Search Results - "Miller, Carl W."
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Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray
Published in Blood (15-01-2008)“…Pediatric acute lymphoblastic leukemia (ALL) is a malignant disease resulting from accumulation of genetic alterations. A robust technology, single nucleotide…”
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Epigenetic Silencing of the Candidate Tumor Suppressor Gene Per1 in Non–Small Cell Lung Cancer
Published in Clinical cancer research (01-03-2007)“…Purpose: Epigenetic events are a critical factor contributing to cancer development. The purpose of this study was to identify tumor suppressor genes silenced…”
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FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer
Published in International journal of cancer (01-03-2007)“…The transcription factor Forkhead‐box A1 (Foxa1), a member of the FOX class of transcription factors, has been implicated in the pathogenesis of lung,…”
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ERCC5 Is a Novel Biomarker of Ovarian Cancer Prognosis
Published in Journal of clinical oncology (20-06-2008)“…To identify a biomarker of ovarian cancer response to chemotherapy. PATIENTS AND METHODS Study: participants had epithelial ovarian cancer treated with surgery…”
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Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2008)“…High-resolution single nucleotide polymorphism genomic microarray (SNP-chip) is a useful tool to define gene dosage levels over the whole genome, allowing…”
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Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype
Published in Haematologica (Roma) (01-02-2009)“…Acute myeloid leukemia is a clonal hematopoietic malignant disease; about 45-50% of cases do not have detectable chromosomal abnormalities. Here, we identified…”
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Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk
Published in Gynecologic oncology (01-03-2007)“…Abstract Objectives. MDM2 is an important negative regulator of the p53 tumor suppressor protein. A naturally occurring T/G single nucleotide polymorphism…”
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Genome-Wide Loss of Heterozygosity and Uniparental Disomy in BRCA1/2-Associated Ovarian Carcinomas
Published in Clinical cancer research (01-12-2008)“…Purpose: The importance of the BRCA gene products in maintaining genomic stability led us to hypothesize that BRCA-associated and sporadic ovarian cancers…”
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Sociodemographic and health-related determinants of breast and cervical cancer screening behavior, 2005
Published in Journal of obstetric, gynecologic, and neonatal nursing (01-01-2008)“…To identify sociodemographic and health-related determinants of Breast and Cervical Cancer Screening behaviors and evaluate progress toward Healthy People 2010…”
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Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors
Published in Genes chromosomes & cancer (01-01-2002)“…Checkpoint genes, activated in response to DNA damage and other stresses, are frequently targeted for alteration in cancer. Checkpoint kinase 2 (CHK2, CDS1,…”
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Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells
Published in Leukemia research (01-07-2009)“…Abstract Asparagine synthetase (ASNS) is an enzyme expressed ubiquitously in mammalian cells. Here, we discovered two 14-bp tandem repeat (2R, wild-type)…”
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Cyr61 Suppresses Growth of Human Endometrial Cancer Cells
Published in The Journal of biological chemistry (17-12-2004)“…Cyr61 (CCN1) is a member of the CCN protein family; these secreted proteins are involved in diverse biological processes such as cell adhesion, angiogenesis,…”
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Xeroderma pigmentosum complementation group C single‐nucleotide polymorphisms in the nucleotide excision repair pathway correlate with prolonged progression‐free survival in advanced ovarian cancer
Published in Cancer (01-02-2012)“…BACKGROUND: The nucleotide excision repair (NER) pathway is the principal DNA repair pathway for removing bulky platinum DNA adducts. Suboptimal DNA repair may…”
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Health status, physical disability, and obesity among adult Mississippians with chronic joint symptoms or doctor-diagnosed arthritis: findings from the Behavioral Risk Factor Surveillance System, 2003
Published in Preventing chronic disease (01-07-2008)“…The purpose of this study was to analyze 2003 Mississippi Behavioral Risk Factor Surveillance System (BRFSS) data to describe the health of Mississippians with…”
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Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias
Published in Leukemia research (01-04-2001)“…Checkpoint genes code for a family of proteins which sense DNA damage in eukaryotic cells. They play an important role in the control of the cell cycle. The…”
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Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations
Published in Blood (19-02-2009)“…Acute promyelocytic leukemia (APL) is a hematopoietic malignant disease characterized by the chromosomal translocation t(15;17), resulting in the formation of…”
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Chromosomal abnormalities and novel disease‐related regions in progression from Barrett's esophagus to esophageal adenocarcinoma
Published in International journal of cancer (15-11-2009)“…Barrett's esophagus (BE) is a metaplastic condition caused by chronic gastroesophageal reflux which represents an early step in the development of esophageal…”
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Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein α in myelodysplastic syndromes and acute myeloid leukemias
Published in Blood (15-02-2002)“…The CCAAT/enhancer binding protein α (C/EBPα) protein is essential for proper lung and liver function and granulocytic and adipose tissue differentation. It…”
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Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors
Published in International journal of hematology (01-04-2003)“…A mutation of the p16(INK4a)-binding domain of the cyclin dependent kinase 4 (CDK4) gene, R24C, has been reported in some cases of melanoma. This mutation…”
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Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray
Published in Experimental hematology (01-11-2008)“…Objective Myeloproliferative disorders (MPD) are clonal hematopoietic diseases that include polycythemia vera (PV), essential thrombocytosis (ET), and primary…”
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