'Laughlin, Kelli N, Chinnock, Brian, Eucker, Stephanie A, Baumann, Brigitte M, Anaya, Nancy, Miller, Daniel G, Haggins, Adrianne N, Torres, Jesus R, Anderson, Erik S, Lim, Stephen C, Caldwell, Martina T, Raja, Ali S, Rodriguez, Robert M

“…Facemask use is associated with reduced transmission of SARS-CoV-2. Most surveys assessing perceptions and practices of mask use miss the most vulnerable…”
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Adeno-associated virus vectors integrate at chromosome breakage sites by Russell, David W, Miller, Daniel G, Petek, Lisa M

“…Adeno-associated virus (AAV) vectors transduce cells by multiple pathways, including integration at nonhomologous chromosomal locations by an unknown…”
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Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells by Choi, Minseung, Genereux, Diane P, Goodson, Jamie, Al-Azzawi, Haneen, Allain, Shannon Q, Simon, Noah, Palasek, Stan, Ware, Carol B, Cavanaugh, Chris, Miller, Daniel G, Johnson, Winslow C, Sinclair, Kevin D, Stöger, Reinhard, Laird, Charles D

“…In storing and transmitting epigenetic information, organisms must balance the need to maintain information about past conditions with the capacity to respond…”
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Foamy Virus Vector Integration Sites in Normal Human Cells by Trobridge, Grant D., Miller, Daniel G., Jacobs, Michael A., Allen, James M., Kiem, Hans-Peter, Kaul, Rajinder, Russell, David W.

“…Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have…”
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Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures by Haynes, Premi, Kernan, Kelly, Zhou, Suk-Lin, Miller, Daniel G

“…Facioscapulohumeral muscular dystrophy (FSHD) is most commonly inherited in an autosomal dominant pattern and caused by the abnormal expression of DUX4 in…”
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Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells by Beard, Brian C, Dickerson, David, Beebe, Kate, Gooch, Christina, Fletcher, James, Okbinoglu, Tulin, Miller, Daniel G, Jacobs, Michael A, Kaul, Rajinder, Kiem, Hans-Peter, Trobridge, Grant D

“…The potential for leukemia caused by retroviral vector integration has become a significant concern for hematopoietic stem cell gene therapy. We analyzed the…”
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Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells by MILLER, Daniel G, TROBRIDGE, Grant D, PETEK, Lisa M, JACOBS, Michael A, KAUL, Rajinder, RUSSELL, David W

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Endogenous DUX4 expression in FSHD myotubes is sufficient to cause cell death and disrupts RNA splicing and cell migration pathways by Rickard, Amanda M, Petek, Lisa M, Miller, Daniel G

“…Facioscapulohumeral muscular dystrophy (FSHD) is caused by chromatin relaxation that results in aberrant expression of the transcription factor Double Homeobox…”
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Reduced Computed Tomography Use in the Emergency Department Evaluation of Headache Was Not Followed by Increased Death or Missed Diagnosis by Miller, Daniel G, Vakkalanka, Priyanka, Moubarek, Mark L, Lee, Sangil, Mohr, Nicholas M

“…This study investigated whether a 9.6% decrease in the use of head computed tomography (HCT) for patients presenting to the emergency department (ED) with a…”
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Scurvy: Malnourishment in the Land of Plenty by Kluesner, Nicholas H., MD, Miller, Daniel G., MD

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Can Simulation Measure Differences in Task-Switching Ability Between Junior and Senior Emergency Medicine Residents? by Smith, Dustin, Miller, Daniel G, Cukor, Jeffrey

“…Work interruptions during patient care have been correlated with error. Task-switching is identified by the Accreditation Council for Graduate Medical…”
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Asymmetric bidirectional transcription from the FSHD-causing D4Z4 array modulates DUX4 production by Block, Gregory J, Petek, Lisa M, Narayanan, Divya, Amell, Amanda M, Moore, James M, Rabaia, Natalia A, Tyler, Ashlee, van der Maarel, Silvere M, Tawil, Rabi, Filippova, Galina N, Miller, Daniel G

“…Facioscapulohumeral Disease (FSHD) is a dominantly inherited progressive myopathy associated with aberrant production of the transcription factor, Double…”
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