Search Results - "Miller, DH"

Differential diagnosis of suspected multiple sclerosis: a consensus approach by Miller, DH, Weinshenker, BG, Filippi, M, Banwell, BL, Cohen, JA, Freedman, MS, Galetta, SL, Hutchinson, M, Johnson, RT, Kappos, L, Kira, J, Lublin, FD, McFarland, HF, Montalban, X, Panitch, H, Richert, JR, Reingold, SC, Polman, CH

“…Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases that could better explain the clinical and paraclinical findings…”
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Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration by Kearney, H, Rocca, MA, Valsasina, P, Balk, L, Sastre-Garriga, J, Reinhardt, J, Ruggieri, S, Rovira, A, Stippich, C, Kappos, L, Sprenger, T, Tortorella, P, Rovaris, M, Gasperini, C, Montalban, X, Geurts, JJG, Polman, CH, Barkhof, F, Filippi, M, Altmann, DR, Ciccarelli, O, Miller, DH, Chard, DT

“…Background: Understanding long-term disability in multiple sclerosis (MS) is a key goal of research; it is relevant to how we monitor and treat the disease…”
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The significance of brain magnetic resonance imaging abnormalities at presentation with clinically isolated syndromes suggestive of multiple sclerosis. A 5-year follow-up study by Morrissey, S P, Miller, D H, Kendall, B E, Kingsley, D P, Kelly, M A, Francis, D A, MacManus, D G, McDonald, W I

“…A 5-year follow-up study was performed on 89 patients who had undergone brain magnetic resonance imaging (MRI) at presentation with an acute clinically…”
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Early MRI in optic neuritis: the risk for clinically definite multiple sclerosis by Swanton, JK, Fernando, KT, Dalton, CM, Miszkiel, KA, Altmann, DR, Plant, GT, Thompson, AJ, Miller, DH

“…MRI brain lesions at presentation with optic neuritis (ON) increase the risk for developing clinically definite (CD) multiple sclerosis (MS). More detailed…”
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ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis by Montalban, Xavier, Gold, Ralf, Thompson, Alan J, Otero-Romero, Susana, Amato, Maria Pia, Chandraratna, Dhia, Clanet, Michel, Comi, Giancarlo, Derfuss, Tobias, Fazekas, Franz, Hartung, Hans Peter, Havrdova, Eva, Hemmer, Bernhard, Kappos, Ludwig, Liblau, Roland, Lubetzki, Catherine, Marcus, Elena, Miller, David H, Olsson, Tomas, Pilling, Steve, Selmaj, Krysztof, Siva, Aksel, Sorensen, Per Soelberg, Sormani, Maria Pia, Thalheim, Christoph, Wiendl, Heinz, Zipp, Frauke

“…Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming available in the past years. There is a need for a reference tool compiling…”
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Brain lesion location and clinical status 20 years after a diagnosis of clinically isolated syndrome suggestive of multiple sclerosis by Dalton, CM, Bodini, B, Samson, RS, Battaglini, M, Fisniku, LK, Thompson, AJ, Ciccarelli, O, Miller, DH, Chard, DT

“…Background/Objectives: The objective of this study was to investigate associations between the spatial distribution of brain lesions and clinical outcomes in a…”
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Acute disseminated encephalomyelitis. MRI findings and the distinction from multiple sclerosis by Kesselring, J, Miller, D H, Robb, S A, Kendall, B E, Moseley, I F, Kingsley, D, du Boulay, E P, McDonald, W I

“…Brain MRI was performed on 12 patients with acute disseminated encephalomyelitis (ADEM). Multifocal white matter lesions indistinguishable from those seen in…”
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ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis by Montalban, X., Gold, R., Thompson, A. J., Otero‐Romero, S., Amato, M. P., Chandraratna, D., Clanet, M., Comi, G., Derfuss, T., Fazekas, F., Hartung, H. P., Havrdova, E., Hemmer, B., Kappos, L., Liblau, R., Lubetzki, C., Marcus, E., Miller, D. H., Olsson, T., Pilling, S., Selmaj, K., Siva, A., Sorensen, P. S., Sormani, M. P., Thalheim, C., Wiendl, H., Zipp, F.

“…Background and purpose Multiple sclerosis (MS) is a complex disease with new drugs becoming available in the past years. There is therefore a need for a…”
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Association of asymptomatic spinal cord lesions and atrophy with disability 5 years after a clinically isolated syndrome by Brownlee, WJ, Altmann, DR, Alves Da Mota, P, Swanton, JK, Miszkiel, KA, Wheeler-Kingshott, CAM Gandini, Ciccarelli, O, Miller, DH

“…Background: Spinal cord pathology is an important substrate for long-term disability in multiple sclerosis (MS). Objective: To investigate longitudinal changes…”
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Optic nerve magnetization transfer imaging and measures of axonal loss and demyelination in optic neuritis by Trip, SA, Schlottmann, PG, Jones, SJ, Li, W-Y., Garway-Heath, DF, Thompson, AJ, Plant, GT, Miller, DH

“…Magnetization transfer imaging is an MRI technique that provides quantitative information about in vivo tissue integrity, including myelin and axonal content,…”
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A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis by Polman, Chris H, O'Connor, Paul W, Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, Miller, David H, Phillips, J. Theodore, Lublin, Fred D, Giovannoni, Gavin, Wajgt, Andrzej, Toal, Martin, Lynn, Frances, Panzara, Michael A, Sandrock, Alfred W

“…This placebo-controlled, randomized trial of patients with relapsing multiple sclerosis demonstrated benefits of natalizumab (an α 4 integrin antagonist) in…”
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Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain by Schmierer, Klaus, Scaravilli, Francesco, Altmann, Daniel R., Barker, Gareth J., Miller, David H.

“…Several quantitative magnetic resonance (MR) measures are used to investigate multiple sclerosis (MS) in vivo. Precise quantitative investigation of the…”
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Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study by Kappos, Ludwig, Prof, Gold, Ralf, Prof, Miller, David H, Prof, MacManus, David G, MSc, Havrdova, Eva, MD, Limmroth, Volker, MD, Polman, Chris H, Prof, Schmierer, Klaus, PhD, Yousry, Tarek A, MD, Yang, Minhua, MS, Eraksoy, Mefkûre, Prof, Meluzinova, Eva, MD, Rektor, Ivan, MD, Dawson, Katherine T, MD, Sandrock, Alfred W, MD, O'Neill, Gilmore N, MB

“…Summary Background Oral fumarate (BG00012) might have dual anti-inflammatory and neuroprotective effects. Our aim was to assess the efficacy and safety of…”
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Editoriale by Miller, DH

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Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis by Trip, S. Anand, Schlottmann, Patricio G., Jones, Stephen J., Altmann, Daniel R., Garway-Heath, David F., Thompson, Alan J., Plant, Gordon T., Miller, David H.

“…Axonal loss is thought to be a likely cause of persistent disability after a multiple sclerosis relapse; therefore, noninvasive in vivo markers specific for…”
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Diffusion MRI in multiple sclerosis by ROVARIS, M, GASS, A, BAMMER, R, HICKMAN, S. J, CICCARELLI, O, MILLER, D. H, FILIPPI, M

“…Diffusion imaging is a quantitative, MR-based technique potentially useful for the study of multiple sclerosis (MS), due to its increased pathologic…”
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Feasibility of grey matter and white matter segmentation of the upper cervical cord in vivo: A pilot study with application to magnetisation transfer measurements by Yiannakas, M.C., Kearney, H., Samson, R.S., Chard, D.T., Ciccarelli, O., Miller, D.H., Wheeler-Kingshott, C.A.M.

“…Spinal cord pathology can be functionally very important in neurological disease. Pathological studies have demonstrated the involvement of spinal cord grey…”
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A Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis by Miller, David H, Khan, Omar A, Sheremata, William A, Blumhardt, Lance D, Rice, George P.A, Libonati, Michele A, Willmer-Hulme, Allison J, Dalton, Catherine M, Miszkiel, Katherine A, O'Connor, Paul W

“…Natalizumab is an antagonist of α 4 integrin, a very late adhesion antigen that is expressed on the surface of activated lymphocytes and monocytes. In this…”
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A Longitudinal Study of Abnormalities on MRI and Disability from Multiple Sclerosis by Brex, Peter A, Ciccarelli, Olga, O'Riordan, Jonathon I, Sailer, Michael, Thompson, Alan J, Miller, David H

“…Serial T 2 -weighted magnetic resonance imaging (MRI) studies were performed in 71 patients who first presented with optic neuritis or brain-stem or spinal…”
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Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes by Dalton, Catherine M., Chard, Declan T., Davies, Gerard R., Miszkiel, Katherine A., Altmann, Dan R., Fernando, Kryshani, Plant, Gordon T., Thompson, Alan J., Miller, David H.

“…While brain atrophy occurs early in the clinical course of multiple sclerosis, exactly how early, which tissues are affected and the rate at which early…”
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