Search Results - "Miller, Antonia G."

Identification of a Retinal Aldosterone System and the Protective Effects of Mineralocorticoid Receptor Antagonism on Retinal Vascular Pathology by Wilkinson-Berka, Jennifer L, Tan, Genevieve, Jaworski, Kassie, Miller, Antonia G

“…Blockade of the renin–angiotensin–aldosterone system (RAAS) is being evaluated as a treatment for diabetic retinopathy; however, whether the mineralocorticoid…”
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Prorenin stimulates a pro-angiogenic and pro-inflammatory response in retinal endothelial cells and an M1 phenotype in retinal microglia by Zhu, Tong, Miller, Antonia G, Deliyanti, Devy, Berka, David R, Agrotis, Alex, Campbell, Duncan J, Wilkinson-Berka, Jennifer L

“…Summary Angiogenesis and inflammation are causative factors in the development of neovascular retinopathies. These processes involve the retinal endothelium…”
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RILLKKMPSV Influences the Vasculature, Neurons and Glia, and (Pro)Renin Receptor Expression in the Retina by Wilkinson-Berka, Jennifer L, Heine, Ronen, Tan, Genevieve, Cooper, Mark E, Hatzopoulos, Kate M, Fletcher, Erica L, Binger, Katrina J, Campbell, Duncan J, Miller, Antonia G

“…The (pro)renin receptor [(P)RR] is implicated in organ pathology. We examined the cellular location of the (P)RR and whether a putative (P)RR antagonist,…”
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Glyoxalase I Is Critical for Human Retinal Capillary Pericyte Survival under Hyperglycemic Conditions by Miller, Antonia G., Smith, Dawn G., Bhat, Manjunatha, Nagaraj, Ram H.

“…Retinal capillary pericytes undergo premature death, possibly by apoptosis, during the early stages of diabetic retinopathy. The α-oxoaldehyde, methylglyoxal…”
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Prorenin and the (pro)renin receptor: recent advances and implications for retinal development and disease by Wilkinson-Berka, Jennifer L, Miller, Antonia G, Binger, Katrina J

“…PURPOSE OF REVIEWThe renin–angiotensin system (RAS) is a treatment target for diabetic retinopathy and possibly other ocular diseases. However, angiotensin II…”
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Update on the treatment of diabetic retinopathy by Wilkinson-Berka, Jennifer L, Miller, Antonia G

“…Retinopathy is the most feared complication of diabetes, compromising quality of life in most sufferers. Almost all patients with type 1 diabetes will develop…”
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NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy by Wilkinson-Berka, Jennifer L, Deliyanti, Devy, Rana, Indrajeetsinh, Miller, Antonia G, Agrotis, Alex, Armani, Roksana, Szyndralewiez, Cédric, Wingler, Kirstin, Touyz, Rhian M, Cooper, Mark E, Jandeleit-Dahm, Karin A, Schmidt, Harald H H W

“…Ischemic retinal diseases such as retinopathy of prematurity are major causes of blindness due to damage to the retinal microvasculature. Despite this clinical…”
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Neovascularization Is Attenuated With Aldosterone Synthase Inhibition in Rats With Retinopathy by Deliyanti, Devy, Miller, Antonia G, Tan, Genevieve, Binger, Katrina J, Samson, Andre L, Wilkinson-Berka, Jennifer L

“…Neovascularization is a hallmark feature of retinopathy of prematurity and diabetic retinopathy. Type 1 angiotensin receptor blockade reduces…”
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Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function by Miller, Antonia G, Tan, Genevieve, Binger, Katrina J, Pickering, Raelene J, Thomas, Merlin C, Nagaraj, Ram H, Cooper, Mark E, Wilkinson-Berka, Jennifer L

“…Advanced glycation end products (AGEs) and the renin-angiotensin system (RAS) are both implicated in the development of diabetic retinopathy. How these…”
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Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability by Mutreja, Isha, Warring, Suzanne L, Lim, Khoon S, Swadi, Tara, Clinch, Keith, Mason, Jennifer M, Sheen, Campbell R, Thompson, Dion R, Ducati, Rodrigo G, Chambers, Stephen T, Evans, Gary B, Gerth, Monica L, Miller, Antonia G, Woodfield, Tim B. F

“…The rise of antibiotic resistance, coupled with increased expectations for mobility in later life, is creating a need for biofilm inhibitors and delivery…”
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The role of dicarbonyl compounds in non-enzymatic crosslinking: a structure–activity study by Meade, Susie J, Miller, Antonia G, Gerrard, Juliet A

“…The Maillard reaction is a complex network of reactions that has been shown to result in the non-enzymatic crosslinking of proteins. Recent attention has…”
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Prorenin and the (pro)renin receptor: do they have a pathogenic role in the retina? by Wilkinson-Berka, Jennifer L, Miller, Antonia G, Fletcher, Erica L

“…Prorenin, the inactive precursor of renin has been suggested to be an indicator of diabetic complications including retinopathy. This concept was originally…”
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Assessment of Protein Function following Cross-Linking by α-Dicarbonyls by MILLER, ANTONIA G., GERRARD, JULIET A.

“…: Protein cross‐linking via the Maillard reaction with α‐dicarbonyl compounds has been the subject of intense scrutiny in the literature. We report here a…”
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New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics by Miller, Antonia G, Meade, Susie J, Gerrard, Juliet A

“…Protein crosslinking via the Maillard reaction with α-dicarbonyl compounds has been the subject of intense literature scrutiny. We report here a systematic…”
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The renin-angiotensin system and advanced glycation end-products in diabetic retinopathy: impacts and synergies by Miller, Antonia G, Zhu, Tong, Wilkinson-Berka, Jennifer L

“…Diabetic retinopathy is a major cause of vision impairment and blindness and represents a significant health burden throughout the world. There is considerable…”
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A continuous enzyme assay and characterisation of fructosyl amine oxidase enzymes (EC 1.5.3) by Miller, Antonia G., Hegge, Stephan, Uhlmann, Andrea, Gerrard, Juliet A.

“…Enzymatic reversal of the Maillard reaction is a growing area of research. Fructosyl amine oxidase enzymes (EC 1.5.3) have attracted recent attention through…”
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What residues are required for protein crosslinking and how does this process affect enzyme function? by Miller, Antonia G, Gerrard, Juliet A

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1030 ACTIVATION OF RETINAL MICROGLIA IS ATTENUATED WITH ANGIOTENSIN II AND ALDOSTERONE BLOCKADE by Rana, Indrajeetsinh, Miller, Antonia G., Beh, Sze Y., Agrotis, Alex, Wilkinson-Berka, Jennifer L.

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Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-1 Function by MILLER, Antonia G, TAN, Genevieve, BINGER, Katrina J, PICKERING, Raelene J, THOMAS, Merlin C, NAGARAJ, Ram H, COOPER, Mark E, WILKINSON-BERKA, Jennifer L

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Glyoxalase I Plays a Critical Role in the Prevention of High Glucose-Induced Apoptosis in Human Retinal Pericytes by Miller, Antonia G, Smith, Dawn G, Nagaraj, Ram H

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