Search Results - "Millenbaugh, Nancy"
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Targeted laser therapy synergistically enhances efficacy of antibiotics against multi-drug resistant Staphylococcus aureus and Pseudomonas aeruginosa biofilms
Published in Nanomedicine (01-08-2019)“…The growing prevalence of biofilm-associated multi-drug resistant (MDR) bacteria necessitates the innovation of non-traditional approaches to improve the…”
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Antifungal peptide-loaded alginate microfiber wound dressing evaluated against Candida albicans in vitro and ex vivo
Published in European journal of pharmaceutics and biopharmaceutics (01-12-2024)“…[Display omitted] Invasive fungal infections have high mortality rates, and many current antimycotics are limited by host toxicity and drug resistance. Recent…”
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DNA aptamers as a novel approach to neutralize Staphylococcus aureus α-toxin
Published in Biochemical and biophysical research communications (14-02-2014)“…•DNA aptamers were isolated against Staphylococcus aureus α-toxin using SELEX methodology.•Four of the aptamers inhibited α-toxin-induced cell death in Jurkat…”
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Photothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles
Published in International journal of nanomedicine (01-01-2015)“…The continued emergence of multidrug resistant bacterial infections and the decline in discovery of new antibiotics are major challenges for health care…”
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Optimized peptide extraction method for analysis of antimicrobial peptide Kn2-7/dKn2-7 stability in human serum by LC–MS
Published in Future science OA (01-07-2022)“…To develop an extraction protocol and determine stability for antimicrobial peptide (AMP) Kn2-7 and its -enantiomer dKn2-7 in human serum. We compared use of…”
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Enzymatic degradation of in vitro Staphylococcus aureus biofilms supplemented with human plasma
Published in Infection and drug resistance (01-01-2016)“…Enzymatic debridement is a therapeutic strategy used clinically to remove necrotic tissue from wounds. Some of the enzymes utilized for debridement have been…”
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Antifungal Activity of Synthetic Scorpion Venom-Derived Peptide Analogues Against Candida albicans
Published in International journal of peptide research and therapeutics (01-03-2021)“…Fungal infections are becoming a serious problem due to their high morbidity and mortality combined with the rise in drug resistance and dearth of new…”
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Gene Expression Changes in the Skin of Rats Induced by Prolonged 35 GHz Millimeter-Wave Exposure
Published in Radiation research (01-03-2008)“…Millenbaugh, N. J., Roth, C., Sypniewska, R., Chan, V., Eggers, J. S., Kiel, J. L., Blystone, R. V. and Mason, P. A. Gene Expression Changes in the Skin of…”
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Protein changes in macrophages induced by plasma from rats exposed to 35 GHz millimeter waves
Published in Bioelectromagnetics (01-12-2010)“…A macrophage assay and proteomic screening were used to investigate the biological activity of soluble factors in the plasma of millimeter wave‐exposed rats…”
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Comparison of blood pressure and thermal responses in rats exposed to millimeter wave energy or environmental heat
Published in Shock (Augusta, Ga.) (01-06-2006)“…Electromagnetic fields at millimeter wave lengths are being developed for commercial and military use at power levels that can cause temperature increases in…”
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Pharmacodynamics of immediate and delayed effects of paclitaxel : Role of slow apoptosis and intracellular drug retention
Published in Cancer research (Chicago, Ill.) (15-05-1998)“…The kinetics of the time-dependent antitumor effects of paclitaxel are not fully understood; some literature reports indicate a higher activity by prolonging…”
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Cytostatic and apoptotic effects of paclitaxel in human ovarian tumors
Published in Pharmaceutical research (1998)“…The present study evaluated the cytostatic and apoptotic effects of a 24-hr paclitaxel treatment in ovarian tumors. Three-dimensional histocultures of surgical…”
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Design and analysis of in vitro antitumor pharmacodynamic studies
Published in Cancer research (Chicago, Ill.) (15-11-1995)“…The relationship between drug concentration (C), exposure time (t), and the resulting effect (h) for a chemotherapeutic agent is expressed as Cn x t = h. The…”
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14
Accuracy and precision of pharmacodynamic exponent
Published in Pharmaceutical research (1999)Get full text
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TNF Receptor 1, IL-1 Receptor, and iNOS Genetic Knockout Mice Are Not Protected from Anthrax Infection
Published in Biochemical and biophysical research communications (22-03-2002)“…Anthrax produces at least two toxins that cause an intense systemic inflammatory response, edema, shock, and eventually death. The relative contributions of…”
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A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect
Published in Cancer chemotherapy and pharmacology (2000)“…The pharmacodynamics of most drugs follow the empirical relationship, C(n) x T = h, where C is drug concentration, T is exposure time and h is drug exposure…”
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Cancer pharmacodynamic study design and data analysis: Theory and practice
Published 01-01-1998“…In the pharmacodynamic relationship between the drug concentration (C) and exposure time (T) and the drug exposure constant (h), $\rm C\sp{n}\times T=h,$ the…”
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Dissertation -
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Percutaneous absorption of 2',3'-dideoxyinosine in rats
Published in Pharmaceutical research (01-06-1994)“…This study explored the topical route for administering of 2',3'-dideoxyinosine (ddI), a nucleoside analog used for treating patients with acquired…”
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