Search Results - "Miller, DK"

Something About Frailty by Morley, John E, Perry, H Mitchell, Miller, Douglas K

“…Frailty is a commonly used term indicating older persons at increase risk for morbidity and mortality, and in some ways analogous in older persons with the…”
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Sigma-1 receptor antagonist PD144418 suppresses food reinforced operant responding in rats by Tapia, Melissa A., Lee, Jenna R., Gereau, Graydon B., Moore, Justin M., Weise, Valerie N., Mason, Kelsey L., Cessac, Mikala E., Bodeen, Jeffrey L., Miller, Dennis K., Will, Matthew J.

“…Sigma-1 (σ1) receptors have been investigated for their involvement in learning, rewarding and motivational processes, particularly as it relates to substances…”
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Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits by Wang, Qun, Sun, Albert Y., Simonyi, Agnes, Jensen, Michael D., Shelat, Phullara B., Rottinghaus, George E., MacDonald, Ruth S., Miller, Dennis K., Lubahn, Dennis E., Weisman, Gary A., Sun, Grace Y.

“…Increased oxidative stress has been regarded as an important underlying cause for neuronal damage induced by cerebral ischemia/reperfusion (I/R) injury. In…”
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Clinically Relevant Levels of Depressive Symptoms in Community-Dwelling Middle-Aged African Americans by Miller, Douglas K., Malmstrom, Theodore K., Joshi, Seema, Andresen, Elena M., Morley, John E., Wolinsky, Fredric D.

“…Objectives: To identify the prevalence of and potentially modifiable risk factors for clinically relevant levels of depressive symptoms in a population‐based…”
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Neighborhood Conditions and Risk of Incident Lower-Body Functional Limitations among Middle-aged African Americans by Schootman, Mario, Andresen, Elena M., Wolinsky, Fredric D., Malmstrom, Theodore K., Miller, J. Philip, Miller, Douglas K.

“…The authors investigated the association between observed neighborhood conditions and lower-body functional limitations (LBFLs) using data from 563 subjects of…”
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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death by Casciola-Rosen, L, Nicholson, D W, Chong, T, Rowan, K R, Thornberry, N A, Miller, D K, Rosen, A

“…Proteolysis mediated by the interleukin 1 beta-converting enzyme (ICE) homologues is an important mechanism of the apoptotic process. The ICE homologue…”
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Snowfall event characteristics from a high‑elevation site in the Southern Appalachian Mountains, USA by Martin, DT, Perry, LB, Miller, DK, Soulé, PT

“…Accurate assessment of snowfall patterns in high-elevation remote areas is essential to providing a foundation for further climatological analyses. The…”
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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis by Nicholson, Donald W, Ali, Ambereen, Thornberry, Nancy A, Vaillancourt, John P, Ding, Connie K, Gallant, Michel, Gareau, Yves, Griffin, Patrick R, Labelle, Marc, Lazebnik, Yuri A, Munday, Neil A, Raju, Sayyaparaju M, Smulson, Mark E, Yamin, Ting-Ting, Yu, Violeta L, Miller, Douglas K

“…The protease responsible for the cleavage of poly(ADP-ribose) polymerase and necessary for apoptosis has been purified and characterized. This enzyme, named…”
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Inner City, Middle-Aged African Americans Have Excess Frank and Subclinical Disability by Miller, Douglas K., Wolinsky, Fredric D., Malmstrom, Theodore K., Andresen, Elena M., Miller, J. Philip

“…Background.Healthy People 2010 seeks to decrease or eliminate the health disparities experienced by disadvantaged minority groups. Methods. African American…”
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The Interleukin-1 Receptor-associated Kinase Is Degraded by Proteasomes following Its Phosphorylation by Yamin, Ting-Ting, Miller, Douglas K.

“…Following interleukin (IL)-1 stimulation, the majority of the cellular interleukin-1 receptor-associated kinase (IRAK) translocates to a discrete subset of the…”
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CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis by Schlegel, J, Peters, I, Orrenius, S, Miller, D K, Thornberry, N A, Yamin, T T, Nicholson, D W

“…Cysteine proteases of the interleukin 1 beta Converting Enzyme (ICE)/CED-3 family have been implicated in the effector process of apoptosis in several systems,…”
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Further Evidence for the Importance of Subclinical Functional Limitation and Subclinical Disability Assessment in Gerontology and Geriatrics by Wolinsky, Fredric D., Miller, Douglas K., Andresen, Elena M., Malmstrom, Theodore K., Miller, J. Philip

“…Objectives. The objectives of this work were to determine the prevalence of self-reported subclinical status for functional limitation and disability at…”
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Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine by Miller, Dennis K, Sumithran, Sangeetha P, Dwoskin, Linda P

“…Bupropion, an efficacious antidepressant and smoking cessation agent, inhibits dopamine and norepinephrine transporters (DAT and NET, respectively). Recently,…”
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Characterization and Quantitation of NF- Kappa B Nuclear Translocation Induced by Interleukin-1 and Tumor Necrosis Factor- alpha : Development and Use of a High Capacity Fluorescence Cytometric System by Ding, GJF, Fischer, P A, Boltz, R C, Schmidt, JA, James, J C, Miller, D K

“…A new quantitative cytometric technique, termed the ArrayScan super(TM), is described and used to measure NF- Kappa B nuclear translocation induced by…”
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Cross-Sectional and Longitudinal Risk Factors for Falls, Fear of Falling, and Falls Efficacy in a Cohort of Middle-Aged African Americans by Andresen, Elena M., Wolinsky, Fredric D., Miller, J. Philip, Wilson, Margaret-Mary G., Malmstrom, Theodore K., Miller, Douglas K.

“…Purpose: The purpose of this study is to cross-sectionally and longitudinally identify risk factors for falls, fear of falling, and falls efficacy in…”
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Testosterone and leptin in older African-American men: Relationship to age, strength, function, and season by Perry, Horace M., Miller, Douglas K., Patrick, Ping, Morley, John E.

“…Testosterone (T) and bioavailable testosterone (BT) levels have been shown to decline with aging in Caucasian males. We are unaware of any studies that have…”
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Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters by Miller, Dennis K, Crooks, Peter A, Zheng, Guangrong, Grinevich, Vladimir P, Norrholm, Seth D, Dwoskin, Linda P

“…Lobeline attenuates the behavioral effects of psychostimulants in rodents and inhibits the function of nicotinic receptors (nAChRs), dopamine transporters…”
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Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death by Casciola-Rosen, L A, Miller, D K, Anhalt, G J, Rosen, A

“…The U1 small nuclear ribonucleoprotein particle is essential for splicing of precursor mRNA, an activity that depends upon both the RNA and protein components…”
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Lessons learned from the Northridge earthquake by Miller, Duane K.

“…The performance of welded connections in special moment resisting frames (SMRF) during the Northridge, California earthquake in January 1994 was influenced by…”
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The Future (History) of Socioeconomic Measurement and Implications for Improving Health Outcomes Among African Americans by Andresen, Elena M., Miller, Douglas K.

“…Socioeconomic status (SES) has powerful and complex impacts on health, and understanding the relationship between SES and health is essential for long-term…”
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