Search Results - "Miller, Amy L."

The Mouse Grimace Scale: A Clinically Useful Tool? by Miller, Amy L, Leach, Matthew C

“…Medical research has a heavy and continuing demand for rodent models across a range of disciplines. Behavioural assessment of pain in such models is highly…”
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The assessment of post-vasectomy pain in mice using behaviour and the Mouse Grimace Scale by Leach, Matthew C, Klaus, Kristel, Miller, Amy L, Scotto di Perrotolo, Maud, Sotocinal, Susana G, Flecknell, Paul A

“…Current behaviour-based pain assessments for laboratory rodents have significant limitations. Assessment of facial expression changes, as a novel means of pain…”
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A Stormy Heart by Kratka, Allison, Tedrow, Usha B., Mitchell, Richard N., Miller, Amy L., Loscalzo, Joseph

“…A 68-year-old woman with a history of hypertension and obstructive sleep apnea presented to the emergency department with palpitations, lightheadedness, and…”
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Welfare Assessment, End-Point Refinement and the Effects of Non-Aversive Handling in C57BL/6 Mice with Lewis Lung Cancer by Miller, Amy L, Roughan, Johnny V

“…Cancer-bearing mice are at risk of developing anxiety, pain, or malaise. These conditions may not only harm welfare but could also undermine data quality and…”
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The Influence of Isoflurane Anaesthesia on the Rat Grimace Scale by Miller, Amy L, Golledge, Huw D R, Leach, Matthew C

“…Over 234,000 rats were used in regulated procedures in the UK in 2014, many of which may have resulted in some degree of pain. When using animals in research,…”
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The effect of handling method on the mouse grimace scale in two strains of laboratory mice by Miller, Amy L, Leach, Matthew C

“…Pain assessment in laboratory animals is an ethical and legal requirement. The mouse grimace scale (MGS) is a new method of pain assessment deemed to be both…”
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The Impact of Age on the Epidemiology of Atrial Fibrillation Hospitalizations by Naderi, Sahar, MD, MHS, Wang, Yun, PhD, Miller, Amy L., MD, PhD, Rodriguez, Fátima, MD, MPH, Chung, Mina K., MD, Radford, Martha J., MD, Foody, JoAnne M., MD

“…Abstract Background Given that 4 million individuals in the United States have atrial fibrillation, understanding the epidemiology of this disease is crucial…”
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Association of Hospital Myocardial Infarction Volume with Adherence to American College of Cardiology/American Heart Association Performance Measures: Insights from the National Cardiovascular Data Registry by Harrison, Robert W., MD, Simon, DaJuanicia, MS, Miller, Amy L., MD, PhD, de Lemos, James A., MD, Peterson, Eric D., MD, MPH, Wang, Tracy Y., MD, MHS, MSc

“…Abstract Background Adherence to guideline-based therapy improves patient outcomes after acute myocardial infarction (AMI) and hospital AMI volume is…”
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Evaluating Pain and Analgesia Effectiveness Following Routine Castration in Rabbits Using Behavior and Facial Expressions by Miller, Amy L, Clarkson, Jasmine M, Quigley, Caroline, Neville, Vikki, Krall, Caroline, Geijer-Simpson, Annika, Flecknell, Paul A, Leach, Matthew C

“…Prevention of pain in rabbits is a priority for both welfare and validity of scientific data. We aimed to determine if the rabbit grimace scale (RbtGS) could…”
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Automated tracking to measure behavioural changes in pigs for health and welfare monitoring by Matthews, Stephen G., Miller, Amy L., PlÖtz, Thomas, Kyriazakis, Ilias

“…Since animals express their internal state through behaviour, changes in said behaviour may be used to detect early signs of problems, such as in animal…”
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Early detection of health and welfare compromises through automated detection of behavioural changes in pigs by Matthews, Stephen G., Miller, Amy L., Clapp, James, Plötz, Thomas, Kyriazakis, Ilias

“…•Recent developments in automatically detecting compromised pig health and welfare.•Five categories of behaviour are reviewed.•Behaviours mapped to sensors…”
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Hard to Swallow. Reply by Litt, Michael J, Montgomery, Mary W, Miller, Amy L

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Determining the preferred liquid reward in adult C57BL/6 mice by Miller, Amy L, Leach, Matthew C

“…Using food rewards to motivate mice is commonplace in behavioural research. Using a reward which is highly desirable is of benefit, as it can reduce the need…”
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Conceptual and methodological issues relating to pain assessment in mammals: The development and utilisation of pain facial expression scales by McLennan, Krista M., Miller, Amy L., Dalla Costa, Emanuela, Stucke, Diana, Corke, Murray J., Broom, Donald M., Leach, Matthew C.

“…•There are conceptual and methodological problems for animal pain assessment.•Facial expression scales are valid, reliable pain recognition and evaluation…”
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Ventricular Tachycardia in Cardiac Sarcoidosis: Characterization of Ventricular Substrate and Outcomes of Catheter Ablation by Kumar, Saurabh, Barbhaiya, Chirag, Nagashima, Koichi, Choi, Eue-Keun, Epstein, Laurence M, John, Roy M, Maytin, Melanie, Albert, Christine M, Miller, Amy L, Koplan, Bruce A, Michaud, Gregory F, Tedrow, Usha B, Stevenson, William G

“…BACKGROUND—Cardiac sarcoid–related ventricular tachycardia (VT) is a rare disorder; the underlying substrate and response to ablation are poorly understood. We…”
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Hard to Swallow by Litt, Michael J, Montgomery, Mary W, Small, Kirstin M, Miller, Amy L, Loscalzo, Joseph

“…A previously healthy 20-year-old college student presented before the Covid-19 pandemic with a 3-day history of throat pain, malaise, cough, and chills. She…”
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Missing the Target by Iriarte, Christopher, Vaitkevicius, Henrikas, Marty, Francisco M, Miller, Amy L, Loscalzo, Joseph

“…A 58-year-old man presented to the emergency department with a 2-week history of pelvic pain on the left side, with subsequent development of severe pain in…”
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Hypertensive Heartbreak by Lau, Emily S, Scirica, Benjamin, Schaefer, Inga-Marie, Miller, Amy L, Loscalzo, Joseph

“…A 61-year-old man with chronic knee pain was evaluated for elective total knee arthroplasty. During the preoperative visit, his blood pressure was 178/92 mm…”
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Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models by Lofgren, Jennifer, Miller, Amy L, Lee, Claudia Chui Shan, Bradshaw, Carla, Flecknell, Paul, Roughan, Johnny

“…Murine orthotopic cancer models often require surgery, potentially causing pain or distress. However, analgesics are often withheld because they may alter…”
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A Rapid Change in Pressure by D’Silva, Kristin, Cockrill, Barbara, Anderson, William J, Miller, Amy L, Loscalzo, Joseph

“…A 74-year-old woman presented with a 6-week history of progressive dyspnea on exertion. She also noted a nonproductive cough, fatigue, loss of appetite, and an…”
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