Search Results - "Miller, Craig R."
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Statistical modeling to quantify the uncertainty of FoldX-predicted protein folding and binding stability
Published in BMC bioinformatics (12-11-2023)“…Computational methods of predicting protein stability changes upon missense mutations are invaluable tools in high-throughput studies involving a large number…”
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Risk of disease and willingness to vaccinate in the United States: A population-based survey
Published in PLoS medicine (15-10-2020)“…Vaccination complacency occurs when perceived risks of vaccine-preventable diseases are sufficiently low so that vaccination is no longer perceived as a…”
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Effects of trust, risk perception, and health behavior on COVID-19 disease burden: Evidence from a multi-state US survey
Published in PloS one (20-05-2022)“…Early public health strategies to prevent the spread of COVID-19 in the United States relied on non-pharmaceutical interventions (NPIs) as vaccines and…”
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Mutational Switch-Backs Can Accelerate Evolution of Francisella to a Combination of Ciprofloxacin and Doxycycline
Published in Frontiers in microbiology (09-05-2022)“…Combination antimicrobial therapy has been considered a promising strategy to combat the evolution of antimicrobial resistance. is the causative agent of…”
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Priming With Rhinovirus Protects Mice Against a Lethal Pulmonary Coronavirus Infection
Published in Frontiers in immunology (30-05-2022)“…Rhinoviruses (RV) have been shown to inhibit subsequent infection by heterologous respiratory viruses, including influenza viruses and severe acute respiratory…”
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A new method for estimating the size of small populations from genetic mark-recapture data
Published in Molecular ecology (01-06-2005)“…The use of non‐invasive genetic sampling to estimate population size in elusive or rare species is increasing. The data generated from this sampling differ…”
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Capwire: a R package for estimating population census size from non‐invasive genetic sampling
Published in Molecular ecology resources (01-01-2013)“…Non‐invasive genetic sampling is an increasingly popular approach for investigating the demographics of natural populations. This has also become a useful tool…”
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A long-term population monitoring approach for a wide-ranging carnivore: Noninvasive genetic sampling of gray wolf rendezvous sites in Idaho, USA
Published in The Journal of wildlife management (01-08-2014)“…Various monitoring methods have been developed for large carnivores, but not all are practical or sufficiently accurate for long-term monitoring over large…”
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Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses
Published in PloS one (02-06-2017)“…The severity of respiratory viral infections is partially determined by the cellular response mounted by infected lung epithelial cells. Disease prevention and…”
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10
Global Composition of the Bacteriophage Community in Honey Bees
Published in mSystems (26-04-2022)“…The microbial communities in animal digestive systems are critical for host development and health. They stimulate the immune system during development,…”
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Assessing Allelic Dropout and Genotype Reliability Using Maximum Likelihood
Published in Genetics (Austin) (01-01-2002)“…A growing number of population genetic studies utilize nuclear DNA microsatellite data from museum specimens and noninvasive sources. Genotyping errors are…”
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Changing folding and binding stability in a viral coat protein: a comparison between substitutions accessible through mutation and those fixed by natural selection
Published in PloS one (18-11-2014)“…Previous studies have shown that most random amino acid substitutions destabilize protein folding (i.e. increase the folding free energy). No analogous studies…”
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New Perspectives on Ebola Virus Evolution
Published in PloS one (01-08-2016)“…Since the recent devastating outbreak of Ebola virus disease in western Africa, there has been significant effort to understand the evolution of the deadly…”
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14
The consistency of beneficial fitness effects of mutations across diverse genetic backgrounds
Published in PloS one (24-08-2012)“…Parallel and convergent evolution have been remarkably common observations in molecular adaptation but primarily in the context of the same genotype adapting…”
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history of effective population size and genetic diversity in the Yellowstone grizzly (Ursus arctos): implications for conservation
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2003)“…Protein, mtDNA, and nuclear microsatellite DNA analyses have demonstrated that the Yellowstone grizzly bear has low levels of genetic variability compared with…”
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The treacheries of adaptation
Published in Science (American Association for the Advancement of Science) (25-10-2019)“…As fitness rises during adaptive evolution, the cost of mutation may escalate as well One of Darwin's great insights was that he took the widespread…”
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Rhinovirus Reduces the Severity of Subsequent Respiratory Viral Infections by Interferon-Dependent and -Independent Mechanisms
Published in mSphere (30-06-2021)“…Coinfection by heterologous viruses in the respiratory tract is common and can alter disease severity compared to infection by individual virus strains. We…”
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First-step mutations for adaptation at elevated temperature increase capsid stability in a virus
Published in PloS one (29-09-2011)“…The relationship between mutation, protein stability and protein function plays a central role in molecular evolution. Mutations tend to be destabilizing,…”
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Initiating a watch list for Ebola virus antibody escape mutations
Published in PeerJ (San Francisco, CA) (16-02-2016)“…The 2014 Ebola virus (EBOV) outbreak in West Africa is the largest in recorded history and resulted in over 11,000 deaths. It is essential that strategies for…”
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Genetically Determined Variation in Lysis Time Variance in the Bacteriophage φX174
Published in G3 : genes - genomes - genetics (01-04-2016)“…Researchers in evolutionary genetics recently have recognized an exciting opportunity in decomposing beneficial mutations into their proximal, mechanistic…”
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